The National Cancer Imaging Archive (NCIA) In Action: An Introduction for Users A Tool Demonstration from caBIG™ Carl Jaffe, MD NCI-Cancer Imaging Program.

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Presentation transcript:

The National Cancer Imaging Archive (NCIA) In Action: An Introduction for Users A Tool Demonstration from caBIG™ Carl Jaffe, MD NCI-Cancer Imaging Program Eliot Siegel, MD University of Maryland School of Medicine VA Maryland Healthcare System March, 2008

Agenda and Goal 1.Overview and Introduction to NCIA 2.NCIA Functionality 3.Resources and Next Steps The goal of this demo is to introduce you to the capabilities and benefits of NCIA, a caBIG™ tool that can easily be adopted, adapted to, or interfaced with.

caBIG™ Overview caBIG™ is an information network that allows researchers, clinicians, and patients to share data and knowledge to accelerate the discovery of new diagnostics and therapeutics in order to improve patient outcomes. caBIG™ Vision Connect the cancer research community through a shareable, interoperable infrastructure Deploy and extend standard rules and a common language to more easily share information Build or adapt tools for collecting, analyzing, integrating and disseminating information associated with cancer research and care

Introduction to the National Cancer Imaging Archive (NCIA)

NCIA in the Research Continuum The NCIA is a software suite that provides a means of capturing, storing and sharing medical images. Clinical Research Pathology Molecular Biology Imaging

How NCIA Promotes Advances in Imaging Related Research Challenges NCIA Provided Solutions NCIA is optimized for diagnostic medical images, and has special software for acquisition, storage, and retrieval Conventional databases do not address imaging specific requirements and standards Images and related data can be located and retrieved digitally Imaging data is physically transported NCIA allows for a “federation” of cooperating storage sites, which can be searched using a single query Medical images are located in multiple repositories accessed separately via different interfaces A free and open source imaging informatics infrastructure that provides cost effective support for shared or customizable databases Individualized solutions for secure storage and retrieval of medical images are costly, time consuming, and ineffective

Using the NCIA: Who and Why? Target Users All researchers who use images as part of their research The medical imaging community The medical software development industry Core Functions Secure and de-identified acquisition of medical images from clinical imaging modalities or Picture Archiving and Communication Systems (PACS) Ability to search studies utilizing specified imaging modalities and parameters Role based retrieval of specified imaging studies, imaging series, or individual images Ability to save a recurring query, as well as measurements made on selected images Ability to safely resume an interrupted download

How does the NCIA fit within a typical user’s workflow? Trial findings are shared between sites via disparate means (i.e. spreadsheet, table, etc.) Current Workflow NCIA Supported Workflow Coordinating Centers (CC) approve Participating Centers (PC) for trial work Physical transportation of trial data from CC to PC PCs query, view, and measure trial images with their own systems Image measurements made by the PCs are saved in the NCIA, and are readily available to all sites PCs access data via a web interface, and perform image analysis uniformly CC grants PC permission to view image data in the NCIA Coordinating Centers (CC) approve Participating Centers (PC) for trial work Use Case: Multi-institution trial of lung cancer response to drug therapy

Demonstration of the National Cancer Imaging Archive (NCIA)

NCIA Demo: Home Page

NCIA Demo: Using the Search Criteria

NCIA Demo: Search Results / Selecting Images for Download

NCIA Demo: Image Visualization

NCIA Demo: Accessing a Local DICOM Viewer (i.e. OSIRIX)

A Quick Review: Key Functions and Benefits of the NCIA Scheduled Adopters: VA Maryland Healthcare System Single Point of Access to Images for: Development and validation of analytical software for lesion detection and classification Accelerated diagnostic imaging decision making Quantitative imaging assessment of drug response Clinical trial collaboration and coordination Academic research with medical images Teaching 2. Web-based Visualization: Visualization of DICOM images and related data based on NCIA query results Ability to download images to any medical image viewer using a “shopping cart” method

Tool Features Under Development Free and open source tools for more sophisticated central or distributed visualization of DICOM images Ability to have multiple readers annotate and mark-up medical images using “Annotations & Imaging Markup” (AIM) format Ability to search databases for image features based on human or machine analysis

A Glance at the Underlying Technology Tool Platform: Web / remote application with data uploads and downloads through a web interface Key Prerequisites (for a local installation): System requirements: Minimal requirements include a Windows or Linux operating system with sufficient hard drive capacity and 3GB of RAM. IT Support: Database administrators with experience in installing and supporting web based applications. End-User Readiness: Staff experienced in extracting images from imaging modalities or PACS, with the connectivity and ability to submit them to the field center.

Resources and Next Steps

Two Pathways: Adopt or Adapt Interested organizations are not required to adopt this caBIG™ application to connect with caBIG™ There are other ways to share data and use common data elements and controlled vocabularies by adapting current or non-caBIG™ applications

The Next Step: Accessing Online Resources for NCIA RESOURCEADDRESSDESCRIPTION NCIA Online Home page of the NCIA portal Tool Landing Page Tool summary available on the caBIG TM Website NCI Center for Bioinformatics Applications Support (and Access to Demo Passwords and Logins) address for the NCI CBIIT Help Desk Software Development Project Site Online software development repository for NCI CBIIT NCIA Listserv Signup Signup page on list.nih.gov for NCIA Announcements caBIG Imaging Community Listserv Signup Signup page on list.nih.gov for the caBIG TM Imaging Community

NCIA: Next Steps Release Information Available Now: Submission of images to the NCI Contact: Available Now: NCI CBIIT support for local installation of NCIA Contact: Anand Basu, Applications Director, NCI CBIIT Development Schedule The NCIA will have periodic releases to provide regular feature enhancements NCI CBIIT plans to provide ongoing production level support Support Available Technical support is available via NCI CBIIT Contact: Telephone (301) / Toll Free:

Thank You for Attending! Feedback? -Did you get useful information from this presentation? -What additional information or future presentation topics would you like to see? Send your feedback to Anand Basu, NCI CBIIT Applications Director, at