Necator americanus and Ancylostoma duodenale

 It has been estimated that greater than 2 billion people are infected with soil- transmitted helminths  880 million are children  Up to 740 million are infected with Hookworms  Warm, moist regions  Regions of poor sanitation  Regions lacking proper water filtration  Thrive in impoverished regions

Proportion of children who qualify for protective drug treatment

 Diarrhea  Loss of appetite  Malaise  Intestinal obstructions  Initial itching or rash at the site of penetration  Intestinal bleeding leading to anemia and iron loss  Reduced absorption of micronutrients and proteins  Cognitive impairments and the stunting of growth

They average a length of µm.

Stool samples conducted over three consecutive days and plated on two different agar plates for prevalence measurements.

Eggs have an average length and width of µm by µm

 Albendazole  Mebendadole  Pyrantel pamoate  Iron supplements if anemic

 Multi-drug therapy to combat several STH  Preventative therapy for at risk communities  WHO recommends once a year treatment for communities with greater than 20% prevalence and twice a year for greater than 50%  More benefits in pregnancy than the alternative

 Knopp S, Mgeni AF, Khamis IS, Steinmann P, Stothard JR, et al. (2008) Diagnosis of Soil-Transmitted Helminths in the Era of Preventive Chemotherapy: Effect of Multiple Stool Sampling and Use of Different Diagnostic Techniques. PLoS Negl Trop Dis 2(11): e331. doi: /journal.pntd  Ndibazza J, Mpairwe H, Webb EL, Mawa PA, Nampijja M, Muhangi L, et al. Impact of anthelminthic treatment in pregnancy and childhood on immunisations, infections and eczema in childhood: a randomised controlled trial. PLoS One (2012) 7(12):e /journal.pone     