Table 7.1.1: Types of Tissue Allografts Supplied by USM Tissue Bank in 2007 Types of Tissue AllograftNo. (pieces) DF Femur2 DF Femoral head65 DF Humerus2 DF Tibia4 DF Radius0 DF Ulna0 FD Cancellous2 FD Cortical0 FD Cortico-cancellous0 Other FD Bones8 Patella2 Achilles2 Other tendon / fascia / cartilage3 Amniotic membranes175 TOTAL265 DF – Deep-frozen FD – Freeze-dried

Table 7.1.2: Hospitals/Other Sectors Using Bone/Tendon Allografts in 2007 USM Tissue Bank No. (pieces) Ministry of Health Hospitals Hospital Sultanah Aminah, Johor Bahru1 Hospital Melaka3 Hospital Pulau Pinang10 Hospital Raja Permaisuri Bainun, Ipoh3 Hospital Sultanah Bahiyah, Alor Setar2 Hospital Umum Sarawak, Kuching6 Queen Elizabeth Hospital, Kota Kinabalu2 TOTAL27 University Hospitals HUKM5 HUSM3 TOTAL8 Private and other sectors Amin Dental Surgery, Johor Bahru5 Chong Dental Surgery, Seri Kembangan Selangor1 Hospital Fatimah, Ipoh2 Hospital Sultan Ismail, Johor Bahru2 Hospital Tawakal, Kuala Lumpur3 Johnson & Johnson Medical2 Kemajuan Abadi Sdn. Bhd.2 Klinik Pergigian Chong, Tangkak, Johor1 Normah Medical Center, Kuching1 Stryker12 Zimmer21 TOTAL52

Table 7.1.3: Hospitals/Other Sectors Using Amniotic Membranes in 2007 USM Tissue Bank No. (pieces) Ministry of Health Hospitals Hospital Kuala Lumpur40 Hospital Sultan Ismail, Johor Bahru50 Hospital Miri, Sarawak5 Hospital Sultanah Bahiyah, Alor Setar7 Hospital Pulau Pinang3 Hospital Sultanah Nurzahirah, Kuala Terengganu5 Hospital Sungai Buloh, Selangor21 Hospital Teluk Intan, Perak4 Hospital Raja Perempuan Zainab II, Kota Bharu2 Hospital Umum Sarawak, Kuching6 Hospital Queen Elizabeth, Kota Kinabalu1 TOTAL144 University Hospitals HUKM7 HUSM7 IIUM6 TOTAL20 Private and other sectors Puteri Specialist Hospital, Johor Bahru5 ISEC Sdn. Bhd.2 Kuala Terengganu Specialist Center, Kuala Terengganu3 Putra Medical Centre, Alor Setar1 TOTAL11

Table 7.2.1: Distribution of Reporting Centre by Year Centre TOTAL No. Orthopaedics Department Department of Orthopaedics, HUSM Department of Orthopaedic Surgery, UMMC10001 Institute of Orthopaedics & Traumatology, HKL20002 Department of Orthopaedics, Hospital Ipoh01001 Department of Orthopaedics, Hospital Kota Bharu Department of Orthopaedics, Hospital Umum Sarawak10102 Department of Orthopaedics, Hospital Sultanah Aminah, Johor Bahru01001 Wan Orthopaedic, Trauma & Sports Injury Centre (WOTSIC), Seremban Specialist Hospital00202 Department of Orthopaedics, Hospital Island, Penang01001 Department of Orthopaedics, Hospital Fatimah, Ipoh03014 Department of Orthopaedics, Hospital Kuantan00011 Department of Orthopaedics, Kota Bharu Medical Centre00202 Department of Orthopaedics, Hospital Pulau Pinang00011 Normah Medical Specialist Centre, Kuching01001 Spine Unit, HUSM00101

Centre TOTAL No. Ophthalmology Department Department of Ophthalmology, Hospital Tengku Ampuan Rahimah, Klang11002 Department of Ophthalmology, Hospital Tengku Ampuan Afzan, Kuantan11002 Department of Ophthalmology, Hospital Teluk Intan00101 Department of Ophthalmology, HKL Department of Ophthalmology, Hospital Alor Setar00101 Department of Ophthalmology, Hospital Sungai Buloh00099 Department of Ophthalmology, Sri Kota Medical Centre01001 Department of Ophthalmology, HUSM00123 Others Department Maxillofacial Surgery, HUSM11002 Timberland Medical Centre01001 Sri Kota Medical Centre, Klang00101 Pantai Medical Centre, Kuala Lumpur00011 TOTAL

Table 7.3.1: Distribution of Patients by Gender Gender TOTAL No.% % % % % Male Female TOTAL Table 7.3.2: Distribution of Patients by Ethnic Group Ethnic Group TOTAL No.% % % % % Malay Chinese Indian Bumiputra Sabah Bumiputra Sarawak Others TOTAL Table 7.3.3: Distribution of Patients by Age Group

Age Group TOTAL No.% % % % % ≥ Missing TOTAL Mean SD Median Min Max Table 7.3.3: Distribution of Patients by Age Group

Table 7.3.4: Distribution of Patients by Diagnosis Warranting Tissue Graft Transplantation Diagnosis TOTAL No.% % % % % Congenital deformity Infection Trauma Degenerative disease Tumour-benign Tumour-malignant Burn Scald Sports injury Failed primary surgery Ophthalmological Others TOTAL Note: 5 patients with 2 diagnosis and 2 missing diagnosis.

Table 7.4.1: Distribution of Patients According to Tissue Provider Name Tissue Bank TOTAL No.% % % % % USM Tissue Bank Bone Bank, UMMC Bone Bank, HKL Eucara Pharmaceutical Osteo Tech Inc Missing TOTAL Table 7.4.2: Distribution of Patients by Origin of Tissue Graft Origin of Tissue Graft TOTAL No.% % % % % Local Imported Missing TOTAL

Table 7.4.3: Distribution of Tissue Graft Used by Type Tissue Graft Type TOTAL No.% % % % % Deep-frozen tissues Femur Femoral Head Humerus Tibia Radius Freeze-dried/ Air-dried Amniotic membranes Not Available Missing TOTAL Table 7.4.4: Distribution of Type of Sterilisation of the Graft Type Graft Sterilisation TOTAL No.% % % % % Gamma Irradiation Glycerol Sterile Freeze Dried Bone Missing TOTAL

Table 7.4.5: Distribution of Mode of Transport Storage to Recipient Hospital during Transportation Mode of Transport Storage to recipient hospital TOTAL No.% % % % % By Flight By Courier By Hand Dry Ice Box Sterile package Missing TOTAL Table 7.4.6: Distribution of Temperature of Storage during Transportation Temperature of storage during transportation ( o C) TOTAL No.% % % % % Room Temperature Missing TOTAL

Table 7.5.1: Distribution of Mode of Storage in Recipient Hospitals Mode of storage in recipient hospital TOTAL No.% % % % % Refrigerator Deep freezer-20 o C Deep freezer-40 o C Deep freezer-80 o C Glycerol Room temperature Others Not available Missing TOTAL Table 7.5.2: Distribution of Additional Tissue Usage (Composite Graft) Additional tissue usage (composite graft) TOTAL No.% % % % % No Yes Not available Missing TOTAL

Table 7.5.3: Distribution of Type of Additional Tissue Used (Composite Graft) Type of additional tissue used (composite graft) TOTAL No.% % % % % Autografts Allografts Others Missing TOTAL Table 7.5.4: Distribution of Presence of Pre Operative Infection at Implant Site Presence of pre operative infection at implant site TOTAL No.% % % % % No Yes Not Available Missing TOTAL Table 7.5.5: Distribution of Pre Implant Graft Culture Swab Pre implant graft culture swab TOTAL No.% % % % % No Yes Not Available Missing TOTAL

Table 7.5.6: Distribution of Type of Infection of Pre Implant Graft Type of infection of pre implant graft TOTAL No.% % % % % Cytomegalovirus Proteus TOTAL Table 7.5.7: Distribution of Grafts Soaked in Antibiotics Prior to Transplantation Grafts soaked in antibiotics prior to transplantation TOTAL No.% % % % % No Yes Not Available Missing TOTAL Table 7.5.8: Distribution of Antibiotics Used to Soak the Grafts in Prior to Transplantation Antibiotics used to soak the grafts in prior to transplantation TOTAL No.% % % % % Ceftriazone Gentamycin Ceftriazone and Gentamycin Vancomycin, Postome iodine Povidone iodine, Ceftriazone Missing TOTAL

Table 7.5.9: Distribution of Patients by Systemic Antibiotics Given Prior to Transplantation Systemic antibiotics prior to transplantation TOTAL No.% % % % % No Yes Not Available Missing TOTAL Table : Distribution of Patients by Type of Systemic Antibiotics Given Prior to Transplantation Type of systemic antibiotics given to patient prior to transplantation TOTAL No.% % % % % Cefeperazone Ceftriazone Cefuroxine Ciproflaxacin Chloramphenicol Metronidazole Ceftazidine Ceftriazone/Imipenam Ampicillin/Sulbactam T. Augmentin T. Flurariazole Missing TOTAL