Guideline for ClinLabGeneticist tool Jinlian Wang

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Presentation transcript:

Guideline for ClinLabGeneticist tool Jinlian Wang

1. Download

Unzip and “Install” Make sure ClinLabGeneticist and wes.accdb in the same folder. Otherwise, the tool can not work

Double click “ClinLabGeneticist1.9Beta.exe” to start installation Click ‘Next’

Installation path selection You can use the default directory and click”Next”

Installing…

Installation done Installed successfully. Click “Close” After ‘Close’, please check your desktop

Sign in User name is gmail Default password is CLG4reviewer Pull down the menu and select Reviewer Click ‘Sign in’

Reviewer Panel Click and Start reviewing your assignments Your Reviewed Assignments Browse Exit Click this to change your password

Assignments interface New assignment Not completed assignment Click to start review If your assignment is not submitted, the status is ‘Modified’

Reviewer’s master table Save your assignment Export assignment to excel Go Home Click ‘Next’ to submit your assignment

What does the master table function ? Master table help you to diagnose each variants & make decision based on some evidence. Check the detailed position information and structure of the variants through UCSC Genome browser. Look at the latest publication for each variants Review the pathogenic information of each variants from HGMD, OMIM, GeneCard, ClinVar at both gene and variants levels Provide population frequency information for each variants from ESP6500, 1k genomes. Allow you to check the detailed information of each variants though embedded IGV browser. Comment with your expertise opinion on each variants. Auto save the assignments every five minutes Export your assignments in the format of excel. Master table help you to diagnose each variants & make decision based on some evidence. Check the detailed position information and structure of the variants through UCSC Genome browser. Look at the latest publication for each variants Review the pathogenic information of each variants from HGMD, OMIM, GeneCard, ClinVar at both gene and variants levels Provide population frequency information for each variants from ESP6500, 1k genomes. Allow you to check the detailed information of each variants though embedded IGV browser. Comment with your expertise opinion on each variants. Auto save the assignments every five minutes Export your assignments in the format of excel.

Functions include: 1) sort : click small triangle in the header of each column 2) adjust the width of each column same as excel 3) freeze column: select the column you want to freeze, right click the header, and put your mouse within the popup window, 4) Hide column: same as 3), check the column you want to hide, 5) Comments: right click the cell you want to add comments, once the color is blue indicating the cell selected and you can make comments. Right click the cell to add comments Right click the header to Freeze/add /remove columns Auto save Mouse over each cell show the out sourced link Small icon indicates the comment made Click the header to sort each column

Submission Conform your submission Click ‘Next’ to submit your assignment Export your assignment to excel

Exported excel file

Submitted successfully Submitted successfully, a will automatically send to administrator

History browse Click to browse the history

Comments and Feedback Please contact me if you need source code Please give me your comments and suggestion by