Risk of GI Bleed on NSAIDs Professor Michael Langman International Ibuprofen Foundation University of Birmingham, UK.

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Presentation transcript:

Risk of GI Bleed on NSAIDs Professor Michael Langman International Ibuprofen Foundation University of Birmingham, UK

Table 1 Case Characteristics of the Three Studies Statistic British Catalan Swedish # Cases/Controls 1131/ / /1137 Age (Mean  SD) 74 ± ± ±15.2 % Male/Female 56/44 69/31 53/47 % Hx UGI Problems

Odds Ratios (95% C.I.) According to Drug (Not Dose Restricted) Note: The upper 95% C.I. bound for Piroxicam is 21.8 ; the odds ratio for Keto is 34.9 with an upper 95% C.I. bound of

Odds Ratios (95% C.I.) According to Dose of Drug (mg) APAPDiclof.Ibu Note: Values exceeding 15 are truncated at 15 1

Odds Ratios (95% C.I.) According to Dose of Drug (mg) IndomethNaproxenPiroxicam Note: Values exceeding 15 are truncated at 15 1

Odds Ratios (95% C.I.) According to Dose of Drug (mg) APAPDiclof.IbuIndomethNaproxenPiroxicam Note: Values exceeding 15 are truncated at 15 1