Title: Dual-Modality PET and Optical Imaging of CD105 Expression in Breast Cancer Authors: Yin Zhang, Hao Hong, Yunan Yang, Jonathan Engle, Charles Theuer,

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سرطان الثدي Breast Cancer

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Title: Dual-Modality PET and Optical Imaging of CD105 Expression in Breast Cancer Authors: Yin Zhang, Hao Hong, Yunan Yang, Jonathan Engle, Charles Theuer, Todd Barnhart, Weibo Cai Institution: University of Wisconsin - Madison Abstract #: 70 Session: RPSC Young Investigator Award Symposium (June 10, 2012 from 4:15 PM to 5:45 PM) Madison, WI, USA

CD105/Endoglin Expression in Solid Tumors CD105 is selectively expressed on proliferating endothelial cells at very high levels (up to 3×10 6 copies per cell) TRC105 is a human/murine chimeric IgG1 monoclonal antibody that binds to both human and murine CD105

FACS Analysis of 64 Cu-NOTA-TRC CW Zhang Y, Hong H, et al., Mol Pharm, 2012.

In Vivo PET and Optical Imaging Zhang Y, Hong H, et al., Mol Pharm, PET Optical 4T1 Breast Cancer Model

Zhang Y, Hong H, et al., Mol Pharm, Optical PET T: Tumor L1: Liver Ex Vivo PET and Optical Imaging