Supplementary table 2. Genes upregulated in both microarray and RNA-seq analysis Gene IDGene SymbolGenBank accesion no.Microarray FCP.ValueRNA-seq FCTM/SP.

Slides:



Advertisements
Similar presentations
How drugs act: Molecular aspects M.Sc. In Pharm (Pharmacology)
Advertisements

Fc Receptors Oct. 28, 2009 Extra reading on web Daniel Conrad 423 MSB, I. CD23.
Fig Simplified drawing of a cross-section through part of the wall of the intestine. Each tissue is an organized assembly of cells held together.
Cell-to-Cell and Cell-to-Matrix Adhesions
The Extracellular Matrix Michael Malahy. ECM in Epithelial Sheets 3 types of molecules abundant in ECM Proteoglycans Cushion cells and bind extracellular.
Extracellular Matrix Cell Biology Lecture 11.
Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Cell-Cell Interactions Chapter 7 Copyright © McGraw-Hill Companies Permission.
CHAPTER 9 LECTURE SLIDES
Cell Communication Chapter 9. 2 Fig Fig. 9.2.
Chapter 19: Cell junctions and the extracellular matrix
Last Class 1. ECM components: glycosaminoglycans (GAGs) and fibrous proteins a. GAGs: Hyaluronan; Chondroitin sulfate and dermatan sulfate; Heparan sulfate;
Ion Channels. Cell membrane Voltage-gated Ion Channels voltage-gated because they open and close depending on the electrical potential across the membrane.
Review Lecture II. 3 pathways to degradation in the lysosome.
Multiple Types of Epithelia. Structure of the Intestinal Epithelial Cell.
CELL RECEPTORS AND SIGNALLING By Phil and Alex. Basics Signalling controls all aspects of cell behaviour: Growth Differentiation Metabolism 3 main types.
CELL SIGNALING. THREE LEVELS OF CONTACT WITH ENVIRONMENT.
Cell membranes, Membrane lipids, Membrane proteins.
Function Enrichment Score Enrichment p- value % genes in group that are present # genes in list, in group type I interferon-mediated signaling pathway E
BIOCHEMICAL REGULATION (2) DR SAMEER FATANI. Energetics of membrane transport systems the change in free energy when an unchanged molecules Moves from.
Chapter 17 Beyond the Cell: Extracellular Structures, Cell Adhesion, and Cell Junctions.
hypothetical protein LOC554226LOC _at neurotrophic tyrosine kinase, receptor, type 3NTRK _s_at nuclear receptor.
Gene SymbolGene Name Fold Difference 1 q-value (%) 2 NL BM? 3 NR2F1nuclear receptor subfamily 2, group F, member No SLC2A10solute carrier family.
A b Cell Cycle c Proliferation KINASE A ANCHOR PROTEIN CASPASE 3, APOPTOSIS-RELATED CYSTEINE PROTEASE NUCLEAR RECEPTOR SUBFAMILY 3, GROUP C, MEMBER 1 BRUTON’S.
Passive vs. active transport Passive transport is simply transport down an electrochemical gradient until equilibrium is reached Active transport results.
There are four main types of membrane proteins:- Transporters – these help the passage of ions, sugars, amino acids, nucleotides and many other metabolites.
Active Transport, Transmembrane Proteins, and Neurons AP Biology 2006.
ADAM introduction Nan Song 2004/3/20. ADAM Contain: A Disintegrin And Metalloprotease Domain Other names: –Cellular disintegrins –MDCs (metalloprotease/
AP Biology Cell Junctions and Cell Communication Where cells touch each other…
Probe set Gene SymbolGene TitleRefSeq Transcript IDp-value Fold- Change _atIL7Rinterleukin 7 receptorNM_ _atCD28CD28 molecule.
Interaction of Cells with Other Cells (5)
Membrane Structure and Function Ch 12, Stryer Short Course.
Cell Junctions, Cell Adhesion, and the Extracellular Matrix.
© 2012 Pearson Education, Inc. Lectures by Kathleen Fitzpatrick Simon Fraser University Membranes: Their Structure, Function, and Chemistry Chapter 7.
Cell Communication Chapter Cell Communication: An Overview  Cells communicate with one another through Direct channels of communication Specific.
Cell Communication Chapter 9.
Signaling Machinery The Signals The Receivers
Lecture #5 Membrane Transport & Cell Communication.
Cell Communication Chapter 9.
NC-1 NC-2 NC-3 NC-4 NC-5 NC-6 NC-7 NC-8 NC-9 NC-10 NC-11 IN-1 IN-2 IN-3 IN-4 IN-5 IN-7 IN-8 IN-11 IN-12 IN-14 IN-16 AS-1 AS-7 AS-20 AS-21 AS-29 AS-32 AS-33.
Chapter 15- Cell Communication Part I- General signaling strategies
Specific Defenses of the Host Part 2 (acquired or adaptive immunity)
Interesting facts about cell and cell membrane:  Scientists estimate that our bodies contain anywhere from 75 to 100 trillion cells, all work in perfect.
Cell Communication Chapter 9. 2 Cell Communication Communication between cells requires: ligand: the signaling molecule receptor protein: the molecule.
Transduction of Extracellular Signals Specific receptors in plasma membranes respond to external chemicals (ligands) that cannot cross the membrane: hormones,
AH BIOLOGY: CELLS AND PROTEINS- PPT 6 MEMBRANE PROTEINS: CHANNEL AND TRANSPORT PROTEINS.
Table S10. A set of 140 Genes differentiating DF vs DHF (HG-U133 plus2 platform) Probeset IDGene SymbolGene Title p-value(DF vs. DHF) Fold- Change(DF vs.
Table S4. List of genes significantly changed in late acute phase vs convalescent phase (HG-focus platform) Probeset IDGene SymbolGene Titlep-valueFold-Change.
Supp table 1: Gene sets differentially expressed in Angpt-1 high MDS samples No.Gene Set NameGenes 1KEGG_CELL_CYCLE cyclin-dependent kinase 1, E2F transcription.
Mechanisms of Cell Communication
Immune Receptors and Signal Transduction
Integrin signalling Vytášek 2010.
ANIMAL CELL CULTURE.
Tissue repair (2 of 4) Ali Al Khader, M.D. Faculty of Medicine
Suraneni et al, table S7: Representative genes commonly upregulated in young transgenic (fl26y and svb9y) and old wt (wto) VPs compared to young wt (wty)
Cell to Cell Junctions and Adhesion
Supplementary Table. Gene expression profiling reveals a decrease in NFkB-driven gene signature pattern upon treatment with MLN4924. Gene ID Name Treated/
Embryologic outcome and secretome profile of implanted blastocysts obtained after coculture in human endometrial epithelial cells versus the sequential.
Cell Communication.
Signaling Machinery The Signals The Receivers
Cell to Cell Communication via Enzyme Linked Receptors
Cells into Tissues By Kevin Huyen.
Cell Communication Chapter 6.
Integrin signalling Vytášek 2009.
دکتر مجیری داروساز متخصص فارماکولوژی
Cell to Cell Communication
Chapter 19: Cell junctions and the extracellular matrix Know the terminology: Cadherins, integrins, tight junction, desmosome, adhesion belt, hemidesmosome,
Crystal Aguh, MD, Yemisi Dina, BS, C
Supplementary Table 2. List of downregulated genes by PAUF **
Fig. 1. Summary of AERD associated single nucleotide polymorphisms in the genes of immune response and arachidonate pathway. OR, odds ratio; Ref, reference.
Presentation transcript:

Supplementary table 2. Genes upregulated in both microarray and RNA-seq analysis Gene IDGene SymbolGenBank accesion no.Microarray FCP.ValueRNA-seq FCTM/SP Six Transmembrane Epithelial Antigen Of The Prostate 1STEAP1NM_ Carbonic Anhydrase IxCA9NM_ Eph Receptor B2EPHB2NM_ Solute Carrier Family 39 (Zinc Transporter), Member 4SLC39A4NM_ Udp Glycosyltransferase 8UGT8NM_ Protocadherin 7PCDH7NM_ Serine Incorporator 2SERINC2NM_ Lysophosphatidic Acid Receptor 2LPAR2NM_ Matrix Metallopeptidase 14 (Membrane-Inserted)MMP14NM_ Steap Family Member 3, MetalloreductaseSTEAP3NM_ Proteolipid Protein 2 (Colonic Epithelium- Enriched)PLP2NM_ Transmembrane Protease, Serine 4TMPRSS4NM_ Ring Finger Protein 43RNF43NM_ Shisa Homolog 2 (Xenopus Laevis)SHISA2NM_ Desmocollin 2DSC2NM_ Prostaglandin F2 Receptor Negative RegulatorPTGFRNNM_ Endothelin Converting Enzyme 2ECE2NM_ Atp-Binding Cassette, Sub-Family C (Cftr/Mrp), Member 3ABCC3NM_ Atp-Binding Cassette, Sub-Family A (Abc1), Member 1ABCA1NM_ Solute Carrier Family 39 (Metal Ion Transporter), Member 11SLC39A11NM_ Integrin, Alpha 11ITGA11NM_ Fibroblast Activation Protein, AlphaFAPNM_ Bmp And Activin Membrane-Bound Inhibitor Homolog (Xenopus Laevis)BAMBINM_ Receptor Accessory Protein 4REEP4NM_ Slam Family Member 8SLAMF8NM_ Desmoglein 2DSG2NM_ Prominin 2PROM2NM_ Leucine-Rich Repeats And Immunoglobulin-Like Domains 3LRIG3NM_ Tenascin CTNCNM_ Semaphorin 4BSEMA4BNM_ Asparagine-Linked Glycosylation 3ALG3NM_ Igf-Like Family Receptor 1IGFLR1NM_ Opioid Receptor, Kappa 1OPRK1NM_ Sodium Channel, Voltage-Gated, Type Ix, Alpha SubunitSCN9ANM_ Coagulation Factor Ii (Thrombin) Receptor-Like 1F2RL1NM_ Plexin Domain Containing 1PLXDC1 (TEM7)NM_ Solute Carrier Family 39 (Zinc Transporter), Member 6SLC39A6NM_ Leukocyte Immunoglobulin-Like Receptor, Subfamily B Member 4LILRB4NM_ Elovl Fatty Acid Elongase 6ELOVL6NM_ Serine Peptidase Inhibitor, Kunitz Type, 2SPINT2NM_ Protease, Serine, 16 (Thymus)PRSS16NM_

Supplementary table 2. Continued Gene IDGene SymbolGenBank accesion no.Microarray FCP.ValueRNA-seq FCTM/SP Cklf-Like Marvel Transmembrane Domain Containing 7CMTM7NM_ Aspartate Beta-HydroxylaseASPHNM_ Adam Metallopeptidase Domain 12ADAM12NM_ Heparin-Binding Egf-Like Growth FactorHBEGFNM_ Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8SLC6A8NM_ Transmembrane Protein 116TMEM116NM_ Sphingosine-1-Phosphate Receptor 3S1PR3NM_ Glycosyltransferase-Like 1BGYLTL1BNM_ Perp, Tp53 Apoptosis EffectorPERPNM_ Transmembrane Emp24 Protein Transport Domain Containing 3TMED3NM_ Trophoblast GlycoproteinTPBGNM_ Sodium Channel, Nonvoltage-Gated 1 AlphaSCNN1ANM_ Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2KCNJ2NM_ Claudin 4CLDN4NM_ Claudin 7CLDN7NM_ G Protein-Coupled Receptor 98GPR98NM_ Nadph Oxidase 4NOX4NM_ Wingless-Type Mmtv Integration Site Family, Member 5AWNT5ANM_ Sphingosine-1-Phosphate Phosphatase 2SGPP2NM_ Fxyd Domain Containing Ion Transport Regulator 3FXYD3NM_ Solute Carrier Family 7 (Anionic Amino Acid Transporter Light Chain, Xc- System), Member 11SLC7A11NM_ Retinol Dehydrogenase 10 (All-Trans)RDH10NM_ Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1SLC2A1NM_ Chemokine (C-X-C Motif) Receptor 7CXCR7NM_ Uroplakin 1BUPK1BNM_ Fatty Acid 2-HydroxylaseFA2HNM_ Hyaluronan Synthase 3HAS3NM_ Transmembrane Protein 54TMEM54NM_ Solute Carrier Family 7 (Amino Acid Transporter Light Chain, L System), Member 5SLC7A5NM_ Egf-Like, Fibronectin Type Iii And Laminin G DomainsEGFLAMNM_ Xk, Kell Blood Group Complex Subunit-Related, X- LinkedXKRXNM_ Solute Carrier Family 38, Member 1SLC38A1NM_ Carbonic Anhydrase XiiCA12NM_ Wap Four-Disulfide Core Domain 2WFDC2NM_ Cadherin 1, Type 1, E-Cadherin (Epithelial)CDH1NM_ Claudin 1CLDN1NM_ Solute Carrier Organic Anion Transporter Family, Member 4C1SLCO4C1NM_ Cytochrome P450, Family 4, Subfamily F, Polypeptide 3CYP4F3NM_ Gap Junction Protein, Beta 5, 31.1KdaGJB5NM_ Peptidase Inhibitor 3, Skin-DerivedPI3NM_

Supplementary table 2. Continued Gene IDGene SymbolGenBank accesion no.Microarray FCP.ValueRNA-seq FCTM/SP Cd24 MoleculeCD24NM_ Lemur Tyrosine Kinase 3LMTK3NM_ Collagen, Type Xvii, Alpha 1COL17A1NM_ Transient Receptor Potential Cation Channel, Subfamily V, Member 4TRPV4NM_ Coxsackie Virus And Adenovirus ReceptorCXADRNM_ Golgi Membrane Protein 1GOLM1NM_ Chloride Channel Accessory 2CLCA2NM_ Atpase, Na+/K+ Transporting, Beta 1 PolypeptideATP1B1NM_ Mal, T-Cell Differentiation Protein 2 (Gene/Pseudogene)MAL2NM_ Tumor-Associated Calcium Signal Transducer 2TACSTD2NM_ Desmocollin 3DSC3NM_ Sidekick Homolog 1, Cell Adhesion Molecule (Chicken)SDK1NM_ Junctophilin 1JPH1NM_ Coagulation Factor Iii (Thromboplastin, Tissue Factor)F3NM_ Chemokine (C-X-C Motif) Ligand 9CXCL9NM_ Mucin 4, Cell Surface AssociatedMUC4NM_ Neuromedin BNMBNM_ Myelin Protein Zero-Like 2MPZL2NM_ Glucagon ReceptorGCGRNM_ Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 13SERPINB13NM_ Solute Carrier Family 6 (Amino Acid Transporter), Member 14SLC6A14NM_ Cadherin, Egf Lag Seven-Pass G-Type Receptor 1 (Flamingo Homolog, Drosophila)CELSR1NM_ Fibroblast Growth Factor Receptor 2FGFR2NM_ Protein Tyrosine Phosphatase, Receptor-Type, Z Polypeptide 1PTPRZ1NM_ Pdzk1 Interacting Protein 1PDZK1IP1NM_ Interleukin 8IL8ENST Scavenger Receptor Class A, Member 3SCARA3NM_ PodoplaninPDPNNM_ Atpase, Ca++ Transporting, Type 2C, Member 2ATP2C2NM_ Major Facilitator Superfamily Domain Containing 2AMFSD2ANM_ Parathyroid Hormone 2 ReceptorPTH2RNM_ C-Ros Oncogene 1, Receptor Tyrosine KinaseROS1ENST Adam Metallopeptidase Domain 23ADAM23NM_ Cadherin 26CDH26NM_ Integrin, Beta 6ITGB6NM_ Keratinocyte Associated Protein 3KRTCAP3NM_ Vascular Cell Adhesion Molecule 1VCAM1NM_ Herv-H Ltr-Associating 2HHLA2NM_ Family With Sequence Similarity 20, Member AFAM20ANM_ Solute Carrier Family 26, Member 9SLC26A9NM_ Mucin 1, Cell Surface AssociatedMUC1NM_