Location: Brain – at the bottom of the third ventricle Tissue Type: Neural Hormone: - Gonadotropin Releasing Hormone (GnRH) - Oxytocin Target Organ/Structure(s): Pituitary Glands
Two Parts: - Anterior - Posterior
Location: Base of the brain; above the roof of the mouth Tissue Type: Oral Ectoderm Hormone(s): - Follicle Stimulating Hormone (FSH) - Luteinizing Hormone (LH) Target Organ/Structure(s): Ovary
Location: Base of brain, under the hypothalamus, behind the anterior pituitary Tissue Type: Neural Hormone(s): - Oxytocin (released from PP) Target Organ/Structure(s): - Mammary Gland (myoendothelial cell) - Myometrium
Location: Lower abdomen Tissue Type: Glandular/Gonadal Hormone(s): - Estrogen Endocrine Structure: Follicle Target Organ/Structure(s): Hypothalamus Function: Increase GnRH - Progesterone Endocrine Structure: Corpus Luteum Target Organ/Structure(s): Hypothalamus Function: Decrease GnRH
Hormone: - Prostaglandin F2α Target Organ/Structure: Ovary, specifically the corpus luteum Function: Lyses it, to restart cycle when no maternal recognition of pregnancy (MRP) occurs (no fertilized ova in uterus)
What are the two cycle types ?: 1) Menstrual 2) Estrus Why two different names?
Menstrual = is calculated from menses to menses, ovulation occurs in the middle of the cycle. (it is what we can see!; humans, primates, etc.) Estrus = is calculated from standing heat to standing heat, ovulation occurs 36 hours later (it is what we can see!; domestic animals)
HYPOTHALAMUS
GONADOTROPIN RELEASING HORMONE
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH OVARY
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH OVARY FOLLICLE
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH OVARY FOLLICLE ESTROGEN
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH OVARY FOLLICLE ESTROGEN MORE!! + +
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH OVARY FOLLICLE ESTROGEN MORE!! + +
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY FOLLICLE ESTROGEN MORE!! + +
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY FOLLICLE ESTROGEN MORE!! + + (Surge Release)
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY OVULATION (Surge Release) OVA Down Oviduct
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE LESS!! - -
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE LESS!! - - MRP UTERUS
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE LESS!! - - MRP UTERUS
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE LESS!! - - NO!!!! MRP UTERUS
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE LESS!! - - NO!!!! MRP UTERUS PROSTAGLANDIN F2α
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE LESS!! - - NO!!!! MRP UTERUS PROSTAGLANDIN F2α
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH OVARY FOLLICLE ESTROGEN MORE!! + +
ESTROGEN
LUTEINIZING HORMONE
ESTROGEN LUTEINIZING HORMONE
ESTROGEN LUTEINIZING HORMONE PROGESTERONE
Location: Brain – at the bottom of the third ventricle Tissue Type: Neural Hormone: - Gonadotropin Releasing Hormone (GnRH) - Oxytocin Target Organ/Structure(s): Pituitary Glands
Two Parts: - Anterior - Posterior
Location: Base of the brain; above the roof of the mouth Tissue Type: Oral Ectoderm Hormone(s): - Follicle Stimulating Hormone (FSH) - Luteinizing Hormone (LH) Target Organ/Structure(s): Ovary
Location: Base of brain, under the hypothalamus, behind the anterior pituitary Tissue Type: Neural Hormone(s): - Oxytocin (released from PP) Target Organ/Structure(s): - Sperm Transport
Location: Scrotum/abdomen - varies Tissue Type: Glandular/Gonadal Hormone(s): - Estrogen Endocrine Structure: Sertoli Cell Target Organ/Structure(s): Hypothalamus Function: Increase GnRH - Testosterone Endocrine Structure: Leydig cell Target Organ/Structure(s): Sertoli Cell Function: Secrete nutrients for sperm
HYPOTHALAMUS
GONADOTROPIN RELEASING HORMONE
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH Leydig Cells Basement Membrane Sertoli Cells Sperm
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH ESTROGEN Leydig Cells Basement Membrane Sertoli Cells Sperm
HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH ESTROGEN MORE!! + + Leydig Cells Basement Membrane Sertoli Cells Sperm
Test LH Into Blood Nutrients FSH Estrogen Testosterone
The ULTIMATE nuclear weapon. Produced: Testes Stored: Caudal Epididymis Accessory Glands: Function: Provide nutrients for the sperm Anatomy:
Cholesterol -Pregnenolone -Progesterone -17α OH Progesterone -Testosterone Estrogen
SPECIECYCLE LENGTH GESTATION Human28 days9 mo. Cow21285 days Sheep17147 Pig21114 Goat21150 Horse22336
1) Facilitate A.I. 2) Intensify A.I 3) Efficient use of labor 4) Heat detection efficiency 5) Earlier pregnancy 6) Shorter breeding period 7) Sell uniform calves 8) E.T. program
- Prostaglandin - Progesterone - GnRH
MGA = Melengesterol Acetate (progesterone) added to feed
Controlled Internal Drug-Releasing insert
Gonadotropin releasing hormone – causes ovulation via LH surge
Primary: Standing to be mounted Secondary: Aids:
Primary: Standing to be mounted Secondary: Mounting other cows; red vulva; Mucous discharge; restless, excitable, bawling Aids: Kamar, Tail paint; Chin Marker, Heat watch
Storage › Semen Tank (-320 F) › Extenders, Milk or Yolk, and Glycerol (cryopreservent) › 6 ml semen in ejaculate › 1.5 billion sperm/ml › Want million sperm/straw
Thaw › F in water › 30 – 40 seconds › Dry off straw › Put in gun › Sheath › Cover, put in pants
Deposition › Insert A.I. gun at 45 degree angle Be cautious of urethra and bladder › Feed gun through cervix › 5 second deposition
Donor = Eggs Recipient = Gestation Superovulation: › Hormone: Follicle Stimulating Hormone › Atresia versus recruitment
Recipient – Synchronization › Within 24 hours of donor Flushing › Saline Solution Implanting › A.I. Gun