Location: Brain – at the bottom of the third ventricle Tissue Type: Neural Hormone: - Gonadotropin Releasing Hormone (GnRH) - Oxytocin Target Organ/Structure(s):

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Presentation transcript:

Location: Brain – at the bottom of the third ventricle Tissue Type: Neural Hormone: - Gonadotropin Releasing Hormone (GnRH) - Oxytocin Target Organ/Structure(s): Pituitary Glands

Two Parts: - Anterior - Posterior

Location: Base of the brain; above the roof of the mouth Tissue Type: Oral Ectoderm Hormone(s): - Follicle Stimulating Hormone (FSH) - Luteinizing Hormone (LH) Target Organ/Structure(s): Ovary

Location: Base of brain, under the hypothalamus, behind the anterior pituitary Tissue Type: Neural Hormone(s): - Oxytocin (released from PP) Target Organ/Structure(s): - Mammary Gland (myoendothelial cell) - Myometrium

Location: Lower abdomen Tissue Type: Glandular/Gonadal Hormone(s): - Estrogen Endocrine Structure: Follicle Target Organ/Structure(s): Hypothalamus Function: Increase GnRH - Progesterone Endocrine Structure: Corpus Luteum Target Organ/Structure(s): Hypothalamus Function: Decrease GnRH

Hormone: - Prostaglandin F2α Target Organ/Structure: Ovary, specifically the corpus luteum Function: Lyses it, to restart cycle when no maternal recognition of pregnancy (MRP) occurs (no fertilized ova in uterus)

What are the two cycle types ?: 1) Menstrual 2) Estrus Why two different names?

Menstrual = is calculated from menses to menses, ovulation occurs in the middle of the cycle. (it is what we can see!; humans, primates, etc.) Estrus = is calculated from standing heat to standing heat, ovulation occurs 36 hours later (it is what we can see!; domestic animals)

HYPOTHALAMUS

GONADOTROPIN RELEASING HORMONE

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH OVARY

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH OVARY FOLLICLE

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH OVARY FOLLICLE ESTROGEN

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH OVARY FOLLICLE ESTROGEN MORE!! + +

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH OVARY FOLLICLE ESTROGEN MORE!! + +

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY FOLLICLE ESTROGEN MORE!! + +

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY FOLLICLE ESTROGEN MORE!! + + (Surge Release)

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY OVULATION (Surge Release) OVA Down Oviduct

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE LESS!! - -

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE LESS!! - - MRP UTERUS

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE LESS!! - - MRP UTERUS

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE LESS!! - - NO!!!! MRP UTERUS

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE LESS!! - - NO!!!! MRP UTERUS PROSTAGLANDIN F2α

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSHLH OVARY CORPUS LUTEUM PROGESTERONE LESS!! - - NO!!!! MRP UTERUS PROSTAGLANDIN F2α

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH OVARY FOLLICLE ESTROGEN MORE!! + +

ESTROGEN

LUTEINIZING HORMONE

ESTROGEN LUTEINIZING HORMONE

ESTROGEN LUTEINIZING HORMONE PROGESTERONE

Location: Brain – at the bottom of the third ventricle Tissue Type: Neural Hormone: - Gonadotropin Releasing Hormone (GnRH) - Oxytocin Target Organ/Structure(s): Pituitary Glands

Two Parts: - Anterior - Posterior

Location: Base of the brain; above the roof of the mouth Tissue Type: Oral Ectoderm Hormone(s): - Follicle Stimulating Hormone (FSH) - Luteinizing Hormone (LH) Target Organ/Structure(s): Ovary

Location: Base of brain, under the hypothalamus, behind the anterior pituitary Tissue Type: Neural Hormone(s): - Oxytocin (released from PP) Target Organ/Structure(s): - Sperm Transport

Location: Scrotum/abdomen - varies Tissue Type: Glandular/Gonadal Hormone(s): - Estrogen Endocrine Structure: Sertoli Cell Target Organ/Structure(s): Hypothalamus Function: Increase GnRH - Testosterone Endocrine Structure: Leydig cell Target Organ/Structure(s): Sertoli Cell Function: Secrete nutrients for sperm

HYPOTHALAMUS

GONADOTROPIN RELEASING HORMONE

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH Leydig Cells Basement Membrane Sertoli Cells Sperm

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH ESTROGEN Leydig Cells Basement Membrane Sertoli Cells Sperm

HYPOTHALAMUS GONADOTROPIN RELEASING HORMONE ANTERIOR PITUITARY FSH LH ESTROGEN MORE!! + + Leydig Cells Basement Membrane Sertoli Cells Sperm

Test LH Into Blood Nutrients FSH Estrogen Testosterone

The ULTIMATE nuclear weapon.  Produced: Testes  Stored: Caudal Epididymis  Accessory Glands:  Function: Provide nutrients for the sperm  Anatomy:

Cholesterol -Pregnenolone -Progesterone -17α OH Progesterone -Testosterone Estrogen

 SPECIECYCLE LENGTH GESTATION  Human28 days9 mo.  Cow21285 days  Sheep17147  Pig21114  Goat21150  Horse22336

1) Facilitate A.I. 2) Intensify A.I 3) Efficient use of labor 4) Heat detection efficiency 5) Earlier pregnancy 6) Shorter breeding period 7) Sell uniform calves 8) E.T. program

- Prostaglandin - Progesterone - GnRH

MGA = Melengesterol Acetate (progesterone) added to feed

Controlled Internal Drug-Releasing insert

Gonadotropin releasing hormone – causes ovulation via LH surge

Primary: Standing to be mounted Secondary: Aids:

Primary: Standing to be mounted Secondary: Mounting other cows; red vulva; Mucous discharge; restless, excitable, bawling Aids: Kamar, Tail paint; Chin Marker, Heat watch

 Storage › Semen Tank (-320 F) › Extenders, Milk or Yolk, and Glycerol (cryopreservent) › 6 ml semen in ejaculate › 1.5 billion sperm/ml › Want million sperm/straw

 Thaw › F in water › 30 – 40 seconds › Dry off straw › Put in gun › Sheath › Cover, put in pants

 Deposition › Insert A.I. gun at 45 degree angle  Be cautious of urethra and bladder › Feed gun through cervix › 5 second deposition

 Donor = Eggs  Recipient = Gestation  Superovulation: › Hormone: Follicle Stimulating Hormone › Atresia versus recruitment

 Recipient – Synchronization › Within 24 hours of donor  Flushing › Saline Solution  Implanting › A.I. Gun