GI System & Respiratory System EXAM REVIEW GI System & Respiratory System

HCl Production Key Info to Note: Parietal cells contain Carbonic Anhydrase (CAH) H+ pumped into stomach lumen by H-K ATPase HCO3- exchanged for Cl- (chloride shift) Alkaline tide in blood due to increase HCO3- (Increase pH)

Cl- Cl- K+ HCl HCO3- H+ CO2 CO2+H2OH2CO3 BLOOD PARIETAL CELL LUMEN OF STOMACH Cl- Cl- K+ HCl HCO3- H+ CO2 CO2+H2OH2CO3

Protein Digestion

Parietal Cell stimulated Pyloric Gland Gastric Gland Pepsinogen Food enters Stomach Secrete Gastrin Chief Cell stimulated G Cell Stimulated Gastric pH HCl Parietal Cell stimulated Partially digested protein Pepsin (Pepsinogen+HCl) = Parietal Cell = G Cell = Chief Cell

Fat Digestion

Gastric Motility Suppress GM? 1. 2. 3. Activate GM?

Pancreatic Enzymes Trypsinogen Chymotrypsinogen Precarboxypeptidase Enterokinase Trypsin Trypsin Chymotrypsin Trypsin Carboxypeptidase Others: Pancreatic Lipase Pancreatic Amylase

O2 Transport On your own time, define the following gas laws: HENRY’S BOYLE’S DALTON’S **Be able to relate these to respiration

Hemoglobin-O2 Curve Affinity Reduced: by LOW pH by HIGH temperature by HIGH CO2 concentration