Overview of The Immune System:

Slides:

Advertisements

Similar presentations

Lectures 1 & 2 The immune system Overview

Advertisements

HUMORAL AND CELL-MEDIATED IMMUNITY

Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc. Chapter 67 Review of the Immune System.

Lymphocyte development and survival Chapter 7. Objectives Describe or construct flow charts showing the stages in development of B cells and T cells,

Lecture outline The nomenclature of Immunology Types of immunity (innate and adaptive; active and passive; humoral and cell- mediated) Features of immune.

Lecture outline The nomenclature of Immunology

Topics The Ag-specific T cell receptor

Dental Microbiology #211 IMMUNOLOGY 2006 Lecture 2 The Lymphocytes.

Principles of Immunology Overview of Adaptive Immunity 1/24/06 “Too many people overvalue what they are not and undervalue what they are.” M Forbes.

Principles of Immunology Cells of the Immune System 1/26/06 “Those who have health, have hope. Those who have hope have everything.” Arabian proverb.

Cells and Organs of the Immune System Cells – Leukocytes a. Lymphocytes – specialized for adaptive immunity b. Granulocytes/Agranulocytes – func in accessory.

Cells of inflammation and Immunity G. Wharfe 2005.

Adaptive Defenses T Lymphocytes T lymphocytes constitute the "cellular" arm of acquired/specific immunity T lymphocytes play a central role in controlling.

Adaptive Immune System Chapter 16

Design of immune system Immune system Self/non-self recognition The state of protection from infectious disease 自我非我 Memory Acceptance vs rejection 疫苗.

Immunology ; “Science of Self/Non-self Discrimination”

Body’s Defenses. Passive Formation of antibodies To the fetus thru the placenta, thru breast milk, thru administration of plasma (artificial) Active.

Immunology: Innate Immunity

Adaptive Immunity: Specific Defenses of the host

Immune System “Do I still have to go to school doc?”

Podcasting is functional Extra slides Larger format slides.

Dental Microbiology #211 IMMUNOLOGY Lecture 5 Cellular Immunity: The functions of T cells.

Cell mediated response What the B-cells miss or are not programmed to deal with T-cells are able to handle. Usually 1.

The immune response White Blood cell types. Myeloid stem cells Lymphoid cells Pluripotent stem cells (in bone marrow) Monocyte Mast cells Basophils Neutrophils.

 To know the historical perspective of immunology  To be familiar with the basic terminology and definitions of immunology  Cells of immune response.

The Immune System 2 1. Adaptive Specific immunity (acquired) = the ability of the body to defend itself against specific invading agents such as bacteria,

Immune System Overview. GOT DEFENSE? ANATOMY OF THE IMMUNE SYSTEM The immune system is localized in several parts of the body –immune cells develop.

Dental Microbiology #211 IMMUNOLOGY Lecture 2. Topics The B and T Lymphocytes Antigen-specific Receptors on B and T cells CD4+ and CD8+ T cells Cytokines.

IMMUNOLOGY By ZOHA and SAMIHA.

Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings PowerPoint ® Lecture Slide Presentation prepared by Christine L. Case M I C R.

Myelopoiesis and Lymphopoiesis Amy Lovett-Racke, PhD Associate Professor Department of Microbial Infection and Immunity.

___________DEFENSES of the HOST: THE IMMUNE RESPONSE

Immunology B cells and Antibodies – humoral

ORGANIZATION OF THE IMMUNE SYSTEM different cell types diffuse communication network between cells ‚signal transduction’ and inhibition similarity to the.

Major Events in the Local Inflammatory Response.

Innate and adaptive immunity The immune system has various mechanisms to eliminate pathogens that get past physical barriers. These include both innate.

Ch 43 The Body’s Defense. Three lines of Defense: 1. External defenses 2. Internal (phagocytes, inflammation) 3. Specific defense: (lymphocytes) 1 & 2.

Therapies targeting the Immune System:  Stimulation  Suppression  Modulation.

GENERAL IMMUNOLOGY PHT 324

Immunology 오 상택.

Kuby Immunology, 7e: Chapter 2

Elements of the Immune System and their Roles in Defense

Medical Immunology.

Chapter 43 The Immune System.

GENERAL IMMUNOLOGY PHT 324

Immunology Lecture 4 Development of B and T lymphocytes

Immunity Ch Microbiology.

Concepts of Inflammation and the Immune Response

مكونات المناعة Components of Immunity

Chapter 18 Warm-Up Define the following terms:

CELL-MEDIATED IMMUNITY RAHUL KUMAR LOHANA 2K16/MB/50 INSTITUTE OF MICROBIOLOGY UNIVERSITY OF SINDH, JAMSHORO.

Chapter 14 Immune System.

Chapter 43 Warm-Up Define the following terms:

Chapter 43 Warm-Up Define the following terms:

Chapter 43 Warm-Up Define the following terms:

Ch 43 The Body’s Defense.

6.3 T cells and cell-mediated immunity

The Immune System Medical Foundations.

T cell mediated immunity

Chapter 43 Warm-Up Define the following terms:

Chapter 43 THE IMMUNE SYSTEM.

Cells & Organs of the immune system Dr. Mohed. Shaker

Chapter 43 Warm-Up Define the following terms:

CELLS INVOLVES IN IMMUNITY UTTARAN MODHUKALYA 1. CONTENT 1. INTRODUCTION 2. HEMATOPOIETIC STEM CELL 3. LYMPHOCYTE CELL 4. MYELOID CELL 5. REFERENCE 6.

Cellular and biochemical mediators of immune response By - (M-PHARM SEM-ii) Dept. of-PHARMACOLOGY.

Humoral and Cell Mediated Immunity

Adaptive (specific ) Immunity

Components of Acquired Immunity NISARG RAVAL. IMMUNE  WHAT IS IMMUNE SYSTEM? Immune system is remarkably versatile defense system. It is able to recognize.

Presentation transcript:

Overview of The Immune System:

Outline for Lectures 2 & 3 The immune system is designed to eliminate pathogens. Who are the infectious agents? Overview of the two arms of the immune system: innate immunity & adaptive immunity. What are the cell types involved with immune responses? What are the important immunological tissues?

How do pathogens enter into the human body? Parham, p. 3 How do pathogens enter into the human body? What barriers are present in the human body to prevent entry/infection by pathogens?

Would the immune response towards each type of pathogen be identical? Parham, p. 4

Innate Immunity Adaptive Immunity (acquired) Humoral immunity & Cell Mediated Immunity

Comparison of Innate Immunity to Adaptive Immunity Parham, P. 9

The relationship between innate & adaptive Immune responses:

The innate immune response is essential for elimination of a pathogen but not sufficient. The adaptive immune response requires certain key players of the innate immune response to become activated.

The components of the immune system Overview of Cell Types important in immunology

Where do the cells of the immune system come from? Leukocytes- Hematopoiesis: Hematopoietic stem cells from the bone marrow Undifferentiated Pluripotent Self-renewing

Progenitors: -Not self-renewing -Committed to differentiation Granulocyte/ macrophage progenitor

What stimulates the differentiation of stem cells & progenitor cells? Hematopoietic Inducing Microenvironment: Requires bone marrow stromal cells & growth factors (cytokines). Kuby, Immunology, fig. 2-2

The leukocytes (WBC) Kuby Immunology

The Cells Important in Immunology A Closer Look

Lymphocytes: B lymphocytes (B cells) T lymphocytes (T cells) Important for the adaptive immune response.

Surface receptor = Immunoglobulin (Ig). B cells: Surface receptor = Immunoglobulin (Ig). Humoral Immunity. kuby

T cells: Helper T cells (Th cells): Cytotoxic T cells (Tc or CTL): T cell Receptor (TCR) CD4+ Produce cytokines & direct immune responses. Cytotoxic T cells (Tc or CTL): TCR+ CD8+ Cytotoxic