Copyright © 2008 Lippincott Williams & Wilkins. Introductory Clinical Pharmacology Chapter 13 Leprostatic Drugs.

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Presentation transcript:

Copyright © 2008 Lippincott Williams & Wilkins. Introductory Clinical Pharmacology Chapter 13 Leprostatic Drugs

Copyright © 2008 Lippincott Williams & Wilkins. Introduction Chronic, communicable disease;long incubation period AKA “Hansen’s disease”: Caused by the bacterium Mycobacterium Peripheral nerves affected & skin lesions that are painful Leprostatic drugs: Help to control the disease; prevent complications

Copyright © 2008 Lippincott Williams & Wilkins. Medications to Recognize Dapsone clofazimine (Lamprene) rifampin ( Rifadin) ethionamide (Trecator)

Copyright © 2008 Lippincott Williams & Wilkins. Clofazimine Actions and uses –Has anti-inflammatory action; bactericidal against M. leprae –Action: Binds with DNA of mycobacterium, causing cell death –Use: Primary combined leprosy therapy; inflammation of nodular disease

Copyright © 2008 Lippincott Williams & Wilkins. Dapsone Actions and uses –Used to treat: Leprosy Dermatitis herpetiformis Chronic and inflammatory skin disease –Effective in prophylactic treatment of Pneumocystis carinii pneumonia

Copyright © 2008 Lippincott Williams & Wilkins. Nursing Process: The Patient Receiving a Leprostatic Drug – Assessment Preadministration assessment –Perform complete physical examination and history before the initiation of therapy –Examine areas and describe them in detail on the patient's record for comparison during therapy

Copyright © 2008 Lippincott Williams & Wilkins. Nursing Process: The Patient Receiving a Leprostatic Drug – Assessment (cont’d) Ongoing assessment –Drugs often given on outpatient basis –Perform general physical examination at every visit Pay particular attention to affected areas

Copyright © 2008 Lippincott Williams & Wilkins. Nursing Process: The Patient Receiving a Leprostatic Drug – Evaluation Therapeutic drug effect achieved Patient –Has resources to deal with body image changes –Verbalizes understanding of treatment modalities and importance of follow-up care –Demonstrates understanding of drug regimen –Complies with prescribed drug regimen

Copyright © 2008 Lippincott Williams & Wilkins. End of Presentation