Sanrio M. Canillo BBTE 2-1

Non-living fluid matrix plasma and formed elements Dull-red in color, depending on the amount of the oxygen carried Normal adult blood volume: 5 to 6 liters

Erythrocytes – Red Blood Cells Leukocytes – White Blood Cells

45 %of total blood volume Small biconcave disk shaped cell Contains HEMOGLOBIN 1 red blood cell = 250 Million hemoglobin molecule 1 hemoglobin molecule = 4 molecules of Oxygen Normal blood contains men: 14 to 18 g, women: 12 to 16 g

Body’s defense against diseases 4000 to WBC / cubic mm 1% of the total blood volume Forms a protective army that helps defend the body against damage by bacteria, viruses, parasites and tumor cells Capable to slip in and out of the blood vessel by the process of DIAPEDESIS

PASSIVE CHEMOTAXIS - WBC alarm system; process where leukocytes can locate areas of tissue damage and infection in the body by responding to certain chemicals that diffuse from the damaged cells. Leukocytosis - A condition wherein the total WBC count is over 11,000 / cubic mm. This generally indicates that a bacteria or viral infection is stewing in the body.

Leukopenia - a condition where there is an abnormally low WBC count, caused by the presence of certain drugs Leukemia - a condition where there is excessive production of abnormal WBC. Bone marrow becomes cancerous and a huge number of WBC are produced rapidly.

GRANULOCYTES – 65% of total WBC count; WBC with granules. 3 types: POLYMORPHONUCLEAR Leukocytes/ NEUTROPHILS EOSINOPHILS BASOPHILS

POLYMORPHONUCLEAR / NEUTROPHILS - Has the affinity to neutral dyes, appears color Violet

EOSINOPHILS - Colored red, has the affinity to acidic dyes

BASOPHILS - Has the affinity to basic dyes

AGRANULOCYTES – 35% of total WBC count; do not contain cytoplasmic granules. 2 types: Lymphocytes Monocytes

PLATELETS / THROMBOCYTES - important for blood clotting - 150,000 to 250,000/cubic mm; - very small that they may clamp together.