FaceBase – a tool for community engagement to better understand, treat and prevent craniofacial disorders Nov 16, 2009 Jeff Murray

FaceBase Hub Overview Marazita/Murray Multi Pis Murray General Admin (Budgets, Travel, Meetings, Conference Calls) Advisory Committee Subprojects on UCSC Browser connections (Bob Kuhn) Gene Wiki (Andrew Su) Biorepository (Kate Durda, Dee Even)

Administration Nancy Davin – General Administration Dan Benton – Budgets Susie McConnell – Secretarial Advisory Committee Jill Helms, Michael Cunningham, Mike Dixon, Allen Scott, David Fitzpatrick

Biorepository Kate Durda – Genetic Counselor Consenting and re-consenting, intake, database management, case recruitment Dee Even – Research Technician Sample intake and processing

Human Sample Considerations Cost and Use Blood and its many components Plasma, cells, RNA Tissues (palate etc) Saliva etc (microbiome) Processing and storage Proteome, metabolome, epigenome etc Consent and distribution

Acknowledgments NIDCR Mary Marazita Nancy Davin, Dan Benton, Susie McConnell Kids and their families with clefts Ann Marie and Ryan, Chris, Katie