2003-2004 Immunopharmacology 8 March 2016 7:42 AM.

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Presentation transcript:

Immunopharmacology 8 March :42 AM

Alemtuzumab Antineoplastic Anti-CD52 antibody

Aminoglutethimide Antineoplastic Immunosuppressive Glucocorticoid antagonist Aromatase inhibitor (decreases steroid synthesis)

Anti-thymocyte globulin Immunosuppressive Anti-T cell antibody

Azathioprine Immunosuppressive Antineoplastic Antimetabolite (“pseudofeedback inhibition” of HGPRT and PRP)

Basiliximab Immunosuppressive Anti-CD25 (interleukin 2 receptor) Organ transplant (antirejection)

Cyclosporine Immunosuppressive Antineoplastic Binds cyclophilin Inhibits calcineurin

Daclizumab Immunosuppressive Anti-CD25 (interleukin 2 receptor) antibody Organ transplant (anti-rejection)

Dexamethasone Adrenocorticosteroid Glucocorticoid Antineoplastic Anti-inflammatory steroid Not by inhalation

Ibritumomab Antineoplastic Anti-CD20 antibody

Interferon alpha Antiviral for hepatitis Antineoplastic Cytokine Anti-angiogenesis

Interleukin 2 Cytokine Antineoplastic

Interleukin 11 Cytokine Antineoplastic (supporting agent)

Methotrexate Immunosuppressive Antineoplastic Folic acid antagonist Dihydrofolate reductase inhibitor

Muromonab-CD3 Immunosuppressive Mouse monoclonal anti-CD3 antibody Organ transplant (anti-rejection)

Mycophenolate Immunosuppressive Inhibits inosine monophosphate dehydrogenase activity

Palivizumab Antiviral Monoclonal antibody against the surface of respiratory syncytial virus

Rituxumab Antineoplastic Anti-CD20 antibody

Sirolimus Immunosuppressive Binds FKBP, inhibits mTOR (mammalian kinase target of rapamycin) & cell cycle progression Rapamycin

Tacrolimus Immunosuppressive Antineoplastic Binds FKBP (FK506 binding protein) Inhibits calcineurin

Trastuzumab Antineoplastic Anti-HER2 antibody

Tumor necrosis factor  Cytokine Antineoplastic