Thrombus Obliteration by Rapid Percutaneous Endovenous Intervention in Deep Venous Occlusion “TORPEDO” trial : Mid –Term results Mohsen Sharifi,MD,FACC, Mahshid Mehdipour, Curt Bay, PhD, Gary Smith,MD, Jalaladdin Sharifi,MD Arizona Cardiovascular Consultants & A.T. Still University, Mesa, AZ

TORPEDO TRIAL First Randomized trial Evaluating Reduction of DVT Sequelae with Percutaneous Endovenous Intervention (PEVI)

183 Randomized Control No=92 PEVI No=91 8 pts PEVI 88 Control 81 F/U at 30±5months

TORPEDO TRIAL Primary endpoints Post- thrombotic Syndrome Recurrent Venous Thromboembolic Disease Secondary Endpoints Skin Induration Leg Edema Hospital Stay Subjective Perception of Improvement Bleeding

Conclusions PEVI + anticoagulation is superior to anticoagulation alone in: Reduction of recurrent VTE. Reduction of PTS Reduction of hospital stay Reduction of leg edema Reduction of skin induration Reduction in duration of parenteral anticoagulants Subjective perception of improvement