Reaxys Demonstration Search Chemistry 137 – Spring 2013 Grace Baysinger Head Librarian & Bibliographer, Swain Chemistry & Chemical Engineering Library

Reaxys – Home Page There are three tabs for searching. Chose Substances and Properties.

Reaxys – Generate Structure from Name Click on Generate structure from name button. Then enter name in popup box.

Reaxys – Found Chemical Structures If more than one structure is retrieved, choose one that best matches your needs.

Reaxys – Substructure Search of Vancomycin Do substructure search, include tautomers and ignore stereo

Reaxys – Initial Search Results Summary of available information for each structure Filters for refining search results

Reaxys – Filter by Bioactivity – Limit to Substances with Pharmacological Data

There are 3,747 articles/patents that have bioactivity on Vancomycin

Reaxys – Limit to Articles/Patents Published in

Reaxys – Citations Display Form for Reviewing Results View results in Citations format to see titles of articles of potential interest

Reaxys – Output Results Click on Output choice to create PDF of search results

Reaxys – Popup Window Choices for Specifying Output Format

Reaxys – Output Citation Results

Reaxys – Record from Output that includes Hit Substance, Citation, and Abstract for Reference with Bioactivity Information View in Reaxys hot link lets you go to substance record for that compound from PDF

Reaxys – Online Training at Training center includes Quick Reference Guide