Warm-up 12/9/15: Complete the EOC Practice on Transcription that you picked up when you entered.  You may write on this sheet  Choose the best answer.

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Warm-up 12/9/15: Complete the EOC Practice on Transcription that you picked up when you entered.  You may write on this sheet  Choose the best answer  Provide an explanation to justify why you selected the answer that you did.  Use your notes to help you answer the questions.

At your station you will find three DNA sequences, transcribe the complementary RNA sequences on your warm-up sheet for this week.  Label this practice “Transcription Station 1”

Today we will…  Warm-up: Transcription Practice EOC Questions  Transcription Station 1  What Does Translation Mean to You?  Protein Synthesis Guided Notes  Necklace Factory Analogy  Cookie Factory Analogy Gallery Walk  Autoville Practice  Protein Synthesis Annotation and Checkpoint Questions  Translation Practice Problems

So…  Now we know the DNA codes for the proteins that need to be made..  And, that mRNA picks that code up and brings it to the ribosome.  But…then what?

Lost in Translation  What does translation mean?  When have you had to translate something?

What is TRANSLATION?  The GOAL of TRANSLATION is to link amino acids together to make PROTEINS RNA  PROTEIN

Proteins

Function 1.Build and repair body tissue 2.Fight diseases (antibodies) 3.Send messages (hormones) 4.Control reactions (enzymes) 5.Maintain homeostasis = regulate the body Subunits Amino Acids Pictures

Where does TRANSLATION take place?  The CYTOPLASM and RIBOSOMES  CYTOPLASM: because the mRNA travels our of the nucleus into the cytoplasm on the way to the Ribosome  RIBOSOME: because this is where the proteins are actually made

What are the STEPS of Translation? 1. mRNA attaches to the ribosome 1. Ribosome “reads” the mRNA groups in THREE BASES = a CODON 1. a. Each CODON codes for a certain amino acid 2. A tRNA molecule comes along with the right ANTICODON to match the CODON 1. CODON = AAA ANTICODON = 2. CODON = UAG ANTICODON = 3. The tRNA molecules “carries” the amino acids and links them together with PEPTIDE bonds to make a PROTEIN

What is another name for PROTEINS?  POLYPEPTIDES because they are made of many PEPTIDE BONDS

IMPORTANT TERMS: CODON = is a set of THREE NITROGEN BASES ONE CODON = ONE AMINO ACID TRANSCRIPTION = DNA  mRNA (in nucleus) TRANSLATION = RNA  PROTEIN (in cytoplasm/ribosome)

But…  What does this actually look like?