CHAPTER 5 Renal Allograft Biopsy Wong Hin Seng 5 th MRRB report 2011 & 2012, Malaysia

Table 5.2.1: Number of renal allograft biopsy, Year Total Number of renal transplant biopsy th MRRB report 2011 & 2012, Malaysia

Figure 5.2.1: Number of renal allograft biopsy, th MRRB report 2011 & 2012, Malaysia

Table 5.2.2: Number of renal allograft biopsy by centre, Centre IDCentre Total n%n%n%n%n%n%n%n%n% Kuala Lumpur Selayang (Adult) UMMC Prince Court Medical Centre Kuala Lumpur (Paed) Tengku Ampuan Rahimah Penang (Adult) Sarawak General Sultanah Bahiyah PPUKM Sultan Ismail (Paed) Sultanah Aminah Melaka Tuanku Ja'afar Hospital Raja Permaisuri Bainun Serdang Queen Elizabeth Sultanah Fatimah Penang (Paed) Selayang (Paed) Normah Medical Specialist Centre Fan Medical Renal Clinic KPJ Ampang Puteri Specialist Tengku Ampuan Afzan Sultanah Nur Zahirah Raja Perempuan Zainab II Loh Guan Lye Specialist Centre Total UMMC: University Malaya Medical Centre. PPUKM: Pusat Perubatan Universiti Kebangsaan Malaysia 5 th MRRB report 2011 & 2012, Malaysia

Table 5.2.3: Renal allograft biopsy by year and age group, rate per million populations, Age group Total n%Raten% n% n% n% n% n% n% n% < < < < < < > Total th MRRB report 2011 & 2012, Malaysia

Figure 5.2.3: Renal allograft biopsy by year and age group, rate per million populations, th MRRB report 2011 & 2012, Malaysia

Table 5.3.1: Indications for renal allograft biopsy, Current clinical presentation n%n%n%n%n%n%n%n% Urine abnormality Nephrotic syndrome Gross hematuria Acute deterioration of graft function Creeping creatinine Non/Poor delayed graft function Missing/Not available Total th MRRB report 2011 & 2012, Malaysia

Figure 5.3.1: Indications for renal allograft biopsy, th MRRB report 2011 & 2012, Malaysia

Table 5.4: Timing of renal allograft biopsy, (dates: date of biopsy & date of transplant) Timing of renal transplant biopsy Within 1 week >1 week to 1 month > 1month to 3 months > 3 months to 6 months > 6months to 1 year >1 yr post transplant Total n%n%n%n%n%n%n% Total th MRRB report 2011 & 2012, Malaysia

Figure 5.4: Timing of renal allograft biopsy, th MRRB report 2011 & 2012, Malaysia

Table 5.5.1: Biopsy method, Method Total n%n%n%n%n%n%n%n%n% Blind (not US guided) US guided: real-time US guided: not real- time Missing* Total *No data on biopsy technique 5 th MRRB report 2011 & 2012, Malaysia

Figure 5.5.1: Biopsy method (censored for missing data), th MRRB report 2011 & 2012, Malaysia

Table 5.5.2: Number of passes, Number of passes Total n%n%n%n%n%n%n%n%n% Missing/ Not available Total * No data information on number of passes 5 th MRRB report 2011 & 2012, Malaysia

Figure 5.5.2: Number of passes, th MRRB report 2011 & 2012, Malaysia

Table 5.5.3: Number of glomeruli obtained on biopsy, Number of glomeruli obtained Total n%n%n%n%n%n%n%n%n% > Missing/ Unknown* Total * No data information on the number of glomeruli 5 th MRRB report 2011 & 2012, Malaysia

Figure 5.5.3: Number of glomeruli obtained on biopsy, th MRRB report 2011 & 2012, Malaysia

Table 5.5.4: Type of complications, Type of complications Total n%n%n%n%n%n%n%N%n% No complication Mild complication a Severe complication b Missing / Unknown c Total a Mild complication is defined as presence of gross hematuria, perirenal collection, hematoma, or AVM that do not require intervention b Severe complication is defined as presence of hypotension or complications requiring intervention. c No data information for complications 5 th MRRB report 2011 & 2012, Malaysia

Table 5.6: Histological diagnosis, Histological Diagnosis Total n%n%n%n%n%n%n%n%n% Acute rejection Borderline rejection Calcineurin inhibitor toxicity Chronic allograft nephropathy Acute tubular necrosis PTLD** De novo Recurrent GN Diabetic nephropathy Others Total Patients may have more than 1 diagnosis classification **Post Transplant Lymphoproliferative disease 5 th MRRB report 2011 & 2012, Malaysia

Figure 5.6: Histological diagnosis, th MRRB report 2011 & 2012, Malaysia