Response to Comment on “Modafinil Shifts Human Locus Coeruleus to Low-Tonic, High-Phasic Activity During Functional MRI” by Michael J. Minzenberg, Andrew.

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Response to Comment on “Modafinil Shifts Human Locus Coeruleus to Low-Tonic, High-Phasic Activity During Functional MRI” by Michael J. Minzenberg, Andrew J. Watrous, Jong H. Yoon, Christian La, Stefan Ursu, and Cameron S. Carter Science Volume 328(5976): April 16, 2010 Published by AAAS

Fig. 1 Axial views of (A) template brain, (B) LC mask from (14), (C) original drug effect masked to LC, (D) original drug effect in unsmoothed data, masked to LC, and (E) results in new sample using high-resolution echo planar imaging. Michael J. Minzenberg et al. Science 2010;328:309 Published by AAAS

Fig. 2 Three-plane views of results summarized in Fig. 1. Michael J. Minzenberg et al. Science 2010;328:309 Published by AAAS