2. PANCREAS DR.DEEPAK N.KHEDEKAR. MBBS; MD. DEPT.OF ANATOMY LTMMC & GH,SION,MUMBAI 2014

3. Pancreas –all flesh

4. Introduction… Soft, lobulated elongated gland with both exocrine and endocrine functions Exocrine –pancreatic juice Endocrine-insulin

5. Location… epigastric & left hypochondriac regions behind the stomach and lesser sac Transversely across the posterior abdominal wall at the level of the L2 &L3

6. Size and shape… J shaped or retort shaped. Length-15-20 cm Thickness- 1.2-1.8 cm Breadth-2.5 -3.8 cm Wt-90 gm

7. Parts …

8. Head … Enlarged part C shaped, lying within the concavity of duodenum, consist of 3 borders-superior,inferior & right lateral 2 surfaces-anterior & posterior uncinate process

9. Head … Superior border- -1 st part of duodenum -Sup. pancreaticodudenal A. Inferior border- -3 rd part of duodenum -Inf. pancreaticodudenal A. Rt. lateral border- -2 nd part of duodenum -Terminal part of bile duct -Anastomosis betn 2 arteries.

10. Head… Anterior surface 1st part of duodenum. Transverse colon Jejunum separated by peritotneum.

11. Stomach Lesser omentum Lesser sac

13. Head… Posterior surface: IVC Right Renal veins Right crus of diaphragm Bile duct

14. Uncinate process… Triangular projection which arises from lower and left part off the body. Relations: Anterior: -Superior mesenteric vessels. Posterior -Aorta Above -Left renal vein

15. Neck… Relations: Anterior surface Peritoneum covering lesser sac Pylorus

16. Neck … Posterior surface is related to superior mesenteric vein portal vein

17. Body… Elongated part. Extends from neck to the tail. Passes toward the left with slight upward and backward inclination

18. Body… Triangular in cross section 3 borders- -Anterior -superior -Inferior Tuber omentale - small projection on superior border little to the left of the neck

19. Body-Relations… Borders: Anterior attach to root of the tranverse mesocolon. Superior related to coeliac trunk, hepatic artery & splenic artery Inferior is related to superior mesenteric artery.

20. Body-Relations… Surfaces: Anterior is convex covered by the peritoneum related to the lesser sac & stomach. Inferior surface covered by the peritoneum related the DJ flexure coils of jejunum & Lt. colic flexure.

21. PERITONEUMPERITONEUM

22. Posterior relations…

23. Body –relations… Posterior surface -Aorta -Left crus of the diaphragm -Left kidney -Left Suprarenal gland -Left renal vessels -Splenic vein

24. Tail … Left end of the pancreas Lies in the lienorenal ligament,together with the splenic vessels Related to the lower part of the spleen (gastric surface.

25. Ducts system… Exocrine part of pancreas is drained by the 2 ducts Main Accessory.

26. Main pancreatic duct of wirsung… Lies near posterior surface,3 mm in diam.white in colour Begins at the tail, runs throughout the body,bends at the neck to run downwards backwards in the head. Herring bone pattern

27. Herring bone pattern…

28. Main pancreatic duct of wirsung… Lies near the posterior surface of the pancreas White in color Begins at the tail, runs to the right through the body, bends at the neck runs downwards backwards and to the right in the head.

29. Main pancreatic duct of wirsung… In the head of the pancreas, it is related to the bile duct(on rt. side) Two ducts open in the wall of the 2 nd part of the duodenum and join to form hepatopancreatic ampulla of vater which open as major duodenal papilla,8-10 cm distal to pylorus.

30. Accessory duct of Santorini… Begins in the lower part of head, crosses the main duct with which it communicates Opens as minor duodenal papilla in the 2 nd part of duodenum (6-8 cm distal to pylorus)

31. Arterial supply… -Splenic A. -Superior pancreatico- duodenal artery (from coeliac trunk) -Inferior pancreatico- duodenal A.(from superior mesenteric A)

32. Venous drainage… -Splenic vein -Superior mesenteric vein -Portal vein

33. Nerve supply… Parasympathetic by the vagus nerve controlling secretion. Sympathetic from coeliac & superior mesenteric plx. Secretion is also controlled by harmone secretin- pancreozymine.

34. Lymphatic drainage… Head & neck – ventral & dorsal pancreaticodudenal grp LN. Body &tail by pancreatico-splenic LN. Efferents to Coeliac & sup.mesenteric LN

35. Applied anatomy… Congenital Truama Infection /inflammation Tumour Procedures

36. Congenital… Annular pancreas: Developmental anomaly where ring of pancreatic tissue surrounds and obstruct duodenum

37. Truama… Results from sudden forceful compression of abdomen such as steering wheel leading to rupture. Digestion of pancreas and surrounding tissue by free pancreatic juice is very painful clinical condition.

38. Inflammation… Pancreatitis May be primary or secondary due to gall stone. Results in collection of fluid in the lesser sac Pain is poorly localised,referred to epigastrium. Acute pancreatitis is serious clinical condition may be due to mumps

39. Acute pancreatitis

40. Carcinoma… Common in head Causes obstructive jaundice due to BD compression Causes ascites due to portal vein compression. Causes pyloric obstruction.

41. Procedures… Endoscopic retrograde cholangiopancreatico graphy-Std procedure for Dx of pancreatic & biliary diseases

42. Diabetes mallitus… condition in which the pancreas no longer produces enough insulin or cells stop responding to the insulin that is produced, so that glucose in the blood cannot be absorbed into the cells of the body. Symptoms :frequent urination, lethargy, excessive thirst, and hunger. Rx- includes changes in diet, oral medications, and in some cases, daily injections of insulin.

43. DEPT. OF ANATOMY,LTMMC &GH SION MUMBAI 2014