1. Exploration of Microscopic Structures Johannes Evangelista Purkinje (1787-1869) Jules Gabriel Francois Baillarger (1809-1890) Theodor Schwann (1810-1882) Robert Remak (1815-1865) Theodor Meynert (1833-1892) Otto Friedrich Karl Deiters (1834-1863) Vladimir Alexandrovitch Betz (1834-1894) Louis Antoin Ranvier (1835-1922) Johannes Evangelista Purkinje (1787-1869) Jules Gabriel Francois Baillarger (1809-1890) Theodor Schwann (1810-1882) Robert Remak (1815-1865) Theodor Meynert (1833-1892) Otto Friedrich Karl Deiters (1834-1863) Vladimir Alexandrovitch Betz (1834-1894) Louis Antoin Ranvier (1835-1922) History of Neuroanatomy

2. 19th Century Neuroanatomy Johannes Evangelista Purkinje (1787-1869) Johannes Evangelista Purkinje (1787-1869) Cerebellar Purkinje cell Cardiac Purkinje fiber

3. 19th Century Neuroanatomy Cerebellar Purkinje cell peripheral nerve

4. 19th Century Neuroanatomy Jules Gabriel Francois Baillarger (1809-1890) Jules Gabriel Francois Baillarger (1809-1890) Inner and outer band of Baillarger in cerebral cortex Inner and outer band of Baillarger in cerebral cortex

5. 19th Century Neuroanatomy Inner and outer band of Baillarger (1840) - demonstrate laminar nature of cerbral cortex Inner and outer band of Baillarger (1840) - demonstrate laminar nature of cerbral cortex cf. Francesco Gennari (1750-1797), Italian medical student cf. Francesco Gennari (1750-1797), Italian medical student

6. 19th Century Neuroanatomy Theodor Schwann (1810-1882) Schwann cell cell theory Theodor Schwann (1810-1882) Schwann cell cell theory

7. 19th Century Neuroanatomy Robert Remak (1815-1865) Robert Remak (1815-1865) unmyelinated fiber (fiber of Remak) unmyelinated fiber (fiber of Remak)

8. 19th Century Neuroanatomy Theodor Meynert (1833-1892) Theodor Meynert (1833-1892) basal nucleus of Meynert dorsal tegmental decussation of Meynert basal nucleus of Meynert dorsal tegmental decussation of Meynert

9. 19th Century Neuroanatomy Otto Friedrich Karl Deiters (1834-1863) Deiter’s nucleus (lateral vestibular nucleus) Deiter’s nucleus (lateral vestibular nucleus) illustrate axon and dendrite from neuroal cell body illustrate axon and dendrite from neuroal cell body

10. 19th Century Neuroanatomy Vladimir Alexandrovitch Betz (1834-1894) giant pyramidal cell of Betz giant pyramidal cell of Betz

11. 19th Century Neuroanatomy Louis Antoin Ranvier (1835-1922) node of Ranvier Neuro- histology Textbook node of Ranvier Neuro- histology Textbook

12. Development of Staining Methods Joseph von Gerlach (1820-1896) Camilio Golgi (1843-1926) Carl Weigert (1845-1904) Santiago Ramon y Cajal (1852-1934) Franz Nissl (1860-1919) Max Bielschowsky (1869-1940) Pio del Rio Hortega (1882-1945) Joseph von Gerlach (1820-1896) Camilio Golgi (1843-1926) Carl Weigert (1845-1904) Santiago Ramon y Cajal (1852-1934) Franz Nissl (1860-1919) Max Bielschowsky (1869-1940) Pio del Rio Hortega (1882-1945) History of Neuroanatomy

13. Development of Staining methods Joseph von Gerlach (1820-1896) founder of staining technique use carmine to stain tissue (cerebellum) in 1858 Joseph von Gerlach (1820-1896) founder of staining technique use carmine to stain tissue (cerebellum) in 1858

14. Development of Staining methods Weigert (1845-1904) Weigert (1845-1904) Nissl (1860-1919) Nissl (1860-1919) Bielschowsky (1869-1940) Bielschowsky (1869-1940) del Rio-Hortega (1882-1945) del Rio-Hortega (1882-1945)

15. Development of Experimental Neuroanatomical Techniques Development of Experimental Neuroanatomical Techniques Augustus Volney Waller (1816-1870) Bernhard Aloys von Gudden (1824-1886) Wilhelm His (1831-1904) Paul Emil Fleschig (1847-1929) Vittorio Marchi (1851-1908) Augustus Volney Waller (1816-1870) Bernhard Aloys von Gudden (1824-1886) Wilhelm His (1831-1904) Paul Emil Fleschig (1847-1929) Vittorio Marchi (1851-1908) History of Neuroanatomy

16. 19th Century Neuroanatomy Augustus Volney Waller (1816-1870) Augustus Volney Waller (1816-1870) Wallerian degeneration

17. 19th Century Neuroanatomy Bernhard Aloys von Gudden (1824-1886) Bernhard Aloys von Gudden (1824-1886) dorsal tegmental nucleus of Gudden method of Gudden Ludwig II of Barvaria, von Gudden’s patient

18. 19th Century Neuroanatomy Wilhelm His (1831-1904) Histogenesis of the nervous system Wilhelm His (1831-1904) Histogenesis of the nervous system

19. 19th Century Neuroanatomy Paul Emil Fleschig (1847-1929) myelogenetic study of the nervous system Paul Emil Fleschig (1847-1929) myelogenetic study of the nervous system

20. 19th Century Neuroanatomy Vittorio Marchi (1851-1908) March V, Algeri G (1885) Sulle degenerazioni discendenti consecutive a lesioni della cortessia cerbrale. Riv Sper Freniat 11:492-494. March V, Algeri G (1885) Sulle degenerazioni discendenti consecutive a lesioni della cortessia cerbrale. Riv Sper Freniat 11:492-494.