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Skin-Derived Fibroblasts for the Treatment of Refractory Achilles Tendinosis: Preliminary Short-Term Results by Haron Obaid, Andrew Clarke, Peter Rosenfeld, Christopher Leach, and David Connell J Bone Joint Surg Am Volume 94(3):193-200 February 1, 2012 ©2012 by The Journal of Bone and Joint Surgery, Inc.
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Flow diagram for the patients with unilateral involvement, demonstrating the enrollment, allocation, follow-up, and analysis stages of the trial. Haron Obaid et al. J Bone Joint Surg Am 2012;94:193-200 ©2012 by The Journal of Bone and Joint Surgery, Inc.
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Flow diagram for the patients with bilateral involvement, demonstrating the enrollment, allocation, follow-up, and analysis stages of the trial. Haron Obaid et al. J Bone Joint Surg Am 2012;94:193-200 ©2012 by The Journal of Bone and Joint Surgery, Inc.
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Skin-derived fibroblasts on day 0 (Fig. 3-A) and eleven days after culture (Fig. 3-B) (magnification, ×200). Haron Obaid et al. J Bone Joint Surg Am 2012;94:193-200 ©2012 by The Journal of Bone and Joint Surgery, Inc.
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The preliminary ultrasound shows severe tendinosis manifested by marked fusiform thickening, hypoechoic changes, and longitudinal intrasubstance tears. Haron Obaid et al. J Bone Joint Surg Am 2012;94:193-200 ©2012 by The Journal of Bone and Joint Surgery, Inc.
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An ultrasound examination performed six months after cell therapy, showing a reduction in tendon thickness, increased echotexture, and resolution of the intrasubstance tears. Haron Obaid et al. J Bone Joint Surg Am 2012;94:193-200 ©2012 by The Journal of Bone and Joint Surgery, Inc.
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The VISA scores (y axis) before and after treatment for the cell therapy group and the control group (intergroup) and between baseline and six months after treatment (within-group). Haron Obaid et al. J Bone Joint Surg Am 2012;94:193-200 ©2012 by The Journal of Bone and Joint Surgery, Inc.
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The VAS scores (y axis) before and after treatment for the cell therapy and control groups (intergroup comparison) and between baseline and six months after treatment (within-group). Haron Obaid et al. J Bone Joint Surg Am 2012;94:193-200 ©2012 by The Journal of Bone and Joint Surgery, Inc.
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