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A Cross-Sectional Study on the Effect of Smoking on the Semen Analysis of 21 year old males and older in Barangay Cembo, Makati City from May – June 2009 Baraan, Amadeus Capco, Diorella Anne Manotok, Ma. Veronica Mata, Cecille Moderes, Vincent Nova, Isabelle Ortiz Luis, Guinevere Osias, Jerny Pabalan, Jorja Palis, Alexandra Jean Pallera, Julius Peñaflorida, Andrea
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Community dimensions SECONDARILY RELATED TO HEALTH
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Barangay Profile Previously a housing area for enlisted members at Fort William McKinley Population = 28,815 Physical structures – Homes – Government offices – Schools – Trading establishments
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Barangay Profile Transport and communication – Tricycles, taxi, jeepneys, Fx taxi – Landline, mobile phones Leadership – One barangay captain – Seven barangay councilors – Sangguniang Kabataan
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Community dimensions DIRECTLY RELATED TO HEALTH
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Age Distribution (2007 Data) Total population (2007) = 21,623 – Males = 10,419 – Females = 11,214 – 5-9 years old = 3092 – 1-4 years old = 2855 – 10-14 years old = 2660
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Table 2. MAKATI HEALTH DEPARTMENT VITAL HEALTH STATISTICS Total live births Male246 Female270 516 Distribution of maternal deliveries Home71 lying-in155 govt hosp143 Private hosp147
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Ten Leading causes of morbidity on all ages in Barangay Cembo, Makati (2008)
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Background Males produce semen in the process of intercourse – from the male gonad, Contains spermatozoa – alkaline mucus helps neutralize acidity Smoking is known to produce adverse effects to the body – Degenerative disease – Nicotine deterrent to spermatozoa
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prevalence of smoking adult males at 46% between 20 and 39 years (Langgassner, 1999) Studies performed in the last 5 years reveal a decrease in sperm quality in relation to smoking – Males of the reproductive age – Sperm analysis done
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Objectives General: This study aims to investigate the effect of cigarette smoking on the semen analysis of males, particularly on the parameters of semen volume, sperm motility, sperm morphology, and sperm count.
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Specific: Provide baseline information on the effect of cigarette smoking and sperm characteristics of males residing at Cembo, Makati Describe the participants of the study as to the socio-demographic characteristics; and
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Determine the association between cigarette smoking of males to the following parameters: – semen volume – sperm motility – sperm morphology – sperm count
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Scope and Limitations legal age for to avoid sensitive issues regarding the sexual aspect of our study Barangay Cembo, Makati City To exclude residents with existing comorbidities sperm analysis – individual influence on each parameter may be described may contribute to baseline knowledge
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Methodology Inclusion criteria – Males aged 21 and older – Residents of Cembo Sample Collection – Participants advised for a three day abstinence Data Analysis – Odds ratio, sample size determination Sample Size n is the required sample size t is the confidence level at 95% (standard value of 1.96) p is the estimated prevalence of smoking m is the margin of error at 5% (standard value of 0.05) n=n=t² x p(1-p) m²
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RESULTS
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Sociodemographic Characteristics Smoker GroupNon-smoker Group (N = 24)(N = 6) Charateristic Age – yr 22-5728-48 Married - no./total no. 19/24 (79.2%)4/6 (66.7%) Comorbidities - no/total no. 11/24 (45.8%/)1/6 (16.7%) Personal & Social History Alcoholic beverage drinker 19/24 (79.2%)2/6 (33.3%) Illicit drug use 3/24 (12.5%)1/6 (16.7%)
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Semen Volume
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Sperm Motility
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Sperm Morphology
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Sperm Count
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Majority of results were normal – Sample size was less than expected Abnormal results were detected among the population – Smokers – No existing disease Odds ratio – semen volume (0.4) – sperm motility (0.71) – sperm morphology (0.45) – sperm count (0.2272)
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Discussion smoking decreases the quality of semen parameters – Chia et al (1998), Hellstrom et al (2006), Eskenazi et al (2003), Sofikitis et al (1995), Zinaman et al (2000), Sloter et al (2006), Mehrannia, T. (2007) This study’s result = – More participants with normal semen parameters – Abnormal parameters identified
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Summary Cigarette smoking is a public health concern Male reproductive health also a focus for concern Male constituents of a population was studied – Reproductive age – Varied socio-demographic characteristics No clear trend seen from the data Abnormal semen parameters seen
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Recommendations Another study to verify data is suggested – Improve sample size – To see association with pack-years and effects on semen analysis – Standardize manner of semen collection Address the subjects regarding sensitivity of issue – Administer public health lectures – Encouragement by the local government units
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Thank you
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