1. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings PowerPoint ® Lecture Slide Presentation prepared by Christine L. Case Microbiology B.E Pruitt & Jane J. Stein AN INTRODUCTION EIGHTH EDITION TORTORA FUNKE CASE Chapter 24, part B Microbial Diseases of the Respiratory System

2. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Tuberculosis Figure 24.9 Mycobacterium tuberculosis: Acid-fast rod. Transmitted from human to human M. bovis: <1% U.S. cases, not transmitted from human to human M. avium-intracellulare complex infects people with late stage HIV infection

3. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Tuberculosis Figure 24.10.1

4. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Tuberculosis Figure 24.10.2

5. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Tuberculosis Figure 24.10.3

6. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Treatment of Tuberculosis: Prolonged treatment with multiple antibiotics Vaccines: BCG, live, avirulent M. bovis. Not widely used in U.S. Tuberculosis

7. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Tuberculosis Figure 24.11 Diagnosis: Tuberculin skin test screening + = current or previous infection Followed by X-ray or CT, acid-fast staining of sputum, culturing bacteria

8. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Tuberculosis Figure 14.11c

9. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Tuberculosis Figure 24.12

10. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Pneumomoccal Pneumonia Figure 24.13 Streptococcus pneumoniae: Gram-positive encapsulated diplococci Diagnosis by culturing bacteria Penicillin is drug of choice

11. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Pneumomoccal Pneumonia

12. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Gram-negative coccobacillus Alcoholism, poor nutrition, cancer, or diabetes are predisposing factors Second-generation cephalosporins Haemophilus influenzae Pneumonia