1. The Cancer Burden in Iowa: Data Overview

2. Treatment BirthDeathCancer Diagnosis Genes Environment Etiology & Prevention Early Detection Quantity & Quality of Life Positive InfluencesProtective Factors Population Interests in Cancer Prevention and Control Risk FactorsNegative Influences Incidence RatesSurvival RatesStage Distribution Mortality Rates

3. Measured Progress toward Cancer Mortality Goals in Healthy Iowans 2010* 1994-96 2003-05 Percent 2010 GoalCancer SiteGenderBaseline Rate* Rate* Improvement + Rate Goal* $ 2-1All sites M & F 196.4 182.8 6.9% 173.0 2-4Lung M & F 54.1 53.1 1.8% 46.0 2-9ProstateM 36.0 26.0 27.8% 26.0 2-5Breast F 29.0 22.1 23.8% 19.0 2-7ColorectumM & F 23.2 18.7 19.4% 15.5 2-8Oral Cavity & PharynxM & F 2.6 2.5 3.8% 1.8 2-6Cervix F 2.6 2.2 15.4% 1.9 2-10Skin MelanomaM & F 2.5 2.4 4.0% 1.9 * Expressed per 100,000 and age-adjusted to Year 2000 U.S. standard + Determined by subtracting the 2003-05 rate from the 1994-96 rate and dividing by the 1994-96 rate. $ Healthy Iowans 2010 midcourse revision goal

4. Prostate Cancer Mortality Rates in Iowa, 1994-2005 27.8% reduction Year Rate per 100,000

5. Female Breast Cancer Mortality Rates in Iowa, 1994-2005 23.8% reduction Year Rate per 100,000

6. Colorectal Cancer Mortality Rates in Iowa, 1994-2005 19.4% reduction Year Rate per 100,000

7. Lung Cancer Mortality Rates in Iowa by Sex, 1994-2005 10.5% reduction Year Rate per 100,000 9.5% increase

8. Estimated Lives Saved from Cancer Death, Iowa, 1997-2005 Total lives saved = 3,066 * Computed using indirect standardization with sex- and age-specific rates for 1994-1996 as the standard

9. Distribution of 3,066 Estimated Lives Saved by Cancer Site and Gender, Iowa, 1997-2005 Estimated Lives Saved* Cancer SiteMalesFemalesTotal All sites 2,103 9633,066 Prostate 840 - 840 Colorectum 302 492 794 Breast - 708 708 Lung 982 -323 659 Oral Cavity & Pharynx 33 48 81 Cervix - 47 47 Skin Melanoma 11 8 19 All Other Sites -65 -17 -82 * Computed using indirect standardization with age-specific rates for 1994-96 as the standard

10. Distribution of 963 Estimated Lives Saved by Characteristic, Female, Iowa, 1997-2005 Characteristic Number of Deaths SMR ObservedExpected Age 0-19 20-44 45-64 65-74 75+ 87 916 5,818 6,495 14,333 107 1,052 6,546 6,734 14,173 0.81* 0.87* 0.89* 0.96* 1.01 Race White Black Other 27,174 351 124 28,161 285 166 0.96* 1.23* 0.75* Urban/Rural MSA >20,000 10-20,000 Rural 13,029 6,623 6,079 1,918 13,247 6,852 6,491 2,022 0.98 0.97* 0.94* 0.95* * P-value < 0.05

11. Distribution of 2,103 Estimated Lives Saved by Characteristic, Males, Iowa, 1997-2005 Characteristic Number of Deaths SMR ObservedExpected Age 0-19 20-44 45-64 65-74 75+ 128 783 6,526 8,329 14,115 97 923 7,278 8,635 15,051 1.32* 0.85* 0.90* 0.96* 0.94* Race White Black Other 29,305 451 125 31,488 320 176 0.93* 1.41* 0.71* Urban/Rural MSA >20,000 10-20,000 Rural 13,709 7,532 6,517 2,123 14,540 7,712 7,428 2,304 0.94* 0.98* 0.88* 0.92* * P-value < 0.05

12. New Tool  Iowa Cancer Incidence and Mortality Data  Available on State Health Registry of Iowa website http://www.public-health.uiowa.edu/shri/Index.html under “Iowa Cancer Data” subheading