1. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Virus Families 1.Single-stranded DNA, nonenveloped viruses, polyhedral capsid Size: 18-25 nm Parvoviridae Human parvovirus gastroenterities

2. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 2. Double-stranded DNA, nonenveloped viruses Polyhedral capsid Size: 70-90 nm Adenoviruses Respiratory infections in humans Tumors in animals

3. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 2`.Double-stranded DNA, nonenveloped viruses Polyhedral capsid Size: 40-57 nm Papillomavirus (human wart virus) Polyomavirus Cause tumors, some cause cancer

4. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 3. Double-stranded DNA, enveloped viruses Size: 200-350 nm Orthopoxvirus (vaccinia and smallpox viruses) Molluscipoxvirus Smallpox, molluscum contagiosum, cowpox

5. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Polyhedral capsid Size: 150-200 nm Simplexvirus (HHV1 and HHV 2) Varicellavirus (HHV 3) Lymphocryptovirus (HHV 4) Cytomegalovirus (HHV 5) Roseolovirus (HHV 6) HHV 7 Kaposi's sarcoma (HHV 8) Some herpesviruses can remain latent in host cells 4. Double-stranded DNA, enveloped viruses

6. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 4`.Double-stranded DNA, enveloped viruses Size: 42 nm Hepadnavirus (Hepatitis B virus) Use reverse transcriptase to produce DNA from mRNA

7. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 5. Single-stranded RNA, + strand, nonenveloped Polyhedral capsid Size: 28-30 nm Enterovirus Enteroviruses include poliovirus and coxsackievirus Rhinovirus Hepatitis A virus

8. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 6. (+)Single-stranded RNA, enveloped Usually polyhedral capsid. Size: 60-70 nm Arboviruses Eastern and western equine encephalitis Rubivirus (rubella virus)

9. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 6`. (+)Single-stranded RNA, enveloped Size: 40-50 nm Flaviviruses can replicate in arthropods; include yellow fever, dengue, SLE, and West Nile viruses Hepatitis C virus

10. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 6``.(+)Single-stranded RNA, enveloped Size: 80-160 nm Coronavirus Upper respiratory infections Common cold; SARS

11. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 7.(-)Single-stranded RNA, enveloped Bullet-shaped Size: 70-189 nm Vesiculovirus Lyssavirus (rabies virus) Cause numerous animal diseases

12. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 7`.(-)Single-stranded RNA,enveloped Long and filamentous Size: 80-14000 nm Filovirus Enveloped, helical viruses Ebola and Marburg viruses

13. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 7``.(-)Single-stranded RNA, enveloped Size: 150-300 nm Paramyxovirus Morbillivirus Paramyxovirus causes parainfluenza, mumps and measles disease

14. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Size: 80-200 nm Influenza virus A, B and C) Influenza C virus Envelope spikes can agglutinate RBCs 8. (-)Strand, multiple RNA strands, enveloped

15. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Size: 90-120 nm California encephalitis virus (encephalitis) Hantaviruses (Hantavirus pulmonary syndrom) 8`. (-)Strand, multiple RNA strands, enveloped

16. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Arenavirus Size: 50-300 nm Helical capsids contain RNA- containing granules Lymphocytic choriomeningitis Fever 8``. (-)Strand, multiple RNA strands, enveloped

17. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Bullet-shaped or polyhedral capsid Size: 100-120 nm Lentivirus (HIV) Oncogenic viruses Use reverse transcriptase to produce DNA from viral genome Includes all RNA tumor viruses 9. (+)Single-stranded RNA, produce DNA, enveloped

18. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 10. Ds RNA, nonenveloped Polyhedral capsid Size: 60-80 nm Reovirus (Respiratory Enteric Orphan) Rotavirus Mild respiratory infections and gastroenteritis Colorado tick fever