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IgM ELISA CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY Jan. 1998, p. 7–10 Vol. 5, No. 1 Copyright © 1998, American Society for Microbiology.

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Presentation on theme: "IgM ELISA CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY Jan. 1998, p. 7–10 Vol. 5, No. 1 Copyright © 1998, American Society for Microbiology."— Presentation transcript:

1 IgM ELISA CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY Jan. 1998, p. 7–10 Vol. 5, No. 1 Copyright © 1998, American Society for Microbiology

2 The combined use of IgM and IgG (commercially available as PanBio Dengue Duo ELISA) (sensitivity, 99%; specificity, 96%) was superior to the use of IgM alone (sensitivity, 88%; specificity, 96%) or IgG alone (sensitivity, 85%; specificity, 96%). This ELISA should prove to be useful in the clinical diagnosis of dengue infection.

3 IgM ELISA Dengue Bulletin 2003 Volume 27 Chapter 16 “Serological Diagnosis of Dengue Fever with IgM Detection” Department of Clinical Virology, Christian Medical College, Vellore-632 004, India

4 The NIV MAC-ELISA showed a high sensitivity (96%) as compared to PanBio Rapid (73%) and PanBio IgM ELISA (72%). But the specificity was low (81%) when compared to PanBio Rapid (95%) and PanBio IgM ELISA (97%) using the latent class analysis model.


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