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DNA Replication – Exciting stuff from chapter 10!

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Presentation on theme: "DNA Replication – Exciting stuff from chapter 10!"— Presentation transcript:

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2 DNA Replication – Exciting stuff from chapter 10!

3 Ch 10 DNA Replication, Baby! DNA workshop – interactive basic overview: http://www.pbs.org/wgbh/aso/tryit/dna/shockwave.html Link to replication animation w/ no sound: http://www.johnkyrk.com/DNAreplication.html Link to genetically engineered corn video: http://www.youtube.com/watch?v=n9xpKx03g9M&feature=player_embedded Link to narrated DNA replication http://highered.mcgraw- hill.com/sites/0072437316/student_view0/chapter14/animations.html#http://highered.mcgraw- hill.com/sites/0072437316/student_view0/chapter14/animations.html# Link to DNA replication http://www.wiley.com/college/boyer/0470003790/animations/replication/replication.ht mhttp://www.wiley.com/college/boyer/0470003790/animations/replication/replication.ht m

4 Review Structure The "rungs" are the nitrogenous base pairs a. complementary base pairing Uniform diameter

5 Review DNA function Stores information Mutates

6 Replicates Expressed

7 DNA REPLICATION When and where? How about in bacteria?

8 Bacteria replication of DNA: one origin of replication

9 DNA replication in eukaryotes: Contain hundreds of origins and complexes make replication “________” that eventually fuse

10 not Replication is called______ _________, because one half of the original strand is always saved, or "conserved"

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12 Process of DNA replication: 1. enz. helicase unwinds and breaks H-bonds 2. single-stranded binding proteins stabilize the molecule

13 3. enz. _________ adds a small piece of _____ (called a primer) to origin of replication (DNA nucleotides can only be added to the end of an _________ chain)

14 4. enz. DNA ____________adds new dNTPs to the ____ end - A-T, G-C, 5'  3 direction of growing strand

15 leading strand - one primer needed lagging strand - Okazaki fragments - primer needed for each fragment

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18 5. A dif. DNA polymerase replaces RNA ___________ w/ DNA 6. enz. DNA ________ joins Okasaki fragments together

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21 Ch 10 DNA Replication, Baby! DNA workshop – interactive basic overview: http://www.pbs.org/wgbh/aso/tryit/dna/shockwave.html Link to replication animation w/ no sound: http://www.johnkyrk.com/DNAreplication.html Link to genetically engineered corn video: http://www.youtube.com/watch?v=n9xpKx03g9M&feature=player_embedded Link to narrated DNA replication http://highered.mcgraw- hill.com/sites/0072437316/student_view0/chapter14/animations.html#http://highered.mcgraw- hill.com/sites/0072437316/student_view0/chapter14/animations.html# Link to DNA replication http://www.wiley.com/college/boyer/0470003790/animations/replication/replication.ht mhttp://www.wiley.com/college/boyer/0470003790/animations/replication/replication.ht m

22 Telomeres - repetitive sequences of nucleotides at the ends of DNA shorten w/ each rep. purpose?

23 Enz. ______________extends telomeres in certain cells 1. stem cells 2. cancer cells

24 Excision repair - repair of damage due to chemicals, radiation, X-rays, UV light What is the result of uncorrected errors? Can mistakes that occur to DNA be repaired?

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