1. Warm-up 12/11: Define the term Homologous? What is a Haploid? Diploid? Your somatic cells have 46 Chromosomes and are diploid cells, –How many chromosomes are in your haploid Gametes? What do you call a photograph of all the chromosomes?

2. Cell Cycle and Mitosis

3. Cell Cycle 3 major phases Interphase: time between cell divisions - G phases: growth - S phase: copying of DNA M phase (mitosis): division of the nucleus Cytokinesis: division of the cytoplasm

4. Mitosis (M phase) 2n  4n chromatids  2 (2n) Continuous process starts with interphase Need to separate the doubled chromosomes Four phases prophase  metaphase  anaphase  telophase PMAT

5. Prophase Can see chromosomes Chromatids stay connected by centromeres Nucleolus and nuclear membrane break down Centrosomes and centrioles appear Early mitotic spindle forms

6. Metaphase Two types of fibers (mitotic spindle) kinetechore fibers: attach to centromere of chromosome polar fibers: extend centrosome to centrosome, push cell apart Fibers line up the chromosomes in middle

7. Anaphase Chromatids of each chromosomes are pulled apart by fibers Move towards opposite poles of dividing cells

8. Telophase Chromosomes in opposite ends Spindle fibers break down Nuclear envelope reforms Nucleolus in each cell Cytokinesis

9. MOVIE

10. Homework Chromosome Structure Due Monday Observing Mitosis Due Tuesday PQRST 154-159 Due Wednesday