1. Chapter 3 Death and Survival on Dialysis Wong Hin Seng Ong Loke Meng Source: 20 th MDTR Report 2012, NRR

2. Table 3.1.1: Deaths on dialysis 1993-2012 Source: 20 th MDTR Report 2012, NRR

3. Figure 3.1.1: Death rates on dialysis 1993-2012 Source: 20 th MDTR Report 2012, NRR

4. Table 3.1.2 (a) : Causes of death on HD dialysis 1994-2012 Source: 20 th MDTR Report 2012, NRR

5. Table 3.1.2 (b) : Causes of death on PD dialysis 1993-2012 Source: 20 th MDTR Report 2012, NRR

6. Table 3.2.1(a): HD Patient survival (censored for change of modality) Dialysis Modality Interval (month) HD n% survivalSE 0 50732100 6 44662940 12 39142890 24 30203790 36 23457700 48 18043630 60 13894560 72 10651500 84 8049440 96 6167390 108 4691350 120 3609310 Source: 20 th MDTR Report 2012, NRR

7. Table 3.2.1(b): PD Patient survival (censored for change of modality) Dialysis Modality Interval (month) PD n% survivalSE 0 7072100 6 6041930 12 5010870 24 3406741 36 2314621 48 1525521 60 1040441 72 690371 84 445321 96 288261 108 191231 120 110201 Source: 20 th MDTR Report 2012, NRR

8. Table 3.2.1(c): HD Patient survival (not censored for change of modality) Dialysis Modality Interval (month) HD n% survivalSE 0 50732100 6 45292940 12 40167890 24 31477790 36 24958710 48 19544630 60 15356560 72 12025510 84 9328450 96 7334410 108 5765370 120 4588330 Source: 20 th MDTR Report 2012, NRR

9. Table 3.2.1(d): PD Patient survival (not censored for change of modality) Dialysis Modality Interval (month) PD n% survivalSE 0 7072100 6 6256930 12 5480870 24 4181741 36 3212631 48 2423541 60 1884471 72 1484421 84 1197381 96 969341 108 789311 120 624281 Source: 20 th MDTR Report 2012, NRR

10. Table 3.2.2(a): Unadjusted HD patient survival by year of entry, 1993- 2012 Source: 20 th MDTR Report 2012, NRR

11. Figure 3.2.2(a): Unadjusted HD patient survival by year of entry, 1993- 2012 Source: 20 th MDTR Report 2012, NRR

12. Table 3.2.2(b): Unadjusted PD patient survival by year of entry, 1993- 2012 Source: 20 th MDTR Report 2012, NRR

13. Figure 3.2.2(b): Unadjusted PD patient survival by year of entry, 1993- 2012 Source: 20 th MDTR Report 2012, NRR

14. Table 3.2.3(a): Unadjusted HD patient survival by age, 1993-2012 Source: 20 th MDTR Report 2012, NRR

15. Figure 3.2.3(a): Unadjusted HD patient survival by age, 1993-2012 Source: 20 th MDTR Report 2012, NRR

16. Table 3.2.3(b): Unadjusted PD patient survival by age, 1993-2012 Source: 20 th MDTR Report 2012, NRR

17. Figure 3.2.3(b): Unadjusted PD patient survival by age, 1993-2012 Source: 20 th MDTR Report 2012, NRR

18. Table 3.2.4(a): Unadjusted HD patient survival by diabetes mellitus status, 1993-2012 Diabetes status Interval (month) Non-diabeticDiabetic n% survivalSEn% survivalSE 0 2324610027980100 6 2071595024566940 12 1855191021160870 24 1496684015567740 36 1226478011343630 48 100377308032540 60 81746805649450 72 66396303859380 84 53305802501310 96 42845401623250 108 34175001010200 120 2712460640160 Source: 20 th MDTR Report 2012, NRR

19. Figure 3.2.4(a): Unadjusted HD patient survival by diabetes mellitus status, 1993-2012 Source: 20 th MDTR Report 2012, NRR

20. Table 3.2.4(b): Unadjusted PD patient survival by diabetes mellitus status, 1993-2012 Diabetes status Interval (month) Non-diabeticDiabetic n% survivalSEn% survivalSE 0 41731003747100 6 36539503057900 12 30829102426811 24 22208211473611 36 1626751852441 48 1145671463311 60 829621247211 72 589561128151 84 38949169101 96 2564213671 108 1713721741 120 101342621 Source: 20 th MDTR Report 2012, NRR

21. Figure 3.2.4(b): Unadjusted PD patient survival by diabetes mellitus status, 1993-2012 Source: 20 th MDTR Report 2012, NRR

22. Figure 3.3.1(a): Variation in patient survival at 1-year among HD centres adjusted for age and diabetes mellitus status, 1993-2011 Source: 20 th MDTR Report 2012, NRR *Horizontal line represents the median % survival among HD centres

23. Figure 3.3.1(b): Funnel plot for adjusted age at 1-year among HD centres adjusted for age and diabetes mellitus status, 1993-2011cohor Source: 20 th MDTR Report 2012, NRR *Horizontal line represents the mean % survival among HD centres

24. Figure 3.3.1(c): Variation in patient survival at 5-years among HD centres adjusted for age and diabetes mellitus status, 1993-2007 Source: 20 th MDTR Report 2012, NRR *Horizontal line represents the median % survival among HD centres

25. Figure 3.3.1(d): Funnel plot for patient survival at 5-years among HD centres adjusted age and diabetes mellitus, 1993-2007cohort Source: 20 th MDTR Report 2012, NRR *Horizontal line represents the mean % survival among HD centres

26. Figure 3.3.2(a): Variation in patient survival at 1-year among PD centres adjusted for age and diabetes mellitus, 1993-2011 Source: 20 th MDTR Report 2012, NRR *Horizontal line represents the median% survival among PD centres

27. Figure 3.3.2(b): Funnel plot of 1-year patient survival from the 90th day of dialysis adjusted for age and diabetes mellitus among PD centres, 1993-2011 cohort Source: 20 th MDTR Report 2012, NRR *Horizontal line represents the mean % survival among PD centres

28. Figure 3.3.2(c): Variation in patient survival at 5-years among PD centres adjusted for age and diabetes mellitus, 1993-2007 Source: 20 th MDTR Report 2012, NRR *Horizontal line represents the mean % survival among PD centres

29. Figure 3.3.2(d): Funnel plot of 5-years patient survival from 90 day of dialysis adjusted for age and diabetes mellitus among PD centres, 1993-2007 cohort Source: 20 th MDTR Report 2012, NRR *Horizontal line represents the median% survival among PD centres

30. Table 3.4.1: Adjusted hazard ratio for mortality of dialysis patients (not censored for change of modality (1993-2012) )

31. Figure 3.4.1(a): Adjusted hazard ratio for mortality of dialysis patients uncensored for change of modality by diastolic blood pressure (1993- 2012 cohort) Source: 20 th MDTR Report 2012, NRR.78 1.01 1 1.15 1.73 0.5 1 1.5 2 Hazard ratio <7070-<8080-<90(ref*)90-<100>=100 Diastolic Blood Pressure (mmHg)

32. Figure 3.4.1(b): Adjusted hazard ratio for mortality of dialysis patients uncensored for change of modality by serum phosphate (1993-2012 cohort) Source: 20 th MDTR Report 2012, NRR 1.59 1.88.82.83 0.5 1 1.5 Hazard ratio <0.80.8-1.3(ref*)1.3-1.81.8-2.2>=2.2 Serum Phosphate (mmol/L)

33. Figure 3.4.1(c): Adjusted hazard ratio for mortality of dialysis patients uncensored for change of modality by hemoglobin (1993-2012 cohort) Source: 20 th MDTR Report 2012, NRR.77 1.82 1.11 0.5 1 Hazard ratio <3.53.5-<4.5 (ref*)4.5-<5.5>=5.5 Calcium Phosphate Product (mmol2/L2)

34. Table 3.4.2: Adjusted hazard ratio for mortality of HD patients uncensored for change of modality (1993-2012 cohort)

35. Figure 3.4.2: Adjusted hazard ratio for mortality of HD patients uncensored for change of modality by Prescribed Kt/V (1993-2012 cohort) Source: 20 th MDTR Report 2012, NRR 1.35 1.11 1 1.15.96 0.5 1 1.5 Hazard ratio <11-<1.21.2-<1.4(ref*)1.4-<1.6>=1.6 Prescribed KT/V-HD

36. Table 3.4.3: Adjusted hazard ratio for mortality of PD patients uncensored for change of modality (1993-2012 cohort)

37. Figure 3.4.4(a): Variations in RAMR by HD centre, 2011 Source: 20 th MDTR Report 2012, NRR

38. Figure 3.4.4(b): Funnel plot of RAMR by HD centre, 2011 Source: 20 th MDTR Report 2012, NRR

39. Figure 3.4.5(a): Variations in RAMR by PD centres, 2011 Source: 20 th MDTR Report 2012, NRR

40. Figure 3.4.5(b): Funnel plot for RAMR by PD centres, 2011 Source: 20 th MDTR Report 2012, NRR