1. Pedigrees Biology 30 Genetics Mrs. S. Pipke-Painchaud

2. Pedigrees A pedigree (family tree) allows you to study the pattern of inheritance with regard to a specific phenotype –Dogs, horses, and a number of other animals have pedigrees or family trees. Definition: diagram showing ancestral relationships and transmission of genetic traits over several generations in a family.

3. Sample Pedigree

4. Diagramming Rules - Female - Male - Unknown sex A shaded in shape means that he or she has the trait in question.

5. Recessive Trait Example Use the letter A

6. Autosomal Dominant Pedigree “Each of the four hallmarks of autosomal dominant inheritance are fulfilled. Each affected individual has an affected parent; there is no skipping of generations. Males and females are equally likely to be affected. About 1/2 of the offspring of an affected individual are affected (the recurrence risk is 1/2). Normal siblings (II-3) of affected individuals have all normal offspring.” (Image and quotation from: http://www.uic.edu/classes/bms/bms655/lesson3.html) http://www.uic.edu/classes/bms/bms655/lesson3.html

7. Myopia Is this a dominant or recessive trait? Why? - Assign letters.

8. X-Linked Pedigree Example

9. Resources Genetics and Rare Conditions Website: –http://www.kumc.edu/gec/support/http://www.kumc.edu/gec/support/ BioLessons: –http://www.biolessons.com/lessonplans/geneti cs/sol_questions/default.asphttp://www.biolessons.com/lessonplans/geneti cs/sol_questions/default.asp