1. © Copyright 2002 Frost & Sullivan. All Rights Reserved. U.S. In Silico Simulation of Biological Systems Markets Reducing Risk in Clinical Trials Prompts Acceptance of Simulation Technologies “With the potential to lower the risk and financial burden of clinical trials, technologies that use computers to model and simulate biological systems are revolutionizing the drug discovery field.” Drug Discovery and Biotechnology Analyst Team Frost & Sullivan

2. © Copyright 2002 Frost & Sullivan. All Rights Reserved. Frost & Sullivan provides: Detailed insights into recent developments and trends Drivers, restraints, challenges, and strategic recommendations Analyst insights into ‘hot topics’ and emerging applications in the “in silico” simulation of biological systems markets Market sizing and competitive analysis Market forecasts and opportunity analysis Quarterly assessments End-user analysis within each report Key Features

3. © Copyright 2002 Frost & Sullivan. All Rights Reserved. Coverage: The United States Proven methodology encompassing extensive primary and secondary data and research Focused information and strategies that cover business and technology issues Credible data and analysis highlighting industry dynamics Precise strategies to help you create winning business plans What We Offer

4. © Copyright 2002 Frost & Sullivan. All Rights Reserved. Current Market Participants Find out how you compare to with the competition Assess current and future drivers and restraints Determine and exploit new market-share opportunities New Entrants Analyze challenges associated with the industry Calculate time scales for strategy implementation Position yourself to capitalize on the unmet needs of the market Investment Community Analyze long-term strategies of companies Determine participants that will outperform the competition Assess attractiveness of investing in the market Who Will Benefit?

5. © Copyright 2002 Frost & Sullivan. All Rights Reserved. 3rd Millennium, Inc. Accelrys Acero, Inc. ArQule /Camitro Automated Cell BeyondGenomics, Inc. Blackstone Computing Cellnomica, Inc. Cellular Genomics, Inc. Cerep CuraGen Corp. DECODON GmbH diaDexus Entelos, Inc. ExonHit Therapeutics, Inc. Gene Network Sciences, Inc. Genomatica, Inc. Integrated Genomics, Inc. Kenna Technologies Large Scale Biology Corp. Lion Biosciences Molecular Mining Pharsight Corp. Physiome Sciences, Inc. Rosetta Inpharmatics/Merck & Co., Inc. Sangamo Biosciences Silico Insights Structural Bioinformatics Visualize Life Sciences Group Key Market Participants

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