1. Copyright © 2010 Ryan P. Murphy

2. Class Expectations –You can show respect by… Listening when the teacher or others are talking. –One speaker at a time, please raise your hand. Please no cross-room conversations during work time…aka – shout outs. –You can be responsible by… Staying organized and avoiding distraction. Staying focused on task completion. –You can make good choices by… Attending class regularly Doing your best and never giving up. –Be Safe! First, last, and always. Copyright © 2010 Ryan P. Murphy

3. Class Expectations –You can show respect by… Listening when the teacher or others are talking. –One speaker at a time, please raise your hand. Please no cross-room conversations during work time…aka – shout outs. –You can be responsible by… Staying organized and avoiding distraction. Staying focused on task completion. –You can make good choices by… Attending class regularly Doing your best and never giving up. –Be Safe! First, last, and always. Copyright © 2010 Ryan P. Murphy

4. Class Expectations –You can show respect by… Listening when the teacher or others are talking. –One speaker at a time, please raise your hand. Please no cross-room conversations during work time…aka – shout outs. –You can be responsible by… Staying organized and avoiding distraction. Staying focused on task completion. –You can make good choices by… Attending class regularly Doing your best and never giving up. –Be Safe! First, last, and always. Copyright © 2010 Ryan P. Murphy

5. Class Expectations –You can show respect by… Listening when the teacher or others are talking. –One speaker at a time, please raise your hand. Please no cross-room conversations during work time…aka – shout outs. –You can be responsible by… Staying organized and avoiding distraction. Staying focused on task completion. –You can make good choices by… Attending class regularly Doing your best and never giving up. –Be Safe! First, last, and always. Copyright © 2010 Ryan P. Murphy

6. Class Expectations –You can show respect by… Listening when the teacher or others are talking. –One speaker at a time, please raise your hand. Please no cross-room conversations during work time…aka – shout outs. –You can be responsible by… Staying organized and avoiding distraction. Staying focused on task completion. –You can make good choices by… Attending class regularly Doing your best and never giving up. –Be Safe! First, last, and always. Copyright © 2010 Ryan P. Murphy

7. Class Expectations –You can show respect by… Listening when the teacher or others are talking. –One speaker at a time, please raise your hand. Please no cross-room conversations during work time…aka – shout outs. –You can be responsible by… Staying organized and avoiding distraction. Staying focused on task completion. –You can make good choices by… Attending class regularly Doing your best and never giving up. –Be Safe! First, last, and always. Copyright © 2010 Ryan P. Murphy

8. Class Expectations –You can show respect by… Listening when the teacher or others are talking. –One speaker at a time, please raise your hand. Please no cross-room conversations during work time…aka – shout outs. –You can be responsible by… Staying organized and avoiding distraction. Staying focused on task completion. –You can make good choices by… Attending class regularly Doing your best and never giving up. –Be Safe! First, last, and always. Copyright © 2010 Ryan P. Murphy

9. Class Expectations –You can show respect by… Listening when the teacher or others are talking. –One speaker at a time, please raise your hand. Please no cross-room conversations during work time…aka – shout outs. –You can be responsible by… Staying organized and avoiding distraction. Staying focused on task completion. –You can make good choices by… Attending class regularly Doing your best and never giving up. –Be Safe! First, last, and always. Copyright © 2010 Ryan P. Murphy

10. Class Expectations –You can show respect by… Listening when the teacher or others are talking. –One speaker at a time, please raise your hand. Please no cross-room conversations during work time…aka – shout outs. –You can be responsible by… Staying organized and avoiding distraction. Staying focused on task completion. –You can make good choices by… Attending class regularly Doing your best and never giving up. –Be Safe! First, last, and always. Copyright © 2010 Ryan P. Murphy

11. Class Expectations –You can show respect by… Listening when the teacher or others are talking. –One speaker at a time, please raise your hand. Please no cross-room conversations during work time…aka – shout outs. –You can be responsible by… Staying organized and avoiding distraction. Staying focused on task completion. –You can make good choices by… Attending class regularly Doing your best and never giving up. –Be Safe! First, last, and always. Copyright © 2010 Ryan P. Murphy

12. Class Expectations –You can show respect by… Listening when the teacher or others are talking. –One speaker at a time, please raise your hand. Please no cross-room conversations during work time…aka – shout outs. –You can be responsible by… Staying organized and avoiding distraction. Staying focused on task completion. –You can make good choices by… Attending class regularly Doing your best and never giving up. –Be Safe! First, last, and always. Copyright © 2010 Ryan P. Murphy

13. Class Expectations –You can show respect by… Listening when the teacher or others are talking. –One speaker at a time, please raise your hand. Please no cross-room conversations during work time…aka – shout outs. –You can be responsible by… Staying organized and avoiding distraction. Staying focused on task completion. –You can make good choices by… Attending class regularly Doing your best and never giving up. –Be Safe! First, last, and always. Copyright © 2010 Ryan P. Murphy

15. How old are you? ? Copyright © 2010 Ryan P. Murphy

16. Answer: Billions of years old. Copyright © 2010 Ryan P. Murphy This Product Belongs to Ryan P. Murphy Copyright 2010

17. Answer: Billions of years old. –How? Copyright © 2010 Ryan P. Murphy This Product Belongs to Ryan P. Murphy Copyright 2010

18. The back story of our lives are that we are the product of billions of years of evolution. The very DNA that allows us to pass on our genetic information to our offspring has its roots in primitive microbes that existed billions of years ago. Copyright © 2010 Ryan P. Murphy

19. The back story of our lives are that we are the product of billions of years of evolution. The very DNA that allows us to pass on our genetic information to our offspring has its roots in primitive microbes that existed billions of years ago. Copyright © 2010 Ryan P. Murphy

20. DNA: Deoxyribose Nucleic Acid. DNA: Deoxyribose Nucleic Acid. Copyright © 2010 Ryan P. Murphy

21. Shape is called double helix. Shape is called double helix. Copyright © 2010 Ryan P. Murphy

23. DNA is a polymer (Long molecule). DNA is a polymer (Long molecule). Copyright © 2010 Ryan P. Murphy

24. DNA is a polymer (Long molecule). DNA is a polymer (Long molecule). Copyright © 2010 Ryan P. Murphy A tightly wound package of DNA.

25. Activity! How long is the DNA chain inside of a cell? –Take your best guess. Copyright © 2010 Ryan P. Murphy

26. Answer: The DNA in cells can hold lots of information and are very long. –Each cell has about 1.8 meters (6 feet) of DNA. 1.8 meters of DNA Copyright © 2010 Ryan P. Murphy

27. Video! DNA wrapping. Shows how 1.8 meters of DNA can be found in a single cell. –http://www.youtube.com/watch?v=AF2wwMReTf8http://www.youtube.com/watch?v=AF2wwMReTf8 Copyright © 2010 Ryan P. Murphy

28. The units of DNA are called nucleotides. The units of DNA are called nucleotides. Copyright © 2010 Ryan P. Murphy

29. DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

30. DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

31. DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

32. DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

33. DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

34. DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

35. DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

36. DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

37. DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

38. DNA through transcription makes mRNA. DNA through transcription makes mRNA. mRNA = Messenger RNA. mRNA = Messenger RNA. Copyright © 2010 Ryan P. Murphy

39. Transcription, Learn more at http://biology.about.com/od/cellularpro cesses/ss/Dna-Transcription.htm http://biology.about.com/od/cellularpro cesses/ss/Dna-Transcription.htm

40. mRNA through translation makes proteins with the help of ribosomes. mRNA through translation makes proteins with the help of ribosomes. Copyright © 2010 Ryan P. Murphy

42. Important Note: Most DNA is found in the nucleus.

44. Important Note: Most DNA is found in the nucleus. Small amounts of DNA are found in the mitochondria organelle (mtDNA) –Learn more abaout mtDNA at http://en.wikipedia.org/wiki/Mitochondrial_DNAhttp://en.wikipedia.org/wiki/Mitochondrial_DNA

45. Important Note: Most DNA is found in the nucleus. Small amounts of DNA are found in the mitochondria organelle (mtDNA) –Learn more http://en.wikipedia.org/wiki/Mitochondrial_DNAhttp://en.wikipedia.org/wiki/Mitochondrial_DNA

46. Watson and Crick (1953) Discovered structure of DNA. –One of the most important biological discoveries in the last 100 years. Copyright © 2010 Ryan P. Murphy

47. Watson and Crick (1953) Discovered structure of DNA. –One of the most important biological discoveries in the last 100 years. Copyright © 2010 Ryan P. Murphy

49. Watson and Crick were able to figure out that one strand went up and one went down.

52. Watson and Crick also found that if they paired Thymine with Adenine and Guanine with Cytosine DNA would look uniform.

53. Watson and Crick were able to figure out that one strand went up and one went down. Watson and Crick also found that if they paired Thymine with Adenine and Guanine with Cytosine DNA would look uniform. Learn more at… http://www.nobelprize.org/educa tional/medicine/dna_double_heli x/readmore.html?referer=www.cl ickfind.com.au

55. Please answer 3 of the 5 questions below from the difficult reading. –1.) Name four people in this article and how they contributed to the discovery of DNA’s structure? –2.) What role did Maurice Wilkins play in the discovery of DNA’s structure? –3.) What two things in DNA’s structure did Watson and Crick figure out that Rosalind Franklin missed? –4.) Describe the relationship between of Rosalind Franklin to Watson, Crick, and Wilkins? –5.) How does getting things done first / taking risks relate to this article? –6.) Find three words that you did not know from the reading and use a dictionary / resource to define them? –7.) Create a comic book sequence between Rosalind Franklin, Maurice Wilkins, James Watson, and Francis Crick from something discussed in the article.

56. Rosalind Franklin? Who is she? Copyright © 2010 Ryan P. Murphy

57. She took X-Ray pictures of DNA’s structure and lectured about phosphate being a part of the outside of the molecule. Copyright © 2010 Ryan P. Murphy

58. She took X-Ray pictures of DNA’s structure and lectured about phosphate being a part of the outside of the molecule. – Watson attended her lecture. Copyright © 2010 Ryan P. Murphy

59. Watson and Crick used her photograph and lectures to create a failed model of the helix. Copyright © 2010 Ryan P. Murphy

60. Watson and Crick used her photograph and lectures to create a failed model of the helix. –Maurice Wilkins who was working with Rosalind Franklin showed Watson her experiments. Copyright © 2010 Ryan P. Murphy

61. In 1962, Copyright © 2010 Ryan P. Murphy

62. In 1962, Watson, Copyright © 2010 Ryan P. Murphy

63. In 1962, Watson, Crick, Copyright © 2010 Ryan P. Murphy

64. In 1962, Watson, Crick, and Wilkins Copyright © 2010 Ryan P. Murphy

65. In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine. Copyright © 2010 Ryan P. Murphy

66. In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine. Copyright © 2010 Ryan P. Murphy

67. In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine. –Franklin had died of Ovarian Cancer. Copyright © 2010 Ryan P. Murphy

68. In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine, –Franklin had died of Ovarian Cancer. –The cancer that killed her may have been caused by working with X-Rays.

69. In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine, –Franklin had died of Ovarian Cancer. –The cancer that killed her may have been caused by working with X-Rays. –The Nobel Prize only goes to living recipients, and can only be shared among three winners.

70. Copyright © 2010 Ryan P. Murphy

76. Who thinks we should give an honorary Nobel Prize to Rosalind Franklin? Copyright © 2010 Ryan P. Murphy

77. Who thinks we should give an honorary Nobel Prize to Rosalind Franklin? –Lets give a short round of applause to Rosalind Franklin. –“Our Lady of DNA” Copyright © 2010 Ryan P. Murphy

78. Each unit called a nucleotide of DNA consists of 3 parts. Each unit called a nucleotide of DNA consists of 3 parts. - - - Copyright © 2010 Ryan P. Murphy

79. Phosphate backbone Phosphate backbone Copyright © 2010 Ryan P. Murphy

80. A AA G T C T T Phosphate Backbone Copyright © 2010 Ryan P. Murphy

81. A 5-carbon sugar (deoxyribose) A 5-carbon sugar (deoxyribose) Copyright © 2010 Ryan P. Murphy

82. A AA G T C T T Ribose Sugar Copyright © 2010 Ryan P. Murphy

83. A nitrogen base attached to the sugar A nitrogen base attached to the sugar Copyright © 2010 Ryan P. Murphy

84. A AA G T C T T Nitrogen Base Copyright © 2010 Ryan P. Murphy

85. A AA G T C T T Phosphate Backbone Copyright © 2010 Ryan P. Murphy

86. A AA G T C T T Ribose Sugar Copyright © 2010 Ryan P. Murphy

87. A AA G T C T T Nitrogen Base Copyright © 2010 Ryan P. Murphy

88. Video Link (Optional) DNA Khan Academy –http://www.khanacademy.org/video/dna?playl ist=Biologyhttp://www.khanacademy.org/video/dna?playl ist=Biology