1. LEHNINGER PRINCIPLES OF BIOCHEMISTRY
David L. Nelson and Michael M. Cox
LEHNINGER
PRINCIPLES OF BIOCHEMISTRY
Sixth Edition
CHAPTER 4
The Three-Dimensional
Structure of Proteins
© 2013 W. H. Freeman and Company

2. Peptide bond properties

3. The planar peptide group

4. Ramachandran Plot for L-Alanine residues

5. Models of the alpha helix

8. Alpha Helix Dipole

9. The beta conformation of polypeptide chains

10. Structures of beta turns

11. Trans and cis isomers of a peptide bond involving the imino nitrogen of proline

13. Ramachandran Plot for Pyruvate Kinase

15. Structure of hair

16. Permanent waving is biochemical engineering

17. Structure of collagen

18. Covalent crosslinks are present in collagen

20. Structure of Silk

21. Strands of silk emerge from the spinnerets of a spider

23. Examples of Motifs

24. Stable folding patterns in proteins

25. Constructing large motifs from smaller ones

26. Organization of Proteins Based on Motifs

27. Organization of Proteins Based on Motifs

28. Organization of Proteins Based on Motifs

29. Organization of Proteins Based on Motifs

30. Protein denaturation (unfolding) by heat or the chemical guanidinium hydrochloride (GdnHCl)

31. Renaturation (refolding) of unfolded, denatured ribonuclease
Anfinsen’s experiment from the 1950s

32. A hypothetical protein folding pathway for a small protein

33. Chaperones

34. Chaperones GroEL and GroES

35. Formation of disease-causing amyloid fibrils

36. Formation of disease-causing amyloid fibrils