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Published bySpencer O’Brien’ Modified over 9 years ago
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Chinese and Japanese are very similar in phenotype.
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Expression variation among Chinese and Japanese individuals Differently expressed Illumina's commercial whole genome expression array, Sentrix Human-6 Expression BeadChip version 2 These arrays utilize a bead pool with ~48,000 unique bead types Each with several hundred thousand gene-specific 50mer probes attached.
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Genome locations of 768 DE genes
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Functional enrichment of 768 DE genes
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Identify local (Cis) and distant (Trans) genetic regulators that associate with gene expression difference PopulationCis: # genes(snps)Trans: # genes(snps) CHB39 (306)271 (4544) JPT68 (648)92 (1216)
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CTSS vs cis-SNPs
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Dr. Shuhua Xu Yang ling, Lu dongsheng, Shi meng, Lou haiyi Jin wenfei, Pankaj All in population genomics group
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