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Overview of the Inc 29-30 Experiments supported by CADMOS Hélène RUGET - Maurice MARNAT.

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Presentation on theme: "Overview of the Inc 29-30 Experiments supported by CADMOS Hélène RUGET - Maurice MARNAT."— Presentation transcript:

1 Overview of the Inc 29-30 Experiments supported by CADMOS Hélène RUGET - Maurice MARNAT

2 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 2 CADMOS Ops Leads Team Ops LeadExperiments Alain MailletSOLO, CARD, EPM, DOSIS-3D, MARES, ENERGY* Hélène RugetMARES, SOLO, NEUROSPAT, EPM, DOSIS-3D, CARD, PASSAGES, ENERGY* Cécile ThevenotSOLO, CARD, EPM, DOSIS-3D, PASSAGES, ENERGY* Stéphanie HerrCARD, PASSAGES, NEUROSPAT, SOLO, MARES, ENERGY* Maurice MarnatPASSAGES, NEUROSPAT François NuyttensSOLO, NEUROSPAT, MARES Nicolas SprengerDOSIS-3D Romain CardotNew person arrived at CADMOS in 2011: will enter in certification process Lourdes Oro MarotNew person arrived at CADMOS in 2011: will enter in certification process Stéphanie Maurice François Hélène Cécile Alain Nicolas Romain Lourdes *ENERGY: certification ongoing

3 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 3 Increment 29-30 (Inc 31-32) CARD: Investigating Mechanisms of Heart Disease (support to DAMEC) SOLO: Sodium retention in microgravity PASSAGES: Scaling Body-Related Actions in Absence of Gravity IMMUNO: Neuroendocrine and immunological changes NEUROSPAT: Prefrontal brain functions and spatial cognition ENERGY: Astronaut’s energy requirements for long-term space flights MARES: Commissioning part 1 BDC only: EDOS: Early Detection of Osteoporosis in Space (ground only) SPIN: Centrifugation, static tilt and orthostatic tilt tests (ground only) “Specials”: DOSIS-3D: Dose Distribution inside ISS (support to MUSC) ICV: Integrated Cardiovascular (support to NASA-ICV for Cardiopres) VESSEL IMAGING: Vascular Imaging (support to DAMEC) MARES : troubleshooting (support to NASA-HRF) Experiment Support

4 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 4 Science overview Experiment that intends to test: 1.How the cardiovascular system adapts to prolonged weightlessness and whether the arterial resistance vessels are chronically dilated in space. 2.Whether there is a mismatch between the level of sympathetic nervous activity and dilatation of these vessels. Main Hardware Pulmonary Function System (Cardiac output - DAMEC) CDL Holter Arterial BP Equipment (24h BP measurements - CADMOS) Blood Sample Kit, ESA Urine Collection Kit (CADMOS), HRF-2 RC and MELFI Subjects (6 desired, 8 preferred) Inc 29-30: E. Kuipers (prime - #8 will be the last subject), N.Pettit (Reserved– pending ICB approval) Implementation 1 in flight session per subject, preferably after 3 months on-orbit, minimal 2 months. Crew time Day 0: 10 min (CDL Holter batteries insertion) Day 1: 175 min ( EPM laptop activation for Holter configuration, PFS S/U, Holter S/U, Start of 24hr urine collection, 3 PFS measurements, Holter data saving) Day 2: 240 min (Blood collection, RC, MELFI insertion, end of urine collection, urine sampling and MELFI insertion, 2 PFS measurements, Holter data saving, stowage) Data Holter data / Urine Log stored on PCMCIA card – downlink to ground via EPM Photo / Video Video of one rebreathing session CARD

5 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 5 Sodium retention in microgravity Science overview Study the impact of diet period on fluid and salt retention. Main Hardware EPM Laptop for PCBA SW update CDL Holter Arterial BP Cable for PCBA SW update PCBA: Portable Clinical Blood Analyzer MELFI: Freezer HRF2/RC: Refrigerated Centrifuge HRF1/SLAMMD: space weight-scale Consumables for Blood and Urine samples Next subjects Inc 29-30: D. Burbank (Reserved), A. Kuipers Implementation 2 sessions per subject, 6 days activities /session L + 30 days < session 1 < 0 to 7 days < session 2 < R – 30 days Crew time Day 1, 2, 3, 4 & 5 : diet monitoring Day 4 & 6 : body mass measurement with SLAMMD Day 5 : blood collection and PCBA measurement Day 5 & 6 : 24hrs urine collection Data Data record in logs (diet, PCBA, urine) Data downlink to ground (SLAMMD) Blood and urine samples download to ground (frozen) SOLO

6 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 6 Scaling Body-Related Actions in Absence of Gravity Science overview Stand-alone experiment. Subject quasi free floating uses a tunnel (lighshield) to immerge into a virtual corridor and evaluate « passability » through doors. Main Hardware Laptop, lightshield, trackball, PCMCIA card Next subjects Inc 29-30: M. Fossum S. Furukawa, D. Burbank (reserved) Next Increment: J. Acaba, S. Williams, A. Hoshide Implementation 2 sessions per subject (Before FD21 and after FD120) Crew time 100 min crew time / session Data Data stored on PCMCIA card – downlink to ground via EPM Photo / Video 5 min video required PASSAGES

7 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 7 Astronaut’s energy requirements for long-term space flights Science overview Measure energy requirements before and during long-term space flight (>90 days), through doubly labeled water (DLW) intake to measure total energy expenditure (TEE) and body composition Main Hardware PFS (in HRF2) including MBS system,PFS Face Mask Kit, Energy kit, Energy Armband Kit, Energy Food Kit, Energy Urine Collection Kit, Energy Sample Kit, Energy Armband Consumable Kit, Energy Ultrabay Wallet, Water Sampling Kit, Energy Water Kit,Urine Containment Bag Kit Next subjects Inc 29-30: A.Kuipers, N.Pettit Implementation 1 session of 11 days after 3 month in space Crew time Under USOS resources. 5.83hrs for PFS + 4.83hrs for ENERGY stand-alone, per test subject. Control: 3hrs Data Samples downloaded at ambient temperature, data downlinked via EPM Photo / Video N/A ENERGY

8 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 8 Science overview Stand alone experiment to study how human psycho-neuroendocrine and immunologic systems adapt to space environment, and how these processes are dependent on the cellular level of signal processing Main Hardware Plasma03 centrifuge MELFI freezer Stress Test paper sheets, Saliva-Immuno kit, MBI Defence kit, Plasma 03 kit. Next subjects 2 Russian crew members Implementation First session during quiet period between L+3months +/-30 days Second session during L+5months and R-2weeks Crew time 5h15min/session (24h session from 8am to 8am) Day 1: Stress Tests, Saliva Samplings, Blood Sampling Data Blood samples (frozen), paper Current Stress tests sheets, blood smears boxes and saliva tubes, blood sampling logbooks. Photo / Video Pictures of inflight operations: nice to have for presentation purpose. Neuroendocrine and immune responses during and after long term stay at ISS IMMUNO

9 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 9 Prefrontal brain functions and spatial cognition Science overview Subject in free floating using a tunnel (lighshield) to immerge into challenging scene. EEG, EOG, EMG and ECG signals are acquired via EPM-MEEMM. Main Hardware EPM, MEEMM, laptops, lightshield, gamepad, EEG cap, consumable (gel), chest belt Next subjects Inc 29 – 30 A. Kuipers (N. Pettit operator), Next increment: A. Hoside (Williams operator) Implementation 2 sessions per subject (around FD15 and FD60) 3 days activities /session Crew time Day 1 : hardware setup Day 2 : electronic hardware activation, EEG cap setup, experimental session, quick stowing Day 3 : data saving, stowing Data Data stored on MEEMM and laptop Neurosciences Hard Disks Data downlink via EPM High Rate link Photo / Video 5 min video required, photo-modeling pictures of EEG cap NEUROSPAT

10 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 10 Muscle Atrophy Research and Exercises System: C/O Part 1 Science overview N/A: Commissioning Part 1 = functional test of MARES Main Hardware MARES, EPM Laptop & Ext. HD, EPM Rack Next subjects Inc 30: A. Kuipers Implementation 2 days activities Crew time 6h45mn of crew time Day 1 : MARES deployment + VIF test + activation + Battery charge + Files load + Spare HD test Day 2 : HW activation + Functional test session + Files copy + Battery discharge + deactivation/stowage/ + Files downlink to ground Data Data stored on MARES and EPM Laptop Data downlink via EPM High Rate link Photo / Video Video required for Day 1 and Day 2 MARES

11 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 11 Overview ExperimentsPre-flightPost-flight ENERGY Between L-150 and L-30 d DEXA scan b/w L-365d and L0 Body mass before launch Body mass between R+0 and R+7d DEXA scan between R+0d and R+1y CARD Any time before L> R+60d IMMUNO Between L-30d/L-7dR+1 or R+2, R+7, R+20-30 NEUROSPAT L-90d, L-60d, L-30d.R+2, R+6, >R+15 (x2) PASSAGES >L-90dR+1d, >R+20d SOLO N/A>R+6M EDOS L-60d, L-30d R+1d (BM), R+2d (XCT), R+15d (BM), R+90d(BM & XCT), R+180d (BM & XCT), R+360d ±2w SPIN <L (x3) the same Wk R+1d, R+4d, R+9d: VVIS and Tilt test BDC

12 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 12 ACRONYMS ADASAmbulatory Data Acquisition SystemHRFHuman Research Facility BPBlood PressureMARESMuscle Atrophy Research and Exercise System CDLCardiolabMEEMMMulti ElectroEncephalogramme Mapping Module ECGElectrocardiogrammeMELFIMinus Eighty Degree Laboratory Freezer for ISS EEGElectroencephalogrammePCBAPortable Clinical Blood Analyzer EMGElectromyogrammePEMS-2Percutaneuous Electrical Muscle Stimulator 2 EOGElectrooculogrammeRCRefrigerated Centrifuge EPMEuropean Physiology Modules FacilitySWSoftware HDHard DiskVUVideo Unit

13 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 13 Back up slide

14 POIWG#30_CADMOS-Inc29-30 Overview I July. 26-28. 2011 I Huntsville, AL I Page 14 Muscle Atrophy Research and Exercises System: C/O Part 2 Science overview N/A: Commissioning Part 2 = operational test of MARES Main Hardware MARES, EPM Laptop & Ext. HD, PEMS-2, EMG device, HRF Echo, consumables, EPM Rack Next subjects TBD (one subject + one operator) Implementation 4 days activities Crew time Day 1 : MARES deployment + activation + Battery charge + PEMS test + Ultrasound activity Day 2 : Subject equipment (PEMS-2 + EMG electrodes) + HW activation + Com Part 2 session + Files copy + Battery discharge + deactivation/stowage/ + Files downlink to ground Data Data stored on MARES and EPM Laptop Data downlink via EPM High Rate link Photo / Video Video required for Day 1 and Day 2 MARES

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