1. ANZDATA Registry Annual Report 2013 Philip Clayton CHAPTER 9 KIDNEY DONATION 2013 Annual Report - 36th Edition DEATHS CHAPTER 3

2. ANZDATA Registry Annual Report 2013 Figure 3.1 Survival among People who Commenced Dialysis 2003 - 2012 (Non-Indigenous) % (95% CI) Age at Start Time Point (Number of Years from dialysis start) Proportion Surviving Aust (95 % CI) Proportion Surviving NZ (95 % CI) 0– 24 1 97 (95-98)96 (90-99) 2 93 (90-95)93 (85-97) 5 90 (86-93)83 (64-92) 25—44 1 97 (96-98)98 (96-99) 2 92 (90-93)93 (89-96) 5 80 (78-83)74 (65-81) 45—64 1 92 (91-92)91 (89-92) 2 85 (84-85)81 (78-84) 5 61 (59-62)54 (49-58) 65—74 1 86 (85-87)85 (82-87) 2 74 (72-75)72 (69-76) 5 42 (41-44)34 (30-39) 75—84 1 80 (79-81)77 (72-81) 2 64 (63-66)56 (51-61) 5 28 (26-29)19 (15-24) 85 + 1 70 (66-74)67 (46-80) 2 51 (47-56)45 (28-61) 5 20 (15-24)17 (5-34)

3. ANZDATA Registry Annual Report 2013 Figure 3.2 Death Rates During Renal Replacement Therapy All Patients Included who Received Treatment During 2012 Group Dialysis Mortality Rate (per 100 patient years, 95% CI) Transplant Mortality Rate (per 100 patient years, 95% CI) Overall Rate Confidence Intervals Rate Confidence Intervals Per 100 patient years LowerUpper Per 100 patient years LowerUpper Australia 12.712.213.41.81.62.1 New Zealand 14.613.216.21.91.32.8 A GES (Y EARS ) < 25 3.72.07.00.40.11.5 25—44 4.93.96.10.50.30.8 45—64 9.38.510.21.41.11.8 65—84 17.116.118.25.14.16.2 ≥ 85 36.531.642.12.15.48.6 D IABETES ( AT RRT START ) Non-diabetic 11.210.612.11.71.42.0 Type 1 12.19.616.82.71.74.4 Type 2 15.514.616.63.12.04.9 C ORONARY ARTERY DISEASE ( AT RRT START ) No 9.99.310.61.71.52.0 Yes 19.017.820.33.12.04.7 I NDIGENOUS Non-Indigenous (Aus) 13.512.814.31.81.52.1 Non-Indigenous (NZ) 15.713.518.31.81.22.8 Aboriginal /Torres Strait Islanders 9.07.510.73.21.47.1 Maori (in Aus) 9.04.916.83.40.523.8 Maori (in NZ) 16.413.819.62.50.96.7 Pacific People (in Aus) 6.54.110.31.30.29.1 Pacific People (in NZ) 10.27.913.22.10.58.5

4. ANZDATA Registry Annual Report 2013 Figure 3.3

5. ANZDATA Registry Annual Report 2013 Figure 3.4

6. ANZDATA Registry Annual Report 2013 Figure 3.5 Survival of Dialysis Patients by Age Age Groups at start of treatment Median (25th and 75th centiles), years Australia 0-24 years* 25-44 years* (5.35-*) 45-64 years6.35 (3.09-*) 65-74 years4.18 (1.90-7.23) 75-84 years3 (1.31-5.32) 85+ years 2.03 (0.76-4.02) New Zealand 0-24 years9.64 (8.11-*) 25-44 years7.28 (4.11-*) 45-64 years5 (2.65-8.41) 65-74 years3.65 (1.84-5.93) 75-84 years2.61 (1.08-4.37) 85+ years 1.70 (0.96-3.58)

7. ANZDATA Registry Annual Report 2013 Figure 3.6 Survival by Age & Comorbidity Amongst Older Age Groups Median (25th and 75th centiles), years Age Groups Any Vascular Disease DiabetesAustralia New Zealand 65-69 yearsNo 5.32 (2.04-*) 6.01 (2.67-7.68) NoYes3.95 (1.93-8.29) 5.23 (4.20-8.69) YesNo4.30 (2.08-7.04) 2.36 (0.87-4.81) Yes 4.31 (2.05-6.96) 4.03 (1.41-4.27) 70-74 yearsNo 5.37 (2.03-8.37) 3.40 (3.12-5.37) NoYes5.89 (3.23-8.38 ) 3.33 (2.27-4.41) YesNo3.46 (0.96-5.81) 2.55 (1.63-4.45) Yes 3.65 (1.80-5.97) 3.33 (1.78-4.88) 75-79 yearsNo 5.47 (2.14-8.31) 3.43 (3.43-3.43) NoYes5.59 (2.39-*) 3.92 (3.92-4.39) YesNo4.00 (1.85-6.35) 1.42 (0.57-2.43) Yes 3.08 (1.04-5.48) 2.97 (1.49-5.74) 80-84 yearsNo 3.41 (2.02-6.21) 2.69 (1.65-3.01) NoYes4.34 (2.70-6.17) 0.67 (0.67-0.67) YesNo2.28(1.02-4.90) 4.10 (1.04-4.10) Yes 2.37 (1.29-4.55) 2.82 (2.82-2.82) 85-89 yearsNo 2.25 (0.63-7.79) * NoYes2.39 (0.63-*) * YesNo2.17 (1.32-3.58) 1.38 (1.38- 4.91) Yes 1.57 (0.36-6.09) *

8. ANZDATA Registry Annual Report 2013 Figure 3.7

9. ANZDATA Registry Annual Report 2013 Figure 3.8

10. ANZDATA Registry Annual Report 2013 Figure 3.9

11. ANZDATA Registry Annual Report 2013 Figure 3.10

12. ANZDATA Registry Annual Report 2013 Figure 3.11 Modality at Time of Death and Age at Death – 2012 Cause of Death Haemodialysis Peritoneal Dialysis Transplant 0 - 4445 - 6465 - 74≥75 0 - 4445 - 6465 - 74≥75 0 - 4445 - 6465 - 74≥75 Australia Cardiovascular19113101147 5171329 214207 Withdrawal156788248 2132034 2374 Cancer2171434 0513 225156 Infection2283034 07513 525156 Other147358110 781727 215117 New Zealand Cardiovascular11412414 0241613 1425 Withdrawal4141314 17810 0001 Cancer1330 0231 0531 Infection3835 1351 0210 Other2272212 116109 0310

13. ANZDATA Registry Annual Report 2013 Figure 3.12 Country at time of Death and Modality at Death Among Those Who Withdrew From Dialysis and Died in 2012 Cause of Death AUSTRALIA NEW ZEALAND HDPDGRAFT HDPDGRAFT Cardiovascular3806443 905312 Withdrawal4186916 45261 Cancer67948 769 Infection942524 19103 Other2555935 63364

14. ANZDATA Registry Annual Report 2013 Figure 3.13 Death Due to Withdrawal - 2012 (Modality at Time of Death) WithdrawalHaemodialysisPeritoneal DialysisTransplantTotal Australia Psychosocial163267196 Patient refused further204428 Suicide5016 Cardiovascular comorbidity8113094 Cerebrovascular comorbidity4310154 Peripheral vascular comorbidity312033 Malignancy related withdrawal6311077 Withdrawal due to dialysis123015 Total4186916503 New Zealand Psychosocial1510025 Patient refused further4206 Suicide0000 Cardiovascular comorbidity55111 Cerebrovascular comorbidity86014 Peripheral vascular comorbidity8109 Malignancy related withdrawal4105 Withdrawal due to dialysis1102 Total4526172

15. ANZDATA Registry Annual Report 2013 Figure 3.14 Dialysis patients who withdrew by age at death time from first RRT-2012 Time from first RRT (years) AUSTRALIA NEW ZEALAND 0 - 4445 - 6465 - 74≥75Total 0 - 4445 - 6465 - 74≥75Total 0219164986 23319 1215133666 133613 27154896166 277824 583438105185 0881026 Total1983115286503 521 2572

16. ANZDATA Registry Annual Report 2013 Figure 3.15

17. ANZDATA Registry Annual Report 2013