1. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Human Research Program (HRP) Lyndon B. Johnson Space Center Increment 27/28 Overview Increment Manager John Love/NASA Increment Lead Gina Miller/ LM Operations Lead Blue Bradley/ LM

2. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley HRP Team NASA Increment Manager John Love 281-483-7713 john.e.love@nasa.gov Increment Lead Gina Miller 281-218-3016 gina.miller@lmco.com Increment Operations Lead Blue Bradley 281-218-3248 jonathan.b.bradley@lmco.com Increment Scientist Deb Harm, Ph.D. 281-483-7222 deborah.harm-1@nasa.gov Increment Planner Jamie Rukab 281-218-3224 jamie.rukab@lmco.com Increment Training Coordinator Joyce Schultz 281-218-3051 joyce.e.schultz@lmco.com Lyndon B. Johnson Space Center 2

3. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley AGENDA HRP Payload Complement Investigation Summary Crew Participation New HRP Activities Implementation Details Facility Operations/Support Deltas from last POIWG presentation Assumptions/Risks Open Work 3

4. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Investigations Previous Increments Bisphosphonates18-25/26 Functional Task Test (Pre-/Post only)22-25/26 Integrated Cardiovascular19/20-25/26 Integrated Immune16-25/26 Nutrition14-25/26 Pro K21/22-25/26 Reaction Self Test21/22-25/26 Repository16-25/26 Spinal Elongation 20-25/26 SprintNew Treadmill KinematicsNew UMS Rollover VO2Max20-25/26 HRP Increment 27-28 Complement 4

5. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Bisphosphonates: Adrian LeBlanc, Ph.D., Toshio Matsumoto, M.D., Ph.D. –Countermeasure to in-flight loss of regional bone density –In-Flight Data Collection: Weekly Alendronate Pill Ingestions and urine collections in conjunction with some NUTR/Repo/PROK collections Functional Task Test: Jacob Bloomberg, Ph. D Develop set of functional and physiological tests to determine how postflight changes in sensorimotor, cardiovascular, and muscle physiology impact functional performance –Data Collection: Pre-/Post-flight testing only; series of timed muscle performance test Integrated Cardiovascular: Benjamin D. Levine, M.D., Michael W. Bungo, M.D. –Quantify the extent, time course and clinical significance of cardiac atrophy (decrease in the size of the heart muscle) associated with long-duration space flight. This experiment will also identify the mechanisms of this atrophy and the functional consequences for crewmembers who will spend extended periods of time in space. –In-Flight Data Collection: Hardware used: HRF Ultrasound, HRF Actiwatch, HRF Holter Monitor 2, ESA Cardiopres. 48 Hr Ambulatory Monitoring within 1 week of Ultrasound scan. Investigation Summary 5

6. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Integrated Immune: Clarence Sams, Ph.D. –Assess the clinical risks resulting from the adverse effects of space flight on the human immune system and will validate a flight-compatible immune monitoring strategy. –In-Flight Data Collection: Blood and Liquid/Dry Saliva Samples, ambient return Nutrition: Scott M. Smith, Ph.D –Measures bone metabolism, oxidative damage, chemistry and hormonal changes, as well as assessments of the nutritional status of the astronauts participating in the study. –In-Flight Data Collection: Blood and 24-Hr urine samples, Food Frequency Questionnaire Pro K: Scott M. Smith, Ph.D. –Evaluation of a dietary countermeasure to lessen bone loss of astronauts. Pro K proposes that a flight diet with a decreased ratio of animal protein to potassium will lead to decreased loss of bone mineral. –In-Flight Data Collection: Controlled/monitored diet with urine and blood samples Investigation Summary 6

7. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Repository: Kathleen McMonigal, M.D. –The National Aeronautics and Space Administration Biological Specimen Repository is a storage bank that is used to maintain biological specimens over extended periods of time and under well-controlled conditions. –In-Flight Data Collection: additional tubes collected in combination with NUTR study blood draw Reaction Self Test: David F. Dinges, Ph.D. –Short task to evaluate reaction times which will monitor the daily effects of fatigue on performance while on board the International Space Station. –In-Flight Data Collection: Testing using reaction feedback software, scheduled on specific days and sleep shifted schedules, and around EVAs. Spinal Elongation: Sudhakar Rajulu, Ph.D. –Provide quantitative data as to the amount of change that occurs in the seated height due to spinal elongation in microgravity. –In-Flight Data Collection: Seated Height and Standing Height logs, photo documentation. Data collected on shuttle using CDR chair. Investigation Summary 7

8. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Sprint: Lori Ploutz-Snyder, Ph.D. –Evaluate a new integrated resistance and aerobic training program designed to minimize the loss of muscle, bone, and cardiovascular function during ISS missions. –In-Flight Data Collection: Monitoring of training loads on ARED and T2 will be evaluated as assessment of muscle function. Cardiovascular fitness assessment will include a monthly measurement of VO2max. Muscle response in flight will be measured via ultrasound scans of muscle tissue. Subjects will perform the Sprint exercise prescriptions 6 days per week in flight, beginning as early as possible. Treadmill Kinematics: John K. De Witt, Ph.D. –Collect biomechanical data during treadmill exercise on the ISS to determine the appropriate speed and load combinations that may be the best to maintain bone and muscle health. –In-Flight Data Collection: Visual markers will be placed on the crewmember’s body and high definition video will be recorded and downlinked to be analyzed on the ground. Specific exercise prescriptions for each session will be available to the crew, which they will input manually into Treadmill 2. VO2max: Alan D. Moore, Jr., Ph.D. –Documents changes in maximum oxygen uptake for crewmembers onboard the ISS on long-duration missions. –In-Flight Data Collection: Maximal exercise portion added to monthly PFE using ESA Portable PFS Investigation Summary 8

9. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley InvestigationNespoli 25S FE5 (ESA) Coleman 25S FE6 Garan 26S FE3 Fossum 27S FE6 Furukawa 27S FE5 (JAXA) BisphosphonatesWeekly Pill Ingest; Urine – sample share, photo Weekly Pill Ingest; Urine – sample share Integrated Immune Late ( 25S) Immn Survey Early(ULF-6), Mid ( 25S or ULF-7), and Late ( 26S) Immn Survey, Photos** Early ( ULF-7), Mid (26S) Immn Survey Photos** Early ( ULF-7), Mid (26S) Immn Survey Photos** Integrated Cardiovascular Operator Only2 Sessions - FD 135, R-15 * Operator Only 3 Sessions - FD 14, 30, & 75; Photos** Nutrition/Rep2 Sessions (FD 120,180) 2 Sessions (FD 120, 180) 5 Sessions (FD 15, 30, 60, 120, 180)Photos** 3 Sessions (FD 15, 30, 60) Photos** 3 Sessions (FD 15, 30, 60) Photos** Pro K2 Sessions – see NUTR Reaction Self Test4.58 hrs 13.25 hrs Photos** 8.5 hrs Photos** 8.5 hrs Photos** Spinal ElongationULF-6 operator HRP ISS Crew Participation * Coleman FD135 and R-15 sessions close together** Reserve 9

10. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley InvestigationNespoli 25S FE5 (ESA) Coleman 25S FE6 Garan 26S FE3 Fossum 27S FE6 Furukawa 27S FE5 (JAXA) Sprint7 USND sessions (FD15, 30, 60, 90, 120, 150, R-7) * Treadmill Kinematics 1 st subject. 6 sessions. FD15, 45, 75, 105, 135, R-15. 4 sessions. FD15, 45, 75, 105. UMS – Validation & Checkout Subj Checkout OpsValidation, Subj Checkout Ops Subj Checkout Ops VO2 Max2 Sessions. FD 135, R-30 6 sessions. FD 15, 45, 75, 105, 135, R-30 4 sessions. FD 15, 45, 75, 105 HRP ISS Crew Participation * VO2max will data share with Sprint – 6 sessions 10

11. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley HRP Shuttle Complement ULF6 / STS-134 –Spinal Elongation  Seated Height only, no photo downlink Req'd  Only STS Subjects: CDR & PLT with Coleman or Nespoli as OPR  HW comes home on this flight –Sleep Short  STS Subjects: PLT, MS2, MS4 ULF7 / STS-135 –Sleep Short  STS Subject: MS2 11

12. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Urine Monitoring System (UMS) UMS is an automated void volume measurement and sample acquisition system UMS operations will include: –Assembly & Validation –Nom Check-out Ops (Subject Req’d) UMS Validation will include volume confirmation and analysis of pre- positioned non-biological samples flown on 19A UMS Nom Check-out Ops will include two subjects’ 2-day urine collection periods UMS Samples will return on ULF7 The ISS Urine Monitoring System (UMS) is an upgrade to the previous Shuttle UMS that is capable of: 1) Collecting and accurately measuring void volume 2) Separating urine from air 3) Allowing acquisition of individual, uncontaminated urine samples. PI: Mark Clarke, Ph.D. 12

13. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley UMS arrives on ULF5 UMS Adapter Hose to arrive on ULF-6 (to bypass A2 connector) Will be set up in the Waste & Hygiene Compartment (WHC) in Node 3 Requires the use of an SSC; UMS software load to be part of nominal SSC load for ULF-6 –Node 3 specific SSC requested to ensure power allotment –Data transfer via wireless LAN to ops server for OCA Downlink –Required for Validation, Checkout, and for later nominal payload operations Urine Monitoring System (UMS)  UMS ECR submitted during Inc 25/26  UMS Realtime Ops Target: ULF-6 stage  Driver for Ops: Sample return protected on ULF7 Notable 13

14. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley UMS power and water resources are accounted for by WHC allotment –UMS will not operate unless the WHC is functioning nominally –UMS will not operate during potable water bus testing, troubleshooting, etc –UMS will follow WHC ACY Fan constraints: 30 min run time with 20 min cool down period between uses OIP needs to be written – OSO action from UMS telecon Oct. 2010 due to OSO ownership of WHC Urine Monitoring System (UMS) 14

15. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Forward Work –Work with POIC/PLUTO to identify SSC for use inside the WHC for the timeframe of the collections (for the initial “commissioning” – Val/C-O and later for nominal payload collections) –The Emerald brick from SSC20 is specifically allocated for Shuttle middeck flight activities, so if our ops are NOT during docked ops – this is our best bet at getting the emerald brick reqmt filled. –Maintenance flushes of UMS may be required and need to be scheduled at a TBD frequency. Urine Monitoring System (UMS) 15

16. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley HRF Supply Kit – Up on ULF-5 HRF Rack2 Drawer Locations to be called out in Stowage Notes for HRF activities only –HRF Supply Kit Purple: COL1A4_D1/E1 –HRF Supply Kit Green: COL1A4_G1/H1 HRF Supply Kits will have Increment specific activities –HRF Initial Configuration (HW up on ULF-5) will insert 8PU Drawer Liners and stock consumables according to schematics, and take photos one time –Resupply activities will remove limited life items, restock consumables and take photos of final configuration as needed. Plan once per Inc. –Inventory activities will report consumable quantities and take photos  HRF Supply Kit Resupply IPV Procedure will utilize “strike-through” font to remove steps not required  HRF Inventory Excel file will be completed and attached to the OSTPV activities by the crew Notable 16

17. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Actiwatch Spectrum Operations S. Kelly last Sleep subject. Coleman using existing HW and SW for Integrated Cardiovascular. Old HW will transition to use for Med Ops Actigraphy. ICV Operations starting with Furukawa (mid-June) New software is compatible with both the new hardware and the old hardware Hardware is exclusive – new reader only reads new watches  Planned OCR to transition products to AWS  Med Ops to use old Actiwatches and Actiwatch Reader for Actigraphy Notable 17

18. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Treadmill Kinematics Operations Use existing activities for video downlink –G1 Camcorder configuration if required (not expected) – linked inside Treadmill Kinematics procedure –MPC downlink for high definition video to ground Exercise prescriptions to be uplinked in message via OCR for each session. Crew will input exercise prescription manually on the T2 control panel  OCR to uplink exercise prescription for EACH session Notable 18

19. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Sprint Operations Use existing activities and products for VO2max portion VO2max unchanged, will data share with Sprint New procedures for USND scans to be baselined via ECR First subject 27S FE6 (Fossum) First session with remote guidance. Subsequent scans to be assisted as deemed necessary. Forward Work – T2 may not be able to achieve speeds necessary. Increased harness loads have been proposed to assist in achieving target heart rate. 19

20. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Sprint Operations The in-flight life of a Sprint subject 20

21. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Current Implementation Details  Support during IP Science use of HRF Hardware will only include a HRF Systems Engineer on console for direction of safe and consistent use of the HRF Hardware; no science or stowage calls should be expected from the HRF Console  Direct communication with the crew, when available, is required during the Calibration and Instrument check of VO2max sessions to answer calldowns regarding hardware anomalies. Already a GR&C and proposed ULF-6 Payload Reg.  HRP has a contract with Med Trainers to support blood draws. S/G will be tied to private loop prior to activity to allow for crew calldowns regarding the blood draws  OCA downlinks: OC to write IFN to action OCA officer to perform downlinks per timeline.  Proprietary or sensitive information should not be included in crew notes, IPV state data, or other public avenues of communication  OCA Downlink of restricted data will go from OC to OCA to TSC drop box, photos via Bldg 8 Notable 21

22. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Current Implementation Details  Bisphosphonates Pill Ingestion constraint reminders can be voice up or given in Daily Summary. 25S FE6 requested callup reminders of constraints.  Nutrition/Repository/Pro K 24-hr urine collections can be scheduled over the weekend to allow flexibility in timeline management and will start with the first morning void on a given day and end with the void collection after 24-hrs has passed from the initial void. 26S FE3 must have blood OPR, per request.  Crew preference for restraint during scan (e.g, CMRS or “bear hug” method) will be communicated to the COL Flight Planning team for awareness of CMRS in Columbus.  ICV Ambulatory Monitoring can start on a Friday to minimize interference with finger-cuff data collection.  Crew preference for Integrated Immune dry saliva collection reminders – 27S FE6 requested they be hard scheduled.  Crew Preferences concerning 24-hr Urine Collection scheduling, constraint reminders, Pill Ingestion scheduling, configuration states will be identified in Crew Increment Status Briefings and relayed to POIC for documentation in stage payload regulations Notable 22

23. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley HRP Facility Activities GDS/PFS Gauge Photos SLAMMD BMM & Control Run HRF Supply Kit Resupply & Inventory HRF Facility Support for IP & MedOps RC Support for Card/Solo/Vascular PFS Support for Card SLAMMD Support for Solo USND Support for Ocular Scans USND Support for Vessel Imaging EKE & Thermolab (with VO2 Max) Med Ops Actigraphy* * Sleep study concluded in Increment 25/26 with S. Kelly. No nominal console support for Med Ops Actigraphy 23

24. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Section A ESA does initial WFSV settings to ~ 27kg/hr –COLOC can command the WFSV via S-Band and does not require KU-Band) Section B Section B involves PRO, COL OC, and HRF commanding to enable session specific payloads. KU&S will be required for this section. PRO sends command to enable polling ESA applies power to HRF Rack ESA enables Smoke detection monitoring HRF sets Subset ID for Rack HRF loads Configuration Files HRF sets Rack to Operational Mode HRF Configures Subsystem Valve ESA adjusts WFSV for activity (Flow Cases B-E) HRF Configures Payload Valves (if needed) HRF configures Rack for activity New Activation: Option A 30 Minutes BA HRF- RACK- PWRUP PRO-HRF-ACT CMD ESA-HRF- WFSV ESA-HRF-ACT Variable Length With at least 45 minutes of KU&S Coverage 24

25. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Section A ESA does initial WFSV settings to ~ 27kg/hr –COLOC can command the WFSV via S-Band and does not require KU-Band) Section B Section B involves PRO, COL OC, and HRF commanding to enable session specific payloads. KU&S will be required for this section. PRO sends command to enable polling ESA applies power to HRF Rack ESA enables Smoke detection monitoring HRF sets Subset ID for Rack HRF loads Configuration Files HRF sets Rack to Operational Mode HRF Configures Subsystem Valve ESA adjusts WFSV for activity (Flow Cases B-E) HRF Configures Payload Valves (if needed) HRF configures Rack for activity New Activation: Option B 30 Minutes B A ESA-HRF- WFSV Variable Length With at least 45 minutes of KU&S Coverage PRO/ESA/HRF- HRF#-ACT 25

26. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Delta: Actiwatch Spectrum (AWS) Targeted 1 st Subject to wear the new Actiwatch Spectrum hardware change from Coleman to Furukawa, to prevent possible switchover in the middle of data collection (both BDC and inflight collection) Actiwatch System to change out “Legacy” Actiwatch for new “Spectrum” Actiwatch; software update required also. Med Ops will use old hardware for Actigraphy New software is compatible with both old and new hardware. AWS HW and new SW up on ULF-5  AWS Transition will occur in Inc 27 for Furukawa’s FD15 ICV session; OCR to be submitted by Inc 27/28 team Notable 26

27. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Delta: T61p Transition T61p Transition from A31p target implementation date delayed (Inc 27/28) due to SW load going up on ULF-5. T61p Transition ECR products delivered, products will be baselined before start of Inc 27/28 Actual hardware transition to occur after ULF-5 arrival.  T61p Transition implementation for HRF PC1 and HRF PC2 date is double booked for Inc 25/26 and Inc 27/28 – depends on ULF-5 arrival of software load. Notable 27

28. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley HRP Assumptions & Risks ULF5 will launch within Inc 25/26. ULF6 and ULF7 will launch in Inc 27/28. NASA MARES Electronic Troubleshooting activity to be completed in Increment 25/26. WHC Anomaly concerning the blocked internal line which connects the UMS will be resolved with the flight (on ULF-6) of an adapter hose to bypass the A2 connection completely. 28

29. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Inc. 27/28 Open Work HRF Supply Kit Products –Use strikethrough function in IPV for Resupply activities where applicable UMS –ECR Products delivered Inc 25/26 – assume baselined by 27/28  No TIR Required (Inc 23/24 completed)  JIT Required  Chit may be required to secure use of SSC if Node3 SSC unavailable –OCR to identify changes from initial configuration 29

30. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Back Up Slides 30

31. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Spinal Elongation Operations –Spinal Elongation  Standing Height and Photo Downlink requirements identified in EPAS  Procedures in AOP to include Operator Procedure, Spinal Data Log (Seated Height), and Standing Height Cue Card; CR required to correct current version  Any delta from requirement to Final Flight Timeline will be documented in SOC OCR; HRF will attach updated products to reflect deltas  ULF6 Subjects: M. Kelly & Johnson, Coleman and Nespoli OPR  Spinal Elongation hardware will be stowed on ISS before and after Shuttle missions; hardware final return on ULF6 or ULF-7  Spinal Elongation implementation will vary by Shuttle  Spinal Elongation Procedures, Logs, & Cue Cards will be in Shuttle AOP (Assembly Operations Procedures) and return home Notable 31

32. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley FLEXIBLE ACTIVITIES UMS: 25S Crewmembers will be briefed for consent to participate in UMS Nom Check-out Operations. The E26 CDR has received validation testing training; however 25S FE6 is preferred for execution Actiwatch: Download/Initialization/battery changes can be done by any trained crew – Caveat: HRP will plan to utilize the Legacy Actiwatches throughout Inc 25/26 unless the Actiwatch has a non-recoverable malfunction SLAMMD: Set-up and Stow can be done by any trained crew HRF Facility Activities: Most HRP Facility are flexible as to when they need to be scheduled aside from the following: – HRF Supply Kit drawer inserts are launching on ULF5 with re-supplies launching on subsequent flights. Initial crew configuration activity will pull together all required contents and confirm initial configuration with photo documentation. Inventory activity will be performed near the end of Inc 25/26 to allow for planning of future resupply 32

33. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley HRF- RACK- PWRUP PRO-HRF-ACT CMD ESA-HRF-ACT HRF- RACK- PWRUP PRO-HRF-ACT CMD ESA-HRF-ACT Inc 23/24 Activation SupportCurrent Activation Support 60 Minutes 90 Minutes 33

34. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley New Sequence – Separate ESA Windows Current Activation SupportNew Activation Support 60 Minutes 30 Minutes ESA- HRF- WFSV* HRF- RACK- PWRUP PRO-HRF-ACT CMD ESA-HRF-ACT 60 Minutes 90 Minutes * ESA-HRF-WFSV window can be scheduled at any time before the PRO/ESA/HRF windows to allow for more flexibility when scheduling HRF Activations when KU&S coverage is not optimal. HRF- RACK- PWRUP PRO-HRF-ACT CMD ESA-HRF-ACT 34

35. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Section A Section A includes Steps 2-4 of HRF ISPR Rack Activation Procedure KU Requirement can be removed from Section A (COLOC can command the WFSV via S-Band and does not require KU-Band) ESA does initial WFSV settings to ~ 27kg/hr Section B Section B includes Steps 1 & 5-9 of HRF ISPR Rack Activation Procedure as well as HRF commanding to enable session specific payloads KU&S will be required for this section PRO sends command to enable polling ESA applies power to HRF Rack ESA enables Smoke detection monitoring HRF loads Configuration Files HRF sets Rack to Operational Mode HRF Configures Subsystem Valve ESA adjusts WFSV for activity (Flow Cases B-E) HRF Configures Payload Valves (if needed) HRF configures Rack for activity B A New Activation HRF- RACK- PWRUP PRO-HRF-ACT CMD 30 Minutes ESA- HRF- WFSV ESA-HRF-ACT 60 Minutes 35

36. Payload Operations Integration Working Group (POIWG) Jan 25-27 th, 2011 Human Research Program (HRP) Blue Bradley Acronyms, Abbreviations, Definitions CDRCommander CMDCommand C/OCheck out CSACanadian Space Agency DVDDigital Video Disc ESAEuropean Space Agency FTTFunctional Task Test GDSGas Delivery System HRFHuman Research Facility HRPHuman Research Program IPInternational Partner ISSInternational Space Station LMLockheed Martin NASANational Aeronautical Space Agency Portable PFSPortable Pulmonary Function System PFSPulmonary Function System PIGPressurized Inhalation Gases RCRefrigerated Centrifuge RICRack Interface Controller SLAMMDSpace Linear Acceleration Mass Measurement Device SSCShared Station Computer SWSoftware T61ptype of Portable Computer TBDTo Be Determined ULF6Utilization Logistics Flight4/STS-134 ULF7Utilization Logistics Flight5/STS-135 UMSUrine Monitor System URCUser Requirements Collection WHCWaste Hygiene Compartment 36