1. PRESENTATION BY: BRADLEY PELHAM CO-INVESTIGATOR SAMANTHA YEE COLLABORATOR DANNIE ZHABILOV PRINCIPAL INVESTIGATOR Envelope Glycoprotein 120 (gp120) in the Presence of Micro-Gravity

2. Background Envelope Glycoprotein Structure Purpose HIV-1 Infectious process

3. Objective To determine the effects of microgravity on the structure of glycoprotein 120 and whether or not the effects, if there are any, have an effect on the purpose of gp120.

4. Method Design (type 1 FME) Recombinant gp120 Protein folding assay

5. Theoretical Results The effects of a changed protein structure The effects on the binding of HIV-1 to T-cells

6. Conclusion Open new doors for HIV-1 treatment New explanation to protein folding

7. Acknowledgements Dr. Harry Zhabilov Nanoracks The Smithsonian Institution SSEP Mr. Wyeth Collo San Marino High School San Marino Unified School District San Marino PTSA Stephen and Mary Birch Foundation Center for the Advancement of Science in Space (CASIS), SSEP National Partner National Center for Earth and Space Science Education Subaru of America, Inc., SSEP National Partner