1. Automated Metered Dose Inhaler Presented By Group 11: Maria del Carmen Carrillo Jennifer B. Struble Loyrirk Temiyakarn

2. Background What is a Metered Dose Inhaler? What is a Metered Dose Inhaler? pocket-sized handheld inhaler delivers standardized dose of medication for bronchodilation Who Uses Them? Who Uses Them? Patients with asthma or chronic obstructive pulmonary disease (COPD)

3. Background Setting? Critical patients in hospitals Prescriptions for outpatient or in-home use How to Use? Shake Inhaler Hold up to mouth Press down on the inhaler to release the medicine as you start to breathe in slowly Hold breath for 10 seconds Repeat if necessary

4. Problem Definition Automatic Metered Dose Inhalant (MDI) delivery device: Automatic Metered Dose Inhalant (MDI) delivery device: Electromechanical, in-hospital inhalant drug delivery system Electromechanical, in-hospital inhalant drug delivery system Patients are mechanically ventilated and sedated Patients are mechanically ventilated and sedated Medication delivered automatically as prescribed electronically Medication delivered automatically as prescribed electronically Medication must be well shaken (homogenized with propellant) Medication must be well shaken (homogenized with propellant)

5. Design Factors Integration with existing endotracheal tubing Integration with existing endotracheal tubing Homogenization with propellant Homogenization with propellant Pressurization Pressurization Software Software User interface User interface Prescription error checking Prescription error checking

6. Project Status Preliminary Research Complete Standard MDI Present Research Endotracheal Tubing Proposed Research Ventilators Homogenizer

7. Working Design Integrated with existing tubing Integrated with existing tubing T connector T connector Prefabricated MDI canisters Prefabricated MDI canisters Aerochamber Aerochamber Vortexer to homogenize Vortexer to homogenize Laptop based prescription entry Laptop based prescription entry Similar to error reduction system, Guardrails® Safety Software, in Alaris “Smart” IV Pump Similar to error reduction system, Guardrails® Safety Software, in Alaris “Smart” IV Pump

8. Timeline Completed Work Completed Work Preliminary research Preliminary research Clearly defined design factors Clearly defined design factors Through Innovation Workbench Through Innovation Workbench Current Work Current Work Order components to start building prototype Order components to start building prototype Projected Timeline  Model A ~ End of January Mechanical components Testing ~ First week of February Implement corrections Model B ~ Second week of March Software included Testing ~ End of March Final prototype ~ April

9. References http://familydoctor.org/040.xml http://familydoctor.org/040.xml http://familydoctor.org/040.xml http://www.medlineplus.com/ http://www.medlineplus.com/ http://www.medlineplus.com/ http://www.alarismed.com/na/press/pres skit_bkgd.shtml http://www.alarismed.com/na/press/pres skit_bkgd.shtml http://www.alarismed.com/na/press/pres skit_bkgd.shtml http://www.alarismed.com/na/press/pres skit_bkgd.shtml http://www.drgreene.com/21_1377.html http://www.drgreene.com/21_1377.html http://www.drgreene.com/21_1377.html http://www.med.umich.edu/anes/tcpub/g lossary/anesthesia_glossary-05.htm http://www.med.umich.edu/anes/tcpub/g lossary/anesthesia_glossary-05.htm http://www.med.umich.edu/anes/tcpub/g lossary/anesthesia_glossary-05.htm http://www.med.umich.edu/anes/tcpub/g lossary/anesthesia_glossary-05.htm