1. Premedication Dr.M.Kannan MD DA Professor And HOD Department of Anaesthesiology Tirunelveli Medical College

2. Premedication Drugs administer 1-2 hours before induction of Anaesthesia

3. Why Premedication To Allay anxiety and fear Non Pharmacological -Assurance &Raport –Pharmacological -Benzodiazepanies -Diazepam -Medazolam -Lorozepam

4. Why Premedication To Reduce Secretion Salivary secretion Broncheal secretion Anticholinergic drug-Atropine -Glycopyrolate Tachycardia Hyperthermia

5. Why Premedication Enhances Hypnotic effect of General Anaesthetic Drugs -Less amount volatile Anaesthetics and nacotics

6. Why Premedication Reduces Postoperative Nausea and Vomiting Aspiration Psychological trauma

7. To Prevent Vomiting Metachlorpropamide Ondansetron Ranitidine

8. Why Premedication Produce Amnesia Benzodiazepine group -Diazepam 0.1-0.2mg/kg -Medazolam0.05mg/kg -Lorozepam

9. Why Premedication Gastric Content Volume ph -alkaline Metoclopramide- Sodium citrate

10. Why Premedication Attenuate sympathetoadrenal response -Laryngoscopy

11. Why Premedication Attenuate vagal reflex ? Bradycardia Traction of eye muscle in squint surgery -Repeated administration succinylcholine -Induction of Anaesthesia with halothane -Lighter plane of Anaethsia

12. Why Premedication Allay anxiety and fear Reduce Secretion Enhances Hypnotic effect of General Anaesthetic Drugs Reduces Postoperative Nausea and Vomiting Produce Amnesia Gastric Content Volume ph -alkaline Attenuate vagal reflex Attenuate sympathetoadrenal response

13. What Drugs ? Antisailagoge –Atropine/Glycopyrolate Sedative –Morphine -Pethedine -Benzodiazepaines -Barbiturates Antiemitics -Metachlorpropamide/Ondonsetron Disease Specific Drugs

14. Can we Give Fixed Pre.Med NO Cardiac –Avoid anticholinergics & Stiff sedatives Thyrotoxicosis- Avoid anticholinergic Head injury- Avoid sedatives Airway obstruction- Aviod sedatives Pregnancy- Avoid sedatives