1. CHM 410/1410

7. CHM 410/1410 Objectives: 1.Think like an analytical chemist 2.Avoid the ‘Black Box’ syndrome when using instrumentation 3.Learn and discuss current topics in environmental analytical chemistry

10. Lectures 2&3 How to get an accurate representation of environmental contamination Where to sample – air, water, soil, biota, humans

11. Lectures 5&6 Can’t analyze environmental samples directly, need to extract Considerations in extraction choice/development - How will the extracts be analyzed? - Concentration required? - Clean-up? - Sample contamination? Lecture 4 Assay techniques

12. Lecture 9 In-depth discussion of how chemicals move through a GC and into the detector Lecture 12 In-depth discussion of how chemicals move through an LC and into the detector Lecture 7&8 Chromatography, a relatively old technology, but very important

13. Lecture 10 GC detectors – FID and ECD Lecture 13 LC detectors – UV and fluorescence

14. Lecture 11 GC-MS hyphenation, how is this accomplished Lecture 16 LC-MS hyphenation, how is this accomplished

15. Lecture 17 Ionization/Fragmentation – EI, PCI, NCI

16. Lectures 18&19 Look at the guts of common mass spectrometers Lecture 20 Read current literature and discuss the analytical choices made

17. Lecture 21 How an FT-ICR works as well as applications Lecture 22 The use of mass spectrometry in atmospheric chemistry

18. Lectures 23&24 Metals, how are they analyzed? Differences and similarities to organic compounds

19. Lectures 25 Requests and review

20. CHM 410/1410 Format: PowerPoint slides will be posted on the website 1 week before class http://www.chem.utoronto.ca/coursenotes/CHM410/index.html Lectures will be recorded and posted on the website Primary literature ‘required’ reading will also be posted on the website 1 week prior to discussion