1. Cytopathology Challenge!
Weekly Cases
April 17, 2009

2. 1 FNA of abdominal mass: Colorectal adenocarcinoma
Prostatic adenocarcinoma
Lymphoma
Abscess
Sarcoma
lymphoglandular bodies 1

3. 2 Cervical LN FNA: papillary thyroid ca lymphoma multiple myeloma
reactive LN
HSV
Intranuclear pseudoinclusion. 2

4. 3 CSF from child: Unremarkable HSV CMV PNET Candida
Small round blue cells with molding. 3

5. 4 Liver FNA: Benign hepatocytes Benign ductal cells
Metastatic small cell carcinoma
Metastatic adenocarcinoma
Ecchinococcal cyst
Metastatic colorectal adenocarcinoma key features:
Columnar cells arranged in linear strips. Often with necrotic background.
Hepatocytes 4

6. 5 Pleural fluid: mesothelial cells empyema small cell carcinoma
squamous cell carcinoma
adenocarcinoma
“windows” 5

7. 6 Pancreas FNA: normal pancreas pseudocyst adenocarcinoma
endocrine neoplasm
lymphoma 6

8. 7 ThinPrep pap: Benign endometrial cells Follicular cervicitis HSIL
LSIL
Adenocarcinoma 7

9. ThinPrep pap:
NILM
Reactive cellular changes
HSIL
AGUS
LSIL 8

10. 9 ThinPrep pap: NILM Reactive cellular changes HSIL AGUS LSIL
Trichomonas
“Trich” halo; reactive phenomenon 9

11. 10 ThinPrep pap: NILM RCC HSIL AGUS LSIL
Cavitations in LSIL are larger than Trich halos and have a dark outer edge. 10