1. IOPtiMate™ OT-135P2 Technical Training – Part I System Description, Installation & Operation IOP-35-002(07)

2. Introduction to the system and it’s system parts Performing a system Set-up Getting familiar with the Control Unit Settings OBJECTIVES DISCLAIMER - Users are advised to read the User Manual before operating the system. In case of any mismatch between information mentioned herein to that presented in the User Manual, please refer to the last as the determines. AGENDA 1 IOP-35-002(07)

3. IOPtiMate TM System Components IOPtiMate™ Beam Manipulating Unit CO 2 Laser System Control Unit Ophthalmic Microscope Foot Switch 2 IOP-35-002(07)

4. 1 2 IOPtiMate TM Beam Manipulating Unit (BMU) The Beam Manipulating Unit (BMU) consists of 2 Sub-systems:  Micromanipulator (1)  Scanner (2) IOPtiMate TM Beam Manipulating Unit (BMU) 3 IOP-35-002(07)

5. 2 3 1 IOPtiMate TM Beam Manipulating Unit (BMU) Scanner component:  200 mm lens (1)  Focusing system (2)  Micrometer (3)  Articulated arm adaptor (4)  Scanner Cable Connector (5) The scanner enable the changes of the scanning parameters, such as shape and size, of the laser beam 5 4 IOPtiMate TM Beam Manipulating Unit (BMU) 4 IOP-35-002(07)

6. IOPtiMate TM Beam Manipulating Unit (BMU) The micromanipulator (MMP) directs the laser beam into the field of view MMP Components:  Folding mirror (1)  Positioning levers (2,3).  Fixation Screws (4)  Safety Screw (5) 14 4 2 3 5 IOPtiMate TM Beam Manipulating Unit (BMU) 5 IOP-35-002(07)

7. IOPtiMate TM Beam Manipulating Unit (BMU) Adaptor set for attaching the BMU onto the microscope Initial set-up in the OR – by qualified technician  Dovetail (1) permanently attached to OM (according to microscope type)  Adaptor Screw (2) fix the adaptor to the dovetail in semi-permanent manner  Adaptor (3) Holds the BMU  Dove tail insert part (4) align the adaptor and the OM 1 3 1 2 IOPtiMate TM Beam Manipulating Unit (BMU) 4 6 IOP-35-002(07)

8. IOPtiMate TM Cables The system cables:  Scanner Cable (1) connects the Control Unit to the BMU  Interface Cable (2) with two output connectors - connects the Control Unit to both the Foot Switch and the Laser system 1 2 IOPtiMate TM Cables 7 IOP-35-002(07)

9. IOPtiMate TM Cables The system cables:  Scanner Cable (1) connects the Control Unit to the BMU  Interface Cable (2) with one output connector - connects the Control Unit to the Laser system  Footswitch is connected directly to the laser. 1 2 IOPtiMate TM Cables 7 IOP-35-002(07)

10. System Cards The IOPtiMate TM system operates with 2 types of system cards : Patient Card Test Card System Cards 8 IOP-35-002(07)

11. User’s Manual Interface Cable BMU Module Control Unit Power Cable Quick Reference Guide Scanner Cable System Package – Outer Case 9 IOP-35-002(07)

12. Millimetric Ruler Adaptor BMU Allen Key Spare Parts Kit Dove Tail (Leica) Dove Tail (Zeiss) Adaptor Screw Ablation Cards Test Card System Package – BMU Module 10 IOP-35-002(07)

13. CO 2 Laser System Articulated Arm Foot Switch CO 2 Laser System Interface Cable Connector 11 IOP-35-002(07)

14. CO 2 Laser System Articulated Arm Foot Switch Interface Cable Connector

15. CO 2 Laser System Articulated Arm Foot Switch CO 2 Laser System Interface Cable Connector 11 Foot Switch connector IOP-35-002(07)

16. IOPtiMate TM System Set-Up 1. Set the BMU adaptor on the Microscope 2. Load the BMU onto the adaptor 3. Place the IOPtiMate TM Control Unit on the laser cradle 4. Connect the cables 5. Connect the laser articulated arm to the IOPtiMate TM BMU 6. Switch ON the IOPtiMate TM system and the laser system 7. Perform the daily tests (mandatory!) IOPtiMate TM System Set-Up 12 IOP-35-002(07)

17.  Verify that the dovetail is firmly connected to the microscope 2 Setting the BMU adaptor on the microscope 13 IOP-35-002(07)

18. Setting the BMU adaptor on the microscope  Slide the adaptor (1) onto the dovetail until the end of its movement range (2)  Tighten the fixation screw (3) by hand  Check that the adaptor hole and the OM are aligned by looking through the OM eyepiece. ** if needed change the dove tail insert part (see slide #6) location by using hex key 2mm– open screws (3). 2 2 1 Setting the BMU adaptor on the microscope 3 14 IOP-35-002(07)

19. 1.Verify that the BMU is undamaged - Inspect the focusing lens and gold folding mirror for substantial dirt or damage Optics as seen through the folding mirror 2.Mount the BMU onto the adaptor, manually lock with the 2 Fixation screws Loading the BMU on the adaptor 15 IOP-35-002(07)

20. Loading the BMU on the adaptor 3.Tight the Safety screw with hex key 2.5mm, then open ¼ turn 4.Open Fixation screws ~1 turn. Verify that BMU is secure and rotates freely 5.Tighten again the two Fixation screws to fix the BMU in the desired rotational position Loading the BMU on the adaptor 16 IOP-35-002(07)

21. Attaching the Control Unit to the Laser system Attach the Control Unit to the laser system via the cradle.  Slide the control unit into the cradle  Verify the Control Unit is positioned correctly and securely Attaching the Control Unit to the Laser system 17 IOP-35-002(07)

22. Attaching the Control Unit to the Laser system Attach the Control Unit to the laser system via the cradle.  Connect the plate to the laser cover  Connect the cradle to the plate  Slide the control unit into the cradle  Verify the Control Unit is positioned correctly and securely

23. Attaching the Control Unit to the Laser system Attach the Control Unit to the laser system via the cradle.  Connect the cradle to the laser handle  Slide the control unit into the cradle  Verify the Control Unit is positioned correctly and securely Attaching the Control Unit to the Laser system 17 1 2 3 45 6 Secure the holding using Allen key 2mm IOP-35-002(07)

24. Cable Connections Connect the Control Unit cables :  Verify that the main switch is in OFF position!  Verify that the electrical cable is DISCONNECTED from the mains!  Connect the Scanner cable side marked at end with Control Unit  Connect the Interface cable side marked at end with Control Unit  Tightly fasten the connector screws. Cable Connections 18 Scanner cable Interface cable Power cable IOP-35-002(07)

25. Cable Connections Scanner cable - Connect the BMU cables:  Connect the Scanner cable side marked at end with Scanner  Tightly fasten the connector screws. Cable Connections 19 IOP-35-002(07)

26. Cable Connections Interface cable with two output connectors - Connect the Control Unit to the Laser and to the Footswitch:  Connect the interface cable connector marked Laser to the rear laser panel (Footswitch inlet )  Connect interface cable connector marked Foot Switch to the footswitch cable Cable Connections 20 IOP-35-002(07)

27. Cable Connections Interface cable with one output connector - Connect the Control Unit to the Laser Connect the footswitch directly to the laser  Connect the interface cable to the Laser in the rear laser panel (remote interlock connector)  Connect Foot Switch directly to the laser (footswitch connector) Cable Connections 20 IOP-35-002(07)

28. Cable Connections Connect the Power cable:  Connect the power cable to rear panel  Assure secure connection to rear panel  Connect to a grounded AC wall outlet Cable Connections 21 IOP-35-002(07)

29. Laser Articulated Arm Connection Connect the Laser Articulated Arm:  Connect articulated arm to BMU articulated arm adaptor.  Turn and insert until the connection is secure Laser Articulated Arm Connection 22 IOP-35-002(07)

30. Sterile cover assembly Sterile cover adaptor assembly:  Slide the adaptor onto the BMU. 23 IOP-35-002(07)

31. Sterile cover assembly Sterile cover adaptor assembly:  Connect the adaptor to the BMU by screwing the two screws at the back of the BMU. 24 IOP-35-002(07)

32. Sterile cover assembly Sterile cover assembly:  At the beginning of the CLASS procedure, the sterile cover is placed according to document LGN-35-034, IOPtiMate™ Sterile BMU Cover Assembly Instruction.  Make sure you removed the lens protection plastic cover from the sterile cover rubber adaptor! 25 IOP-35-002(07)

33. Sterile cover assembly Sterile cover assembly:  It is very important to stretch the nylon bag of the sterile cover, such that no interference will be in the laser way. 26 IOP-35-002(07)

34. Control Unit Settings The Control Unit LCD displays the following:  Mode  Shape  Size  Status indications of the control unit  Indication (clock) that a procedure is running (not shown) Control Unit Settings 27 IOP-35-002(07)

35. Control Unit Settings The Mode parameter:  Preset Mode - Selection form 6 presets  Caliper Mode – 5 mm ruler  Manual Mode - Customizing size and shape Editing one of the preset parameters changes automatically to Manual mode and set the system in standby mode Navigation Between the modes using the +/- buttons Control Unit Settings 28 IOP-35-002(07)

36. Control Unit Settings The Shape parameter: The optional shapes:  Square  Rectangle  Arc Shape selection by navigation to the Shape line and using the arrow buttons Control Unit Settings 29 IOP-35-002(07)

37. Control Unit Settings The Size parameter: SIZE can be increased or reduced by navigation to the Size line using the arrow buttons and then using the +/- buttons Control Unit Settings 30 IOP-35-002(07)

38. Control Unit Status and Indication Notifications: STANDBY (default) – Whenever scan parameters are changed or STBY button is pressed READY (after confirmation by pressing ENTER) - The system is active Indicates that the IOPtiMate procedure is in progress Editing mode Control Unit 31 IOP-35-002(07)

39. Control Unit Cursor buttons: The left and right arrow buttons  enable movement from one line to another  enable movement within the lines Value buttons: The (+) and (-) buttons  enable and value changing The ENTER button must be pressed to confirm the settings Navigation Control Unit 32 IOP-35-002(07)

40. Control Unit Focus buttons: FOCUS button – Toggle ON and OFF the 2 focusing diodes on the treatment area.  A green light illuminates when the Focus is on. Control Unit 33 IOP-35-002(07)

41. Thank You! www.ioptima.co.il IOP-35-002(07)