1. Lecture 10 – Protein Function Based on Chapter 04 - Gene Function Copyright © 2010 Pearson Education Inc. Questions to answer in this chapter: What is the relationship between genes and enzymes? How do genes control biochemical pathways? What is the relationship between genes and nonenzymatic proteins? How can people be tested for a genetic disease mutation?

2. 1. Gene Control of Enzyme Structure

3. 3b. One-Gene–One-Enzyme Hypothesis

4. 4. Genetic Dissection of a Biochemical Pathway

5. 5. Genetically Based Enzyme Deficiencies in Humans

6. 6. Phenylketonuria 7. Albinism 8. Kartagener Syndrome

7. 9. Tay–Sachs Disease

8. 10. Gene Control of Protein Structure

9. 11a. Sickle-Cell Anemia

10. 11b. Sickle-Cell Anemia

11. 11c. Sickle-Cell Anemia

12. 12. Other Hemoglobin Mutants

13. Biochemical Genetics of Human Blood Type Peter J. Russell, iGenetics: Copyright © Pearson Education, Inc., publishing as Benjamin Cummings.

14. Biochemical Genetics of Human Blood Type Peter J. Russell, iGenetics: Copyright © Pearson Education, Inc., publishing as Benjamin Cummings. Antigenic reactions that characterize the human ABO blood types

15. 13a. Cystic Fibrosis

16. 13b. Cystic Fibrosis