1. THE BLOOD UNIT 10 (CHAPTER 17) VIDEO

2.  What substances does blood transport?  How does blood protect the body from infection?  How are blood cells manufactured? THINK ABOUT IT

3. 10 Lesson 1: The Function and Composition of the Blood Lesson 2: Blood Types Lesson 3: Blood Disorders and Diseases The Blood

4. LESSON 1 The Function and Composition of Blood video Chapter 10: The Blood

5.  Explain how blood transports nutrients and waste products, regulates body temperature, and fights infection.  Identify the solid and liquid components of blood.  Describe how the body manufactures blood cells.  Explain the physical properties and function of red blood cells, white blood cells, and platelets.  Describe the process of coagulation. OBJECTIVES

6. A LITTLE BIT OF BLOOD AND GORE (BLOOD MODELS)  Today we will be making blood our own blood just on a larger scale. Our blood is made up of four main components: white blood cells, red blood cells, platelets, and plasma - each of which serve specific purposes. At your tables make sure to pick up one of each of the following from the front. Come to the front to use other materials as needed.  Starting Materials i. Jar ii. Graduated cylinder iii. Plastic spoon

7.  the function of blood  the formed elements  physical properties of blood  plasma THE FUNCTION AND COMPOSITION OF BLOOD

8.  manufacturing blood cells  red blood cells  white blood cells  platelets THE FUNCTION AND COMPOSITION OF BLOOD

9. FUNCTIONS OF THE BLOOD  Transports  Gases  Waste products  Hormones  Enzymes  Nutrients  Blood cells  Plasma proteins (albumin, fibrinogen, and globulin)  Regulates  Temp  pH  Fluid and electrolytes  Protects  WBC  Antibodies  Clotting factors

10. FUNCTIONS OF THE BLOOD

11.  solid portion of blood  red blood cells  carry oxygen  white blood cells  immune response  platelets  clot THE FORMED ELEMENTS (45%)

12.  blood volume  4–7 liters of blood  taste  salty  color  bright red from artery  dull red from vein PHYSICAL PROPERTIES OF BLOOD

13.  liquid portion of blood  90% water  8% plasma proteins  2% mixture of  electrolytes  Nutrients  Ions  respiratory gases  hormones  waste products PLASMA (55%)

14. THE COMPOSITION OF BLOOD

15. Match these words with 1 – 4 below: plasma, platelets, bright red, red blood cell. 1. liquid portion of blood 2. carry oxygen 3. clot 4. arterial blood REVIEW AND ASSESSMENT

16. 10.1 CONTINUED  video video

17.  hematopoiesis  making new blood cells  stem cells make blood cells in  red bone marrow  lymphatic tissue MANUFACTURING BLOOD CELLS

18.  shape and size  disk-shaped  7 – 8 micrometers in diameter  hemoglobin  binds with oxygen RED BLOOD CELLS (ERYTHROCYTES)

19.  erythropoiesis  the process of making red blood cells  recycling  red blood cells live 120 days  phagocytosis–RBCs recycled  hemolysis–RBCs broken open RED BLOOD CELLS (ERYTHROCYTES)

20.  neutrophils  first responders WHITE BLOOD CELLS (LEUKOCYTES)  basophils  produce histamine  eosinophils  allergic reactions

21.  lymphocytes  T cells  B cells  form antibodies  monocytes  become macrophages WHITE BLOOD CELLS (LEUKOCYTES)

23.  granulocytes  neutrophils  perform phagocytosis  kill bacteria and fungi  eosinophils  destroy parasitic worms  control allergic responses  basophils  release histamine  active in allergic reactions CHARACTERISTICS OF WHITE BLOOD CELLS

24.  agranulocytes  lymphocytes  B cells produce antibodies  T cells and NK cells fight cancerous tumors and viruses  monocytes  perform phagocytosis  live longer than neutrophils  morph into macrophages and remove dead cell debris and attack microorganisms

25.  hemostasis  stops bleeding  steps of hemostasis  vessel wall injury and constriction  platelet aggregation  platelet plug formation and coagulation  blood clot formation and retraction PLATELETS (THROMBOCYTES)

26. THE PROCESS OF HEMOSTASIS

27. Fill in the blanks with: basophils, hemostasis, hemoglobin, or T cell. 1. _______________ is a type of lymphocyte. 2. _______________ produce histamine. 3. _______________ binds with oxygen. 4. _______________ stops bleeding. REVIEW AND ASSESSMENT

28. DRAWING ACTIVITY  As a group pick 4 classes of blood cells. Draw each blood cell write the description, function, life span, and deferential counts

29.  Why cant someone with type A blood receive blood from a person with type B blood?  What role does the Rh factor play in pregnant women? THINK ABOUT IT

30. LESSON 2 Blood Types video Chapter 10: The Blood

31.  Identify the four blood types.  Describe the role of antigens and antibodies in the blood.  Explain the Rh classification system and why it is important.  Identify the purpose of a complete blood count. OBJECTIVES

32.  blood types  the Rh classification system  complete blood count BLOOD TYPES

33.  A, B, AB, and O  antigens and antibodies  antigen  on surface of RBC, identify self and non-self  antibody  in blood plasma, mark foreign cells BLOOD TYPES

35.  agglutination  clumping of RBCs  universal recipient  blood type AB  universal donor  blood type O BLOOD TRANSFUSIONS

36.  Rh-positive individuals  have Rh factor antigen on RBCs  Rh-negative individuals  do not have Rh factor antigen on RBCs  Rh factor complications  erythroblastosis fetalis  RhoGAM THE RH CLASSIFICATION SYSTEM

37.  detects blood disorders or diseases COMPLETE BLOOD COUNT

38. True or False? 1. Blood type O is the universal donor. 2. Agglutination is the clumping of RBCs. 3. Antigens are in blood plasma. 4. Antibodies are on the surface of RBCs. 5. Rh factor is positive or negative. REVIEW AND ASSESSMENT

39. BLOOD TYPING RESOURCES  blood typing game blood typing game  Pg. 543 in textbook

40. LESSON 3 Blood Disorders and Diseases Chapter 10: The Blood

41.  Describe the differences between chronic and inherited anemias.  Identify common blood disorders and diseases.  Explain the difference between leukemia and multiple myeloma, two forms of blood cancer. OBJECTIVES

42.  What does it mean to be anemic?  Which blood disorder causes yellowing of the whites of the eyes and skin? THINK ABOUT IT

43.  anemia  jaundice  hemophilia  polycythemia  leukemia  multiple myeloma BLOOD DISORDERS AND DISEASES

44.  decrease in number of RBCs  insufficient amount of hemoglobin  acquired anemia  deficient diet, parasitic worms, disease  inherited anemia  genetic makeup ANEMIA

45.  iron-deficient anemia  insufficient dietary intake of iron  bleeding from intestinal worms  pregnancy ACQUIRED ANEMIAS

46.  aplastic anemia  damage to stem cells in bone marrow  causes  toxins  radiation therapy or chemotherapy  infectious disease  heredity ACQUIRED ANEMIAS

47.  pernicious anemia  intestines can not absorb vitamin B 12  anemias caused by chronic disease  rheumatoid arthritis  kidney disease  chronic infections  cancer ACQUIRED ANEMIAS

48.  sickle cell anemia  RBCs have abnormal shape  crises – painful episodes  Cooley’s anemia  cannot produce fully formed hemoglobin  cannot make enough RBCs INHERITED ANEMIAS

49.  yellow-colored skin and whites of the eyes  excess bilirubin  from breakdown of RBCs  possible liver damage  newborns JAUNDICE photobank.kiev.ua/Shutterstock.com

50.  hemophilia  inherited  blood does not clot  polycythemia  overproduction of RBCs  causes thick blood BLOOD DISORDERS

51.  cancer of the blood  acute lymphocytic leukemia  over production of lymphocytes  acute myeloid leukemia  too many myeloblasts LEUKEMIA

52.  chronic lymphocytic leukemia  high level of lymphocytes  chronic myeloid leukemia  too many granulocytes LEUKEMIA

53.  plasma cell cancer in bone marrow  may damage bone  treatable  incurable MULTIPLE MYELOMA

54. Match these words with 1 – 4 below: jaundice, leukemia, anemia, hemophilia. 1. cancer of the blood 2. blood does not clot 3. yellow colored skin 4. decrease in number of RBCs REVIEW AND ASSESSMENT