2. A potent metabolic agent, regulator of biochemical hair-loss processes
Stimucap
A potent metabolic agent, regulator of biochemical hair-loss processes

3. THE HAIR LOSS Not only “thanks” to the 5 -reductase enzyme
STIMUCAP
Not only “thanks” to the 5 -reductase enzyme
but also due to:
Fibrosis & inflammation of connective tissues
Involution
of hair follicle
Smaller and thiner hairs

4. HOW TO SOLVE THESE PROBLEMS?
Looking for a multiple functional compound that is able to :
Avoid these situations
Promote a more healthy status to the follicle
STIMUCAP

5. KALICHEM’S IDEA
STIMUCAP
Sodium DNA
CLA Glutathione
Stimucap

6. STIMUCAP
Cla - Glutahione

7. CLA – Conjugated linoleic acid Essential fatty acid
STIMUCAP
Precursor to anti-inflammatory substances
Regulator of nutrients’ transport (Component of the bio-membrane)
Able to become a dermal component, crossing the derma

8. GLUTATHIONE Essential fatty acid
STIMUCAP
Powerful antioxidant
Neutralizes free radicals that interfere with lipidic, proteic, enzimatic and DNA metabolism
Essential for the production of anti-inflammatory compounds by CLA
Essential in the elimination of toxic by-products of the metabolism

9. Sodium Dna
STIMUCAP

10. SODIUM DNA Essential for: metabolism Cell repairing
STIMUCAP
Essential for:
metabolism
Cell repairing
Tissue regeneration processes

11. Stimucap Sodium DNA STIMUCAP CLA Glutathione ANTINFLAMMATORY
+ ANTIOXIDANT
REGERATIVE POWER
Stimucap

12. A PICTURE…
STIMUCAP
Colourless
Slightly viscous
Hydro-soluble

13. In Vivo
Evaluation

14. Vs PRODUCTS STIMUCAP LOTION CONTROL LOTION
AQUA, ALCOHOL DENAT, POTASSIUM CLA GLUTATHIONE PEG-40 HYDROGENATED CASTOR OIL, PPG-26-BUTETH-26, PARFUM, SODIUM DNA
STIMUCAP
LOTION Vs
AQUA, ALCOHOL DENAT, MINOXIDIL, PEG-40 HYDROGENATED CASTOR OIL, PPG-26-BUTETH-26, PARFUM
CONTROL
LOTION

15. 30 volunteers (age between 29 and 55 years)
THE METHOD
STIMUCAP
30 volunteers (age between 29 and 55 years)
Volunteers affected by ALOPECIA & TELOGEN
EFFLUVIUM
15 volunteers treated with Stimucap
15 volunteers treated with Minoxidil
Once/day for 3 months
1,2 and 3 months)

16. Dermatological evaluation of the scalp Global tolerability
TESTS
STIMUCAP
Pull
Wash
Dermatological evaluation of the scalp
Global tolerability
Subjective evaluation

17. 1 - PULL TEST  HAIR RESISTANCE
STIMUCAP
Holding hair tuft exercising constant traction.
Count total number of hairs removed.
4 point scale:
SCORE
HAIR n° REMOVED IN 3 AREAS
> 6 1
6 - 4 2
3 – 1 3

18. 1 - PULL TEST  HAIR RESISTANCE
STIMUCAP
STIMUCAP
MINOXIDIL
HAIR RESISTANCE
MONTHS

19. under controlled standard
2 - WASH TEST  HAIR LOSS
STIMUCAP
Fallen hair counted
after washing
under controlled standard
conditions

20. 2 - WASH TEST  HAIR LOSS STIMUCAP MINOXIDIL # HAIR LOST MONTHS

21. 2 – DERMATOLOGICAL EVALUATION OF THE SCALP
STIMUCAP
Assessment of product’s global tolerability
Objective evaluation
4 point scale:
SCORE
EVALUATION
ABSENT 1
MODERATE 2
MILD 3
SEVERE

22. 3 – DERMATOLOGICAL EVALUATION OF THE SCALP
STIMUCAP
STIMUCAP
MINOXIDIL NO
adverse local reactions on the skin
BUT
Minoxidil has to be taken under medical control

23. Assessment of global tolerability
STIMUCAP
Assessment of global tolerability
Objective evaluation
5 point scale:
SCORE
EVALUATION
POOR 1
MODERATE 2
MEDIUM 3
GOOD 4
VERY GOOD

24. Minoxidil has to be taken under medical control
4 – GLOBAL TOLERABILITY
STIMUCAP
STIMUCAP
MINOXIDIL
GOOD
global tolerability
BUT
Minoxidil has to be taken under medical control

25. 5 – SUBJECTIVE EVALUATION  PLEASANTNESS
STIMUCAP
PERCEPTION of efficacy & pleasantness
6 point scale :
SCORE
EVALUATION
1,0
BAD
1,2 ..
1,4
1,6
1,8
2,0
VERY GOOD

26. 5 – SUBJECTIVE EVALUATION  PLEASANTNESS
STIMUCAP
STIMUCAP
MINOXIDIL
PLEASANTLESS
MONTHS

27. BETTER hair resistance LESS hair loss WELL TOLERATED product
CONCLUSION
STIMUCAP
BETTER hair resistance
LESS hair loss
WELL TOLERATED product
NO side effects
NO scalp irritation
EFFICIENT COADJUTANT
FOR TOPICAL TREATMENTS IN THE PREVENTION OF HAIR LOSS
STIMUCAP

28. STIMUCAP
Thank you
Via Pastore Botticino Sera (Brescia) Italy
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