1. ABO Presentation

2. Background of Ultraviolet (UV) and high energy visible (HEV)/blue light

3. Light is both beneficial and harmful to vision and health
Harmful Role
Cumulative damage to eye tissues
UV damage to cornea and lens
Implicated in cataracts and pterygium
Cumulative damage to the retina
Blue light, at certain wavelengths, causes damage to the retina
Implicated in age-related macular degeneration (AMD)
Essential Role
Visual functions
Visual acuity
Color perception
Contrast sensitivity
Non-visual functions
Sleep/wake cycle
Memory and mood
Hormonal balance

4. Dangers of uv light 100nm-380nm
UVC
UVB
UVA *
UV light damages the eyes just like it damage the skin
Daily UV exposure adds up over time and can cause irreversible damage to the eyes
UV is a major risk factor in many severe eye diseases, including cataract
Surgery is the only solution to cataract
20 million cataract procedures every year in the world
*ISO

5. Dangers and benefits of hev/blue light (380nm-500nm)
Dangers of Blue Light
High Energy light that can induce and accelerate retinal cell damage
Cumulative exposure to certain wavelengths of Blue Light can cause damage to the retina
Risk factor for the development of age-related macular degeneration (AMD)
Benefits of Blue Light
Blue Light, however is also beneficial for our vision and overall health
Visual acuity & color perception
Sleep/wake cycle, mood, and memory
Pupil size

6. Dangers of light to the eyeUV
BLUE LIGHT
Cataract
Normal
amd

7. AMD & Cataract cases expected to DOUBLE
Increasing incidence of cataract
and amd cases in the us
AMD & Cataract cases expected to DOUBLE
in the next 30 years
CATARACT POPULATION
AMD POPULATION
Source:

8. Sources of uv and hev/blue light

9. sunlight
On a cloudy day, up to 80% of the sun’s UV rays can pass through the clouds
Blue light proportion of daylight varies between 25% and 30%
Exposure to harmful light depends on the following factors:
Season
Time of day
Geographic location
Gaze direction

10. Artificial light Compact fluorescent lamps LEDs
Contain 25% harmful Blue Light
LEDs
Contain 35% harmful Blue Light
The cooler the white LED, the higher the blue proportion
By 2020, 90% of all light sources will be LED

11. blue-violet light RESEARCH

12. Research conducted by essilor & paris vision institute
Paris Vision Institute -  One of the most important research centers on eye diseases
In 2008, Essilor partnered with Paris Vision Institute for a eye health research program
First in-vitro tests in the ophthalmic industry with 10nm bands of HEV light exposure
Visible light spectrum split into 10 nanometer bands
Each band focused on retinal cells*
Specific bands induced maximum retinal cell death
*Based on in-vitro tests on swine retinal cells

13. Discovery of specific band of harmful blue-violet light
TOXIC nm
In partnership Paris Vision Institute, Essilor aims to offer the most complete eye protection against dangerous light including HEV.
First in-vitro tests in the ophthalmic industry with 10nm bands of HEV light exposure
Result: 40nm ( nm) of the HEV spectrum – known as Blue-Violet light – are most harmful.

14. Introduction to blue-violet light
AMD
Blue-Violet light ranges from 415 to 455 nanometers (nm) – the band of visible light most harmful to retinal cells
Cumulative exposure to Blue-Violet light can lead to retinal cell death
Blue-Violet light is one of the risk factors for the development of age-related macular degeneration (AMD)
AMD is the leading cause of severe vision loss and legal blindness in adults over 60
There is no cure for AMD today
Normal Vision
AMD Vision

15. blue-violet light emission from
led and other sources

16. Cognitive performance Pupillary constriction Color perception, acuity
Introduction to
blue-turquoise light
Sleep/wake cycle
Memory & mood
Cognitive performance
Pupillary constriction
Color perception, acuity
Blue-Turquoise light ranges from 465 to 495 nanometers (nm)
Blue-Turquoise light is essential for:
Pupillary Constriction Reflex
Retina’s natural protection against light overexposure
“Human biological clock” synchronization
Allows the right functioning of the sleep/ wake cycle, memory, mood, etc.
Visual acuity & color perception

17. Inadequate Blue-Turquoise light can desynchronize the sleep/wake cycle

18. Light scan™

19. NEED FOR A SELECTIVE LIGHT FILTER
Selective photo-filtration
HARMFUL nm
ESSENTIAL nm
Blue light is made up of both harmful and beneficial light
Harmful: Blue-Violet Light
Beneficial: Blue-Turquoise Light
UV Light, that is part of the invisible light spectrum, is very harmful to eyes
There is a need for a lens solution that protects eyes from the harmful light, but allows the beneficial visible light to pass through
NEED FOR A SELECTIVE LIGHT FILTER

20. Three key features of light scan™
Light Scan™ is a patented selective No-Glare technology
Key features of Light Scan:
Selectively filters out harmful Blue-Violet
Allows beneficial visible light, including Blue-Turquoise light, to pass through
Maintains excellent transparency of the lens

21. No-Glare Lenses
Protection Against Harmful Blue-Violet & UV Light

22. Front-side & back-side protection

23. Protection from uv
& blue-violet light

24. Crizal® prevencia™: front-side blue-violet light deflection
This graph shows the front-side reflection of Visible Light
20% Blue-Violet light deflected
Blue-Turquoise transmitted
Rest of visible light transmitted

25. Crizal® prevencia™: blue-violet light protection
Protection from Blue-Violet light
New No-Glare lens treatment
Features Light Scan™
Selectively deflects harmful Blue-Violet light by 20%
In recent lab tests, Crizal Prevencia lenses reduced retinal cell death by 25%*
First No-Glare lens on the market to selectively deflect harmful Blue-Violet and UV light
*Results from in-vitro tests on swine retinal cells

26. Crizal® prevencia™: back-side uv reflection protection

27. Crizal® prevencia™: uv light protection
25X MORE UV PROTECTION THAN GOING WITHOUT EYEWEAR*   
Protection from UV light: E-SPF® value of 25
Provides protection from UV light reflecting from back-side of the lens
Independent tests show up to 50% of UV exposure comes from the back and sides to hit the rear lens’ surface
Reflects four to eight times less UV light from the backside of the lens than most leading competitive No-Glare lenses on the market today
* E-SPF® is a global index rating the overall UV protection of a lens. E-SPF® was developed by Essilor International and endorsed by 3rd party experts. A lens rating of E-SPF® 25 means that an eye protected by the lens will receive 25 times less UV exposure than an unprotected eye. E-SPF® of 25 when a Crizal lens is made with lens material other than clear 1.5 plastic.

28. Crizal® prevencia™: at a glance
Light Scan™
Deflects 20% of harmful Blue-Violet light and in recent lab tests, reduced retinal cell death by 25%*+
Allows beneficial Blue-Turquoise light to pass through
Maintains excellent transparency for optimal vision
E-SPF® value of 25
Features the same level of protection against back-side UV reflection as all Crizal No-Glare lenses
25x more UV protection than going without eyewear
Features complete protection against the enemies of clear vision: glare, scratches, smudge, dust and water
*Results from in-vitro tests on swine retinal cells
+25% less light induced retinal cell death rate versus a standard clear lens. In in vitro experiments conducted by Essilor and Paris Vision Institute, Retinal Pigment Epithelium cells were exposed to Blue-Violet light, reproducing the physiological exposure to sunlight of the 40 year old eye.

29. Who needs most protection?
HIGH Exposure to White LED or Fluorescent Light Bulbs in offices/homes
Frequent user of LED computer monitor, Tablet and Smart Phone
At-risk for AMD (family history, smokers, etc.)

30. In conclusion
Educate at-risk AMD patients on the need to protect their eyes from harmful Blue-Violet light
Recommend Crizal® Prevencia™ lenses to your at-risk AMD patients to add another level of protection
Discuss the need to protect eyes from Blue-Violet light emitted from modern digital devices
Discuss their visual needs by asking open-ended questions, such as:
How do you protect your eyes on a daily basis?
Do you have a family history for macular degeneration/AMD?
How much time do you spend in front of digital devices?
How are you currently protecting your eyes against UV damage?

31. Thank you