1. BLOOD COMPATIBILITY

2. TESTING FOR COMPATIBILITY
DETERMINING BLOOD TYPES OF DONOR AND RECIPIENT.
CROSS-MATCHING: MIXING DONOR’S RBC’S WITH RECIPIENT’S PLASMA (ANTIBODIES).
recipient

3. “CROSS-REACTION” MIXING OF INCOMPATIBLE BLOOD TYPES.
AGGLUTINATION (CLUMPING) OR HEMOLYSIS OF RBC’S
POSSIBLE PATIENT DEATH FROM “TRANSFUSION REACTION”

4. WHAT BLOOD TYPES CAN BE MIXED?
*LAB 12-2: BLOOD COMPATIBILITY
DONOR RECIPIENT_____________
A B AB O A B AB O

5. SUMMARY A O AB B DONATE TO RECEIVE FROM TYPE O = UNIV. DONOR
TYPE AB = UNIV. RECIPIENT

6. GUIDELINES FOR DONATING BLOOD
MINIMUM 17 YEARS OLD
WEIGH > 110 LBS
HEMOGLOBIN > 12 g/100 mL
GENERAL GOOD HEALTH:
A. NEGATIVE FOR HIV OR AIDS
B. BLOOD PRESSURE < 180/100
C. NO HEART PROBLEMS > 6 MONTHS.
D. IMMUNIZATIONS > 28 DAYS
E. HEPATITIS OR JAUNDICE > AGE 11
F. FOREIGN TRAVEL (MALARIA COUNTRY) > 12 MO.
G. PREGNANCY: > 6 MONTHS AFTER DELIVERY
H. TRANSFUSION > 6 MONTHS
I. TATTOOS > 1 YEAR

7. Rh INCOMPATIBILITY
IN GENERAL: Rh (-) CAN GIVE TO Rh(+)  , BUT NOT Rh (+)  Rh (-) 
BABIES DEVELOP ERYTHROBLASTOSIS FETALIS : MOM = Rh (-) & BABY = Rh (+).

8. ERYTHROBLASTOSIS FETALIS
MOM’S Rh ANTIBODIES
EXPOSED TO BABY’S
Rh(+) ANTIGENS  DURING
PREGNANCY OR AT TIME
OF BIRTH.
2. MOM’S IMMUNE SYSTEM
PRODUCES ANTIBODIES
AGAINST Rh(+) ANTIGENS.

9. 3. ON 2ND + PREGNANCY, MOM’S ANTIBODIES
CROSS PLACENTA & ATTACK BABY’S CELLS
 ANEMIA
4. PREVENTION: INJECTING Rh(-) MOM
WITH ANTIBODIES (RhoGAM) DURING
PREGNANCY AND/OR WITHIN 72 HRS OF
DELIVERY
5. INACTIVATION OF BABY’S Rh (+) ANTIGENS

10. REVIEW