1. Date of download: 5/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Quality of Life After PCI vs CABG Among Patients With Diabetes and Multivessel Coronary Artery Disease: A Randomized Clinical Trial JAMA. 2013;310(15):1581-1590. doi:10.1001/jama.2013.279208 Patient Flow for the FREEDOM TrialPatients included in the primary analysis indicate the primary analytic population for the quality- of-life (QOL) study. a Patients who did not die, withdraw, or undergo coronary artery bypass graft (CABG) surgery or percutaneous coronary intervention (PCI) remained in the study but did not undergo revascularization. Figure Legend:

2. Date of download: 5/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Quality of Life After PCI vs CABG Among Patients With Diabetes and Multivessel Coronary Artery Disease: A Randomized Clinical Trial JAMA. 2013;310(15):1581-1590. doi:10.1001/jama.2013.279208 Seattle Angina Questionnaire ResultsMean scores are reported (error bars indicate 95% CIs) for the angina frequency, physical limitation, and quality-of-life subscales of the Seattle Angina Questionnaire (SAQ). Scores for each subscale range from 0 to 100 (reported by increments of 10) with higher scores representing better health status or quality of life. Figure Legend:

3. Date of download: 5/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Quality of Life After PCI vs CABG Among Patients With Diabetes and Multivessel Coronary Artery Disease: A Randomized Clinical Trial JAMA. 2013;310(15):1581-1590. doi:10.1001/jama.2013.279208 Frequency of Angina by Treatment GroupFrequency of angina by treatment group according to the Seattle Angina Questionnaire (SAQ)–angina frequency scale. Categories (with scores by increments of 10) were defined as no angina (score, 100), monthly angina (score, 70-90), weekly angina (score, 40-60), or daily angina (score, <40). See eTable 4 in the Supplement for exact data and numbers of patients. P value comparisons were determined using ordinal logistic regression. Figure Legend:

4. Date of download: 5/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Quality of Life After PCI vs CABG Among Patients With Diabetes and Multivessel Coronary Artery Disease: A Randomized Clinical Trial JAMA. 2013;310(15):1581-1590. doi:10.1001/jama.2013.279208 Frequency of Dyspnea-Related Limitation in Physical ActivityData are reported according to the Rose Dyspnea Scale (RDS; range, 0-4; higher scores represent more dyspnea). P value comparisons were determined using ordinal logistic regression. See eTable 6 in the Supplement for exact data. Figure Legend:

5. Date of download: 5/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Quality of Life After PCI vs CABG Among Patients With Diabetes and Multivessel Coronary Artery Disease: A Randomized Clinical Trial JAMA. 2013;310(15):1581-1590. doi:10.1001/jama.2013.279208 Subgroup Analysis of the Mean Treatment Effect of CABG vs PCI on the SAQ–Angina Frequency SubscaleAll subgroup counts are based on the baseline patient assessment. Treatment effects at 12 months, 24 months, associated 95% CIs, and interaction P values were derived from longitudinal random-effect growth-curve models. CABG, coronary artery bypass graft; LAD, left anterior descending artery; PCI, percutaneous coronary intervention; SAQ, Seattle Angina Questionnaire. Figure Legend: